Molecular cloning and sequence analysis of cDNAs for five major subunits of human proteasomes (multi-catalytic proteinase complexes)

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Identity of the 19S 'prosome' particle with the large multifunctional protease complex of mammalian cells (the proteasome)

1988 • 404 citations

The proteasome (multicatalytic protease) is a component of the 1500-kDa proteolytic complex which degrades ubiquitin-conjugated proteins.

1990 • 327 citations

A high molecular weight protease in the cytosol of rat liver. I. Purification, enzymological properties, and tissue distribution.

1986 • 327 citations

Sequence and structure of Clp P, the proteolytic component of the ATP-dependent Clp protease of Escherichia coli.

1990 • 264 citations

The multicatalytic proteinase of mammalian cells

1989 • 242 citations

Proteasomes (multi-protease complexes) as 20 S ring-shaped particles in a variety of eukaryotic cells.

1988 • 225 citations

Sequence of the lon gene in Escherichia coli. A heat-shock gene which encodes the ATP-dependent protease La.

1988 • 221 citations

A multiple-component, ATP-dependent protease from Escherichia coli.

1987 • 213 citations

Drosophila small cytoplasmic 19S ribonucleoprotein is homologous to the rat multicatalytic proteinase

1988 • 179 citations

The ATP-dependent Clp protease of Escherichia coli. Sequence of clpA and identification of a Clp-specific substrate.

1990 • 156 citations

Possible mechanism of nuclear translocation of proteasomes

1990 • 132 citations

Proteasomes are essential for yeast proliferation. cDNA cloning and gene disruption of two major subunits.

1990 • 127 citations

Prosomes

1986 • 122 citations

Eukaryotic pre-tRNA 5′ processing nuclease: Copurification with a complex cylindrical particle

1986 • 106 citations

The PROS-35 gene encodes the 35 kd protein subunit of Drosophila melanogaster proteasome.

1989 • 89 citations

Molecular cloning of cDNA for proteasomes (multicatalytic proteinase complexes) from rat liver: primary structure of the largest component (C2)

1989 • 86 citations

Molecular organization of a high molecular weight multi-protease complex from rat liver

1988 • 83 citations

Molecular cloning of cDNA for proteasomes from rat liver: primary structure of component C3 with a possible tyrosine phosphorylation site

1990 • 73 citations

cDNA cloning and sequencing of component C9 of proteasomes from rat hepatoma cells

1990 • 67 citations

A 20S particle ubiquitous from yeast to human

1987 • 67 citations

Proteinase yscE of yeast shows homology with the 20 S cylinder particles of Xenopus laevis

1988 • 66 citations

Prosomes, subcomplexes of untranslated mRNP

1990 • 65 citations

A high molecular weight protease in the cytosol of rat liver. II. Properties of the purified enzyme.

1986 • 56 citations

Involvement of proteasomes (multicatalytic proteinase) in ATP‐dependent proteolysis in rat reticulocyte extracts

1988 • 54 citations

The Drosophila PROS-28.1 gene is a member of the proteasome gene family

1990 • 54 citations

cDNA cloning and sequencing of component C8 of proteasomes from rat hepatoma cells

1990 • 50 citations

cDNA cloning and sequencing of component C5 of proteasomes from rat hepatoma cells

1990 • 48 citations

The latent form of macropain (high molecular weight multicatalytic protease) restores ATP-dependent proteolysis to soluble extracts of BHK fibroblasts pretreated with anti-macropain antibodies

1989 • 32 citations

The Drosophila PROS-29 gene is a new member of the PROS-gene family

1990 • 32 citations

The NH₂‐terminal residues of rat liver proteasome (multicatalytic proteinase complex) subunits, C2, C3 and C8, are Nα‐acetylated

1990 • 31 citations

RNA degrading activity is tightly associated with the multicatalytic proteinase, ingensin

1989 • 30 citations

Subunit interaction in tryptophan synthase of Escherichia coli: calorimetric studies on association of .alpha. and .beta.2 subunits

1979 • 29 citations