The structural and biochemical basis of movement disorders in treatment with neuroleptic drugs and in extrapyramidal diseases

Verteilung Von Noradrenalin Und Dopamin (3-Hydroxytyramin) Im Gehirn Des Menschen Und Ihr Verhalten Bei Erkrankungen Des Extrapyramidalen Systems

1960 • 1,863 citations

Aromatic Amino Acids and Modification of Parkinsonism

1967 • 1,464 citations

Ascending Monoamine Neurons to the Telencephalon and Diencephalon

1966 • 1,205 citations

Demonstration and mapping out of nigro-neostriatal dopamine neurons

1964 • 796 citations

The occurrence, distribution and physiological role of catecholamines in the nervous system.

1959 • 665 citations

Functional Role of the Nigro‐Neostriatal Dopamine Neurons*)

1966 • 394 citations

Occurrence and distribution of dopamine in brain and other tissues

1959 • 367 citations

Cholinesterase-Containing Systems of the Brain of the Rat

1963 • 356 citations

INFLUENCE OF THE SUBSTANTIA NIGRA ON THE CATECHOLAMINE CONTENT OF THE STRIATUM

1965 • 340 citations

Role of Catecholamines in the Amphetamine Excitatory Response

1966 • 273 citations

Distribution of catechol compounds in human brain

1959 • 260 citations

Progress in Neuro-Genetics

1970 • 257 citations

NEUROLOGICAL SYMPTOMS IN PHARMAGOTHERAPY OF PSYCHOSES

1964 • 256 citations

Occurrence and Localization of Catechol Amines in the Human Brain

1961 • 241 citations

Verteilung des 5-Hydroxytryptamins (Serotonin) im Gehirn des Menschen und sein Verhalten bei Patienten mit Parkinson-Syndrom

1961 • 236 citations

Tardive Dyskinesia in Patients Treated with Major Neuroleptics: A Review of the Literature

1968 • 235 citations

Further evidence for the presence of nigro‐neostriatal dopamine neurons in the rat

1965 • 234 citations

Reversible and irreversible dyskinesia after treatment with perphenazine, chlorpromazine, reserpine and electroconvulsive therapy

1960 • 228 citations

Akinesia in Parkinson's disease

1959 • 211 citations

STRIATAL AMINES, EXPERIMENTAL TREMOR AND THE EFFECT OF HARMALINE IN THE MONKEY

1966 • 205 citations

Die Vorderseitenstrangdurchschneidung beim Menschen

1932 • 204 citations

MODIFICATION BY DRUGS OF THE METABOLISM OF 3,4‐DIHYDROXYPHENYLETHYLAMINE, NORADRENALINE AND 5‐HYDROXYTRYPTAMINE IN THE BRAIN

1965 • 200 citations

Adrenergic Mechanisms and Amphetamine Induced Abnormal Behaviour

1963 • 198 citations

Studies with reversible inhibitors of monoamine oxidase: Harmaline and related compounds

1958 • 177 citations

Effects of Hypothalamic Lesions on the Erythropoietic Response to Hypoxia in Rabbits¹

1964 • 174 citations

NEUROPATHOLOGICAL INVESTIGATION OF 28 BRAINS FROM PATIENTS WITH DYSKINESIA

1970 • 170 citations

Stereotype hyperactive behaviour produced by dopamine in the absence of noradrenaline

1967 • 167 citations

Neuropsychopharmacology.

1965 • 165 citations

On the distribution in brain of monoamines and of enzymes responsible for their formation

1959 • 159 citations

EFFERENT MUSCLE INNERVATION AND RIGIDITY.

1964 • 153 citations

OBSERVATIONS ON THE NATURE OF THE MUSCULAR RIGIDITY OF PARALYSIS AGITANS, AND ON ITS RELATIONSHIP TO TREMOR

1924 • 145 citations

Diethyldithiocarbamate and amphetamine stereotype behaviour

1966 • 133 citations

Über die Wirkungen des L-Dopa beim Menschen und deren Beeinflussung durch Reserpin, Chlorpromazin, Iproniazid und Vitamin B6

1960 • 130 citations

Herabgesetzte Konzentration der Homovanillinsäure im Gehirn von parkinsonkranken Menschen als Ausdruck der Störung des zentralen Dopaminstoffwechsels

1965 • 126 citations

MUSCLE TONE IN PARKINSONIAN STATES

1930 • 111 citations

PRODUCTION OF AN ALTERNATING TREMOR AT REST IN MONKEYS

1948 • 106 citations

The reflex activities of a decerebrate animal

1930 • 105 citations

Zur Biochemie des Parkinson-Syndroms des Menschen

1963 • 104 citations

Formation of Phenolic Acids in Brain after Administration of 3,4‐Dihydroxyphenylalanine

1962 • 103 citations

DOPA AND OTHER NATURALLY OCCURRING SUBSTANCES AS CAUSES OF STEREOTYPY AND RAGE IN RATS

1966 • 92 citations

Monoamines et système nerveux central

1962 • 87 citations

Chlorpromazin und Spastizit�t

1956 • 81 citations

On the Role of Monoamine Oxidase for the Inactivation of Dopamine in Brain

1960 • 81 citations

The effect of L-3, 4-dihydroxyphenylalanine and DL-5- -hydroxytryptophan on rigidity and tremor induced by reserpine, chlorpromazine and phenoxybenzamine

1964 • 80 citations

[Chlorpromazine and spasticity; an experimental electrophysiological study].

1956 • 76 citations

Effect of Brain Lesions on Striatal Monoamines in the Cat

1967 • 74 citations

“THE EXTRAPYRAMIDAL SYSTEM AND NEUROLEPTICS”

1960 • 70 citations

The red nucleus and its efferent nervous pathways in the monkey

1966 • 69 citations

EFFECT OF DEAFFERENTATION ON HUMAN PHYSIOLOGICAL TREMOR

1967 • 60 citations

Reciprocal Effects on α‐ and γ‐Motoneurones of Drugs Influencing Monoaminergic and Gholinergic Transmission

1966 • 59 citations

Neurochemical bases of tremor and other disorders of movement.

1966 • 58 citations

THE PERSISTANCE OF AMPHETAMINE STEREOTYPIES OF RATS IN SPITE OF STRONG SEDATION

1966 • 53 citations

Microelectrode studies of unit discharges in the sensorimotor cortex

1960 • 48 citations

Influence of the Substantia Nigra on the Concentration of 5-Hydroxytryptamine and Dopamine of the Striatum

1965 • 48 citations

The role of amines in the etiology of schizophrenia

1968 • 44 citations

EFFECTS OF L‐DOPA ON PHARMACOLOGICAL PARKINSONISM

1966 • 42 citations

Psychopharmacology frontiers

1960 • 42 citations

Extrapyramidal side effects and clinical response to the phenothiazines.

1961 • 42 citations

The mechanism of bradykinesia in parkinsonism

1966 • 40 citations

A DISCUSSION OF THE MODES OF ACTION OF DRUGS WHICH INCREASE THE CONCENTRATION OF 4‐HYDROXY‐3‐METHOXYPHENYLACETIC ACID (HOMOVANILLIC ACID) IN THE STRIATUM OF THE MOUSE

1967 • 39 citations

Therapeutic Value of Thioproperazine and the Importance of the Associated Neurological Disturbances

1961 • 39 citations

Striatal and spinal lesions eliminating reserpine and physostigmine rigidity

1967 • 36 citations

Physiological Mechanisms of Tremor and Rigidity in Parkinsonism

1965 • 29 citations

Das Verhalten des Dopamin-Metaboliten Homovanillinsäure im Gehirn von normalen und Parkinson-kranken Menschen

1964 • 26 citations

Verhalten des Dopamins (=3-Hydroxytyramin) im Nucleus caudatus nach elektrischer Koagulation des Globus pallidus

1964 • 25 citations

Neurophysiological Ideas on Pallidotomy and Ventrolateral Thalamotomy for Hyperkinesis

1962 • 20 citations

[Experimental neurological syndromes & psychiatric therapy. I. Neurological effects of a new important neuroleptic drug, RP 7843].

1959 • 16 citations

The Influence of the Nigro‐Neostriatal Dopamine Pathway on Spinal Motoneuron Activity

1971 • 16 citations

[Reactions of intolerance to chlorpromazine].

1956 • 14 citations

The Scientific Basis of Drug Therapy in Psychiatry

1965 • 13 citations

Parkinsonism and its treatment.

1961 • 12 citations

Thérapeutique par médication neuroleptique obtenue en réalisant systématiquement des états parkinsoniformes.

1956 • 12 citations

Effects of lesions in the substantia nigra upon subthalamic dyskinesia in the monkey

1965 • 11 citations

Psychopathologie und Klinik des Parkinsonismus vor und nach stereotaktischen Operationen

1967 • 10 citations

THE PATHOPHYSIOLOGY OF PARKINSONIAN TREMOR, RIGIDITY, AND HYPOKINESIA

2009 • 9 citations

Microelectrode studies in monkeys with a postural tremor.

1961 • 7 citations

Neurophysiology of tremor.

1966 • 5 citations

Effect of phenothiazines on dopamine metabolism and biochemistry of Parkinson's disease.

1968 • 5 citations

THE BASAL GANGLIA IN PARKINSONISM1

1960 • 5 citations

Physiological mechanisms in parkinsonism.

1961 • 4 citations

PHYSIOLOGICAL TREMOR

1967 • 4 citations