Diversity of lipid-based polyene formulations and their behavior in biological systems

Lipids, lipoproteins, triglyceride clearance, and cytokines in human immunodeficiency virus infection and the acquired immunodeficiency syndrome.

1992 • 784 citations

How do the polyene macrolide antibiotics affect the cellular membrane properties?

1986 • 746 citations

Drug Delivery Systems

1995 • 458 citations

Liposomal Amphotericin B for the Treatment of Systemic Fungal Infections in Patients with Cancer: A Preliminary Study

1985 • 412 citations

Phosphatodylethanolamine liposomes: drug delivery, gene transfer and immunodiagnostic applications

1992 • 365 citations

Biological approaches to the controlled delivery of drugs: a critical review.

1984 • 348 citations

Lipids, lipoproteins, triglyceride clearance, and cytokines in human immunodeficiency virus infection and the acquired immunodeficiency syndrome

1992 • 341 citations

Treatment and Prophylaxis of Disseminated Infection Due to Candida albicans in Mice with Liposome-Encapsulated Amphotericin B

1983 • 300 citations

Isolation and characterization of human plasma lipid transfer proteins.

1984 • 287 citations

Efficacy of amphotericin B encapsulated in liposomes (AmBisome) in the treatment of invasive fungal infections in immunocompromised patients

1991 • 281 citations

Low-density lipoprotein (LDL) receptor activity in human acute myelogenous leukemia cells

1978 • 279 citations

Liposomal and Lipid Formulations of Amphotericin B

1992 • 269 citations

Liposomes as in vivo carriers of adriamycin: reduced cardiac uptake and preserved antitumor activity in mice.

1982 • 260 citations

Low-density lipoprotein (LDL) receptor activity in human acute myelogenous leukemia cells

1978 • 259 citations

Purification and characterization of lipid transfer protein(s) from human lipoprotein-deficient plasma

1982 • 253 citations

laboratory investigation

2014 • 247 citations

Inter-relationship of lipids transferred by the lipid-transfer protein isolated from human lipoprotein-deficient plasma.

1983 • 243 citations

Liposomal amphotericin B (AmBisome): safety data from a phase II/III clinical trial

1991 • 236 citations

Lipoprotein (a) : structure, properties and possible involvement in thrombogenesis and atherogenesis

1990 • 230 citations

Liposome targeting in vivo: Problems and opportunities

1983 • 220 citations

Treatment of hepatosplenic candidiasis with liposomal-amphotericin B.

1987 • 217 citations

Liposomes in biological systems

1981 • 216 citations

Separation of a plasma phospholipid transfer protein from cholesterol ester/phospholipid exchange protein.

1983 • 195 citations

The hypertriglyceridemia of acquired immunodeficiency syndrome is associated with an increased prevalence of low density lipoprotein subclass pattern B.

1993 • 187 citations

Treatment of systemic fungal infections with liposomal amphotericin B.

1989 • 177 citations

Characterization, toxicity and therapeutic efficacy of adrïamycin encapsulated in liposomes

1982 • 176 citations

TARGETING OF DRUGS: IMPLICATIONS IN MEDICINE

1981 • 170 citations

Use of anionic liposomes for the reduction of chronic doxorubicin-induced cardiotoxicity.

1981 • 168 citations

Elevated low density lipoprotein receptor activity in leukemic cells with monocytic differentiation

1984 • 167 citations

Site–Specific (Targeted) Drug Delivery in Cancer Therapy

1983 • 166 citations

Amphotericin B lipid complex therapy of experimental fungal infections in mice

1991 • 160 citations

Liposomal protection of adriamycin-induced cardiotoxicity in mice.

1980 • 158 citations

Interaction between phospholipid bilayer membranes and the polyene antibiotic amphotericin B

1980 • 136 citations

Uptake of low density lipoproteins by human leukemic cells in vivo: relation to plasma lipoprotein levels and possible relevance for selective chemotherapy.

1990 • 126 citations

Interaction of Plasma Proteins and Lipoproteins with Amphotericin B

1984 • 125 citations

Reduced renal toxicity and improved clinical tolerance of amphotericin B mixed with Intralipid compared with conventional amphotericin B in neotropenic patients

1992 • 120 citations

Treatment of Systemic Fungal Infections With Liposomal Amphotericin B

1989 • 115 citations

An Emulsion Formulation of Amphotericin B Improves the Therapeutic Index When Treating Systemic Murine Candidiasis

1988 • 105 citations

A Textbook for the Clinical Application of Therapeutic Drug Monitoring.

1987 • 101 citations

Altered Tissue Distribution of Amphotericin B by Liposomal Encapsulation: Comparison of Normal Mice to Mice Infected with Candida albicans

1984 • 98 citations

Liposomal amphotericin B (AmBisome) in the treatment of fungal infections in neutropenic patients

1991 • 97 citations

Comparative Safety, Tolerance, and Pharmacokinetics of Amphotericin B Lipid Complex and Amphotericin B Desoxycholate in Healthy Male Volunteers

1991 • 94 citations

Treatment of Experimental Invasive Aspergillosis with Novel Amphotericin B/Cholesterol-Sulfate Complexes

1989 • 92 citations

Roles of liposome composition and temperature in distribution of amphotericin B in serum lipoproteins

1993 • 89 citations

Biochemistry of lipids, lipoproteins and membranes

1992 • 87 citations

Human apolipoprotein A-I forms thermally stable complexes with anionic but not with zwitterionic phospholipids.

1986 • 87 citations

Influence of lipoproteins on renal cytotoxicity and antifungal activity of amphotericin B

1994 • 86 citations

Isolation and specificity of a Mr 74,000 cholesteryl ester transfer protein from human plasma.

1987 • 85 citations

Decreased Toxicity of Liposomal Amphotericin B Due to Association of Amphotericin B with High‐Density Lipoproteins

1994 • 81 citations

Single-dose pharmacokinetics and tolerance of a cholesteryl sulfate complex of amphotericin B administered to healthy volunteers

1991 • 81 citations

Tissue Distribution of Amphotericin B Lipid Complex in Laboratory Animals

1991 • 77 citations

Pharmacokinetics, Tissue Distribution, and Toxicity of Free and Liposomal Amphotericin B in Diabetic Rats

1990 • 76 citations

Treatment of invasive aspergillus sinusitis with liposomal‐amphotericin B

1987 • 70 citations

Amphotericin B and its delivery by liposomal and lipid formulations

1993 • 70 citations

Liposomes as a drug delivery system

1981 • 63 citations

Interaction of lipid transfer protein with plasma lipoproteins and cell membranes

1990 • 61 citations

Concentration of neutral lipids in the phospholipid surface of substrate particles determines lipid transfer protein activity

1990 • 54 citations

Uptake of liposomes and liposome-encapsulated muramyl dipeptide by human peripheral blood monocytes.

1982 • 51 citations

Liposomes as Carriers of Antifungal Drugs

1988 • 49 citations

Partial purification and characterization of a triacylglycerol-transfer protein from rabbit serum

1980 • 49 citations

In vitro models for studying toxicity of antifungal agents

1992 • 48 citations

Structures of amphotericin B-cholesterol complex

1992 • 41 citations

Concentrations in serum and distribution in tissue of free and liposomal amphotericin B in rats during continuous intralipid infusion

1994 • 40 citations

Comparative efficacies of amphotericin B lipid complex and amphotericin B deoxycholate suspension against murine blastomycosis

1991 • 39 citations

Effect of lipid composition on the transfer of sterols mediated by non-specific lipid transfer protein (sterol carrier protein2)

1990 • 39 citations

Inhibition of the interaction between lipoproteins and amphotericin B by some delivery systems

1991 • 39 citations

Liposomes as Drug Delivery Systems

1998 • 38 citations

Transfer of the polyene antibiotic amphotericin B between single-walled vesicles of dipalmitoylphosphatidylcholine and egg-yolk phosphatidylcholine

1981 • 38 citations

Distribution of technetium-99m-labeled multilamellar liposomes in patients with Hodgkin's disease.

1985 • 38 citations

Phagocyte Transport as Mechanism for Enhanced Therapeutic Activity of Liposomal Amphotericin B

1994 • 35 citations

The Journal of Clinical Endocrinology

1941 • 34 citations

The role of liposomal amphotericin B in the treatment of systemic fungal infections.

1989 • 31 citations

Distribution and pharmacology of intravenous 99mTc-labeled multilamellar liposomes in rats and mice

1984 • 28 citations

Lipids, liposomes, and rational drug design.

1992 • 27 citations

Surface diffusion in human serum lipoproteins

1987 • 26 citations

The Interaction of Liposomal Amphotericin B and Serum Lipoproteins within the Biological Milieu

1994 • 24 citations

Quantification of Lipoprotein X and its Relationship to Plasma Lipid Profile during Different Types of Parenteral Nutrition

1984 • 22 citations

Biochimica et biophysica acta

1980 • 18 citations

Comparison of amphotericin B lipid complex with amphotericin B and SCH 39304 in the treatment of murine coccidioidal meningitis

1992 • 17 citations

Antibody-Mediated Targeting of Liposomes

1982 • 15 citations

Effects of Intralipid infusion on rat serum lipoproteins

1994 • 12 citations

Biochemistry and biology of plasma lipoproteins

1987 • 9 citations

Peroxidised linoleic acid and experimental pancreatitis

1986 • 8 citations

Serial Measurement of Plasma Cholesterol and Lecithin:Cholesterol Acyl Transferase Activity in Adults Receiving Total Parenteral Nutrition

1985 • 4 citations