Methylation status and DNase I sensitivity of immunoglobulin genes: changes associated with rearrangement.

DNA Methylation and Gene Function

1980 • 2,069 citations

Chromosomal Subunits in Active Genes Have an Altered Conformation

1976 • 1,842 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

Sequences at the somatic recombination sites of immunoglobulin light-chain genes

1979 • 859 citations

Chromatin structure of endogenous retroviral genes and activation by an inhibitor of DNA methylation

1981 • 475 citations

Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.

1979 • 472 citations

DNA methylation controls the inducibility of the mouse metallothionein-I gene in lymphoid cells

1981 • 464 citations

Simian virus 40 tandem repeated sequences as an element of the early promoter.

1981 • 462 citations

Interaction of HMG 14 and 17 with actively transcribed genes

1980 • 355 citations

The synthesis and processing of the messenger RNAs specifying heavy and light chain immunoglobulins in MPC-11 cells

1978 • 324 citations

Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression

1981 • 319 citations

Spacer DNA sequences upstream of the T-A-T-A-A-A-T-A sequence are essential for promotion of H2A histone gene transcription in vivo.

1980 • 287 citations

The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes.

1981 • 236 citations

Multiple Immunoglobulin Heavy-Chain Gene Transcripts in Abelson Murine Leukemia Virus-Transformed Lymphoid Cell Lines

1982 • 228 citations

Transcription of the unrearranged mouse Cκ locus: Sequence of the initiation region and comparison of activity with a rearranged Vκ-Cκ gene

1981 • 190 citations

Expression of a cloned adenovirus gene is inhibited by in vitro methylation.

1982 • 184 citations

Expression of the immunoglobulin C mu gene in mouse T and B lymphoid and myeloid cell lines.

1980 • 170 citations

Transcription of mouse kappa chain genes: implications for allelic exclusion.

1980 • 167 citations

A mutant immunoglobulin light chain is formed by aberrant DNA- and RNA-splicing events

1980 • 158 citations

Chromatin changes accompany immunoglobulin κ gene activation: a potential control region within the gene

1982 • 138 citations

Rearrangement of immunoglobulin heavy chain genes during B-lymphocyte development as revealed by studies of mouse plasmacytoma cells

1980 • 120 citations

Organization and expression of immunoglobulin genes in fetal liver hybridomas.

1981 • 116 citations

Functional significance and evolutionary development of the 5′-terminal regions of immunoglobulin variable-region genes

1982 • 105 citations

RNA splicing generates a variant light chain from an aberrantly rearranged κ gene

1980 • 95 citations

Rearranged and germline immunoglobulin .kappa. genes: different states of DNase I sensitivity of C.kappa. genes in immunocompetent and nonimmune cells

1981 • 88 citations

Methylation of simian virus 40 Hpa II site affects late, but not early, viral gene expression.

1982 • 85 citations

Transcriptional regulation of immunoglobulin V genes

1981 • 81 citations

DNase I-hypersensitive sites in the chromatin of immunoglobulin kappa light chain genes.

1983 • 70 citations

Expression of the J chain gene during B cell differentiation is inversely correlated with DNA methylation.

1981 • 58 citations

Immunoglobulin V/J recombination is accompanied by deletion of joining site and variable region segments.

1980 • 56 citations

Immunoglobulin heavy chain genes: demethylation accompanies class switching.

1981 • 52 citations

Differences in the nuclease sensitivity between the two alleles of the immunoglobulin kappa light chain genes in mouse liver and myeloma nuclei

1982 • 47 citations

Structure of the alpha-fetoprotein gene in the mouse.

1980 • 43 citations

Aberrant rearrangement of the κ light-chain locus involving the heavy-chain locus and chromosome 15 in a mouse plasmacytoma

1983 • 36 citations

Reorganization and Expression of Immunoglobulin Genes: Status of Allelic Elements

1981 • 22 citations