Cancer: Functions of ras oncogenes

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation

1984 • 785 citations

Malignant transformation of early passage rodent cells by a single mutated human oncogene

1984 • 479 citations

Partial transformation of primary rat cells by the leftmost 4.5% fragment of adenovirus 5 DNA

1980 • 463 citations

Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene

1983 • 446 citations

Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein

1981 • 435 citations

Transformation of NIH 3T3 cells by microinjection of Ha-ras p21 protein

1984 • 379 citations

The roles of individual polyoma virus early proteins in oncogenic transformation

1982 • 366 citations

Expression of the large T protein of polyoma virus promotes the establishment in culture of "normal" rodent fibroblast cell lines.

1983 • 240 citations

Epidermal growth factor stimulates guanine nucleotide binding activity and phosphorylation of ras oncogene proteins

1984 • 203 citations

Resistance of human cells to tumorigenesis induced by cloned transforming genes.

1983 • 147 citations

Cellular responsiveness to growth factors correlates with a cell's ability to express the transformed phenotype

1983 • 100 citations

Differential genetic susceptibility of cultured human skin fibroblasts to transformation by Kirsten murine sarcoma virus

1977 • 61 citations