Peptoid-containing collagen mimetics with cell binding activity

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1984 • 3,580 citations

Peptoids: a modular approach to drug discovery.

1992 • 918 citations

Methods for the treatment of collagenous tissues for bioprostheses

1997 • 416 citations

Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen.

1991 • 401 citations

A cell surface receptor complex for collagen type I recognizes the Arg-Gly-Asp sequence.

1987 • 302 citations

Detachment of cells from culture substrate by soluble fibronectin peptides.

1985 • 301 citations

Identification in Collagen Type I of an Integrin α2β1-binding Site Containing an Essential GER Sequence

1998 • 270 citations

Cell attachment properties of collagen type VI and arg-gly-asp dependent binding to its α2(VI) and α3(VI) chains

1989 • 252 citations

Characterization of a type IV collagen major cell binding site with affinity to the alpha 1 beta 1 and the alpha 2 beta 1 integrins.

1991 • 230 citations

Analysis of alpha 1 beta 1, alpha 2 beta 1 and alpha 3 beta 1 integrins in cell--collagen interactions: identification of conformation dependent alpha 1 beta 1 binding sites in collagen type I.

1992 • 218 citations

Interaction of type IV collagen with the isolated integrins α1β1 and α2β1

1993 • 215 citations

Integrin and Arg-Gly-Asp Dependence of Cell Adhesion to the Native and Unfolded Triple Helix of Collagen Type VI

1993 • 212 citations

A comparison of the biological activities of the cell-adhesive proteins vitronectin and fibronectin

1989 • 205 citations

Polymer Networks with Grafted Cell Adhesion Peptides for Highly Biospecific Cell Adhesive Substrates

1994 • 189 citations

Collagen fabrics as biomaterials

1994 • 184 citations

Promotion of Fibroblast Adhesion by Triple-helical Peptide Models of Type I Collagen-derived Sequences

1996 • 176 citations

Integrin α2 I-domain is a binding site for collagens

1995 • 172 citations

Collagen-based Biomaterials

1996 • 170 citations

Enhanced cell attachment to anorganic bone mineral in the presence of a synthetic peptide related to collagen

1996 • 144 citations

Functional domains of cell adhesion molecules

1992 • 127 citations

Functional domains of cell adhesion molecules

1992 • 123 citations

Creating biomimetic micro-environments with synthetic polymer-peptide hybrid molecules

1998 • 123 citations

Identification of Integrin-like Matrix Receptors with Affinity for Interstitial Collagens

1989 • 123 citations

Integrins in the wounded and unwounded stratified squamous epithelium of the cornea.

1993 • 122 citations

Optimization of extruded collagen fibers for ACL reconstruction

1993 • 115 citations

Melanoma cell adhesion and spreading activities of a synthetic 124-residue triple-helical “mini-collagen”

1993 • 113 citations

Conformation dependence of integrin-type II collagen binding: Inability of collagen peptides to support α2β1 binding, and mediation of adhesion to denatured collagen by a novel α5β1-fibronectin bridge

1994 • 109 citations

Collagen mimetics

1998 • 108 citations

Surface topography can interfere with epithelial tissue migration

1998 • 106 citations

Promotion of cell adhesion by single-stranded and triple-helical peptide models of basement membrane collagen alpha 1(IV)531-543. Evidence for conformationally dependent and conformationally independent type IV collagen cell adhesion sites.

1994 • 83 citations

Enhancement of cell interactions with collagen/glycosaminoglycan matrices by RGD derivatization

1997 • 76 citations

Distribution of very late activation integrins in the human cornea. An immunohistochemical study using monoclonal antibodies.

1991 • 74 citations

Modification of glassy carbon surfaces with synthetic laminin-derived peptides for nerve cell attachment and neurite growth

1998 • 70 citations

Characterization of a hyaluronic acid-Arg-Gly-Asp peptide cell attachment matrix

1996 • 69 citations

Cell Adhesion Receptors for Native and Denatured Type I Collagens and Fibronectin in Rabbit Arterial Smooth Muscle Cells in Culture

1994 • 68 citations

Collagen-based structures containing the peptoid residue N-isobutylglycine (Nleu): Synthesis and biophysical studies of Gly-Pro-Nleu sequences by circular dichroism, ultraviolet absorbance, and optical rotation

1998 • 67 citations

Identification of Integrins Involved in Cell Adhesion to Native and Denatured Type I Collagens and the Phenotypic Transition of Rabbit Arterial Smooth Muscle Cells

1995 • 67 citations

Synthesis and cell attachment activity of bioactive oligopeptides: RGD, RGDS, RGDV, and RGDT

1991 • 60 citations

Integrins in Human Corneal Epithelium

1991 • 58 citations

Development of a biopolymeric keratoprosthetic material. Evaluation in vitro and in vivo.

1988 • 56 citations

Collagen-Like Triple Helices Incorporating Peptoid Residues

1996 • 55 citations

The A‐Domain of Integrin α2 Binds Specifically to a Range of Collagens but is not a General Receptor for the Collagenous Motif

1996 • 54 citations

Structural requirements for α1β1 and α2β1 integrin mediated cell adhesion to collagen V

1996 • 53 citations

Collagen-Based Structures Containing the Peptoid ResidueN-Isobutylglycine (Nleu): Synthesis and Biophysical Studies of Gly-Nleu-Pro Sequences by Circular Dichroism and Optical Rotation

1997 • 50 citations

Manipulation of cellular interactions with biomaterials toward a therapeutic outcome: A perspective

1994 • 48 citations

[8] Analysis of collagen receptors

1994 • 44 citations

A peptide from fibronectin cell-binding domain inhibits attachment of epithelial cells.

1988 • 43 citations

Collagen-Based Structures Containing the Peptoid Residue N-Isobutylglycine (Nleu). 6. Conformational Analysis of Gly-Pro-Nleu Sequences by ¹H NMR, CD, and Molecular Modeling

1996 • 40 citations

Evidence for the location of a binding sequence for the α2β1 integrin of endothelial cells, in the β1 subunit of laminin

1995 • 39 citations

Multiple Attachment Mechanisms of Corneal Epithelial Cells to a Polymer—Cells Can Attach in the Absence of Exogenous Adhesion Proteins through a Mechanism That Requires Microtubules

1997 • 39 citations

Quantitation of rabbit corneal epithelial cell outgrowth on polymeric substrates in vitro.

1990 • 37 citations

Collagen-Based Structures Containing the Peptoid Residue N-Isobutylglycine (Nleu): Conformational Analysis of Gly-Nleu-Pro Sequences by ¹H-NMR and Molecular Modeling

1997 • 36 citations

The Platelet Reactivity of Synthetic Peptides Based on the Collagen III Fragment α1(III)CB4

1997 • 35 citations

Involvement of integrins with adhesion-promoting, heparin-binding peptides of type IV collagen in cultured human corneal epithelial cells.

1995 • 33 citations

Mechanism of initial attachment of corneal epithelial cells to polymeric surfaces

1997 • 31 citations

Current Status of Synthetic Epikeratoplasty

1991 • 31 citations

Collagen organization in mandrel‐grown vascular grafts

1989 • 28 citations

Effects of biologically modified surfaces of synthetic lenticules on corneal epithelialization in vivo

1997 • 27 citations

Expression of integrin and organization of F-actin in epithelial cells depends on the underlying surface.

1994 • 25 citations

Identification of the epitope for a monoclonal antibody that blocks platelet aggregation induced by type III collagen

1997 • 20 citations

INTEGRINS AS RECEPTORS FOR EXTRACELLULAR MATRIX PROTEINS IN HUMAN CORNEA

1992 • 16 citations