A mutant beta-tubulin confers resistance to the action of benzimidazole-carbamate microtubule inhibitors both in vivo and in vitro

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

A theory of linear and helical aggregations of macromolecules

1962 • 746 citations

The effects of methyl (5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl) carbamate, (R 17934; NSC 238159), a new synthetic antitumoral drug interfering with microtubules, on mammalian cells cultured in vitro.

1976 • 422 citations

Interaction of oncodazole (R 17934), a new anti-tumoral drug, with rat brain tubulin

1976 • 366 citations

Mode of action of antifungal agents

1984 • 221 citations

Identification of the pleiotropic cell division cycle gene NDA2 as one of two different α-tubulin genes in schizosaccharomyces pombe

1984 • 216 citations

Purification of yeast tubulin by self-assembly in vitro

1981 • 203 citations

Interaction of anthelmintic benzimidazoles and benzimidazole derivatives with bovine brain tubulin

1978 • 201 citations

Use of monoclonal antibodies to analyse the expression of a multi‐tubulin family

1985 • 167 citations

Cytoskeletal components of the vertebrate neuromuscular junction: vinculin, alpha-actinin, and filamin.

1983 • 153 citations

Two cell division cycle genes NDA2 and NDA3 of the fission yeast Schizosaccharomyces pombe control microtubular organization and sensitivity to anti-mitotic benzimidazole compounds

1983 • 150 citations

Identification of a gene for α-tubulin in Aspergillus nidulans

1979 • 136 citations

Cell type-dependent expression of tubulins in Physarum.

1983 • 107 citations

Mutants of chinese hamster ovary (cho) cells with altered colcemid-binding affinity

1979 • 85 citations

Microtubule Stability and Assembly in Living Cells: The Influence of Metabolic Inhibitors, Taxol and pH

1982 • 81 citations

A Mechanism of Cellular Resistance to Drugs that Interfere with Microtubule Assemblya

1986 • 73 citations

Involvement of a particular species of beta-tubulin (beta 3) in conidial development in Aspergillus nidulans.

1985 • 66 citations

GENETIC ANALYSIS OF RESISTANCE TO BENZIMIDAZOLES IN PHYSARUM: DIFFERENTIAL EXPRESSION OF β-TUBULIN GENES

1984 • 63 citations

In vitro assembly of microtubule proteins from myxamoebae of Physarum polycephalum

1980 • 60 citations

Structural and functional alterations in microtubule protein from Chinese hamster ovary cell mutants.

1981 • 60 citations

GENETICS OF THE TUBULIN GENE FAMILIES OF PHYSARUM

1984 • 47 citations

A Correlation between in Vivo and in Vitro Effects of the Microtubule Inhibitors Colchicine, Parbendazole and Nocodazole on Myxamoebae of Physarum polycephalum

1981 • 45 citations

Genetic Factors Determining the Growth of Physarum polycephalum Amoebae in Axenic Medium

1978 • 41 citations

Binding of parbendazole to tubulin and its influence on microtubules in tissue-culture cells as revealed by immunofluorescence microscopy

1981 • 41 citations

Identification of tubulin isoforms in the plasmodium of Physarum polycephalum by in vitro microtubule assembly.

1984 • 28 citations

A Comparison of the Proteins of the Amoebal and Plasanodial Phases of the Slime Mould, Physarum polycephalum

2005 • 23 citations

Mutants of Chinese hamster ovary cells with altered sensitivity to taxol and benzimidazole carbamates

1982 • 19 citations