Down-regulation of proopiomelanocortin synthesis and beta-endorphin utilization in hypothalamus of morphine-tolerant rats

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

REGIONAL STUDIES OF CATECHOLAMINES IN THE RAT BRAIN‐I

1966 • 5,429 citations

Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal response by clonidine

1978 • 794 citations

The distribution of enkephalin-immunoreactive cell bodies in the rat central nervous system

1977 • 690 citations

Primary structure of the human Met- and Leu-enkephalin precursor and its mRNA

1982 • 672 citations

Neurons containing beta-endorphin in rat brain exist separately from those containing enkephalin: immunocytochemical studies.

1978 • 656 citations

Gene expression in rat brain

1983 • 344 citations

Opioid receptor types and membrane ion channels

1986 • 248 citations

Formulation of a Morphine Implantation Pellet Suitable for Tolerance-Physical Dependence Studies in Mice

1970 • 223 citations

Complete amino acid sequence of mouse pro-opiomelanocortin derived from the nucleotide sequence of pro-opiomelanocortin cDNA.

1983 • 207 citations

Mu and kappa opioids inhibit transmitter release by different mechanisms.

1985 • 161 citations

Morphine pellet implantation in rats: quantitative assessment of tolerance and dependence.

1973 • 146 citations

Stability of Met-enkephalin content in brain structures of morphine-dependent or foot shock-stressed rats

1977 • 139 citations

Pharmacokinetics and pharmacodynamics of subcutaneous morphine pellets in the rat.

1985 • 96 citations

Use of mRNA hybridization and radioimmunoassay to study mechanisms of drug-induced accumulation of enkephalins in rat brain structures.

1985 • 66 citations

Distribution of β-endorphin and related peptides in the hypothalamus and pituitary

1979 • 45 citations

Reserpine changes the dynamic state of enkephalin stores in rat striatum and adrenal medulla by different mechanisms

1985 • 42 citations

Phosphorylation of Rat and Human Adrenocorticotropin Related Peptides: Physiological Regulation and Studies of Secretion

1983 • 39 citations

Effect of chronic morphine treatment on β-endorphine biosynthesis by the rat neurointermediate lobe

1981 • 33 citations

In vivo studies of the regulation of neuropeptide stores in structures of the rat brain

1987 • 28 citations

Environmental modulation of analgesic tolerance induced by morphine pellets

1981 • 18 citations

A comparative study on the effects of morphine on central, peripheral and ganglionic stores of catecholamines.

1981 • 14 citations

Down regulation of hypothalamic proopiomelanocortin system during morphine tolerance.

1986 • 13 citations

Differential alterations by chronic treatment with morphine of pro-opiomelanocortin mRNA levels in anterior as compared to intermediate pituitary lobes of rats

1985 • 10 citations