The use of genetically altered astrocytes to provide nerve growth factor to adrenal chromaffin cells grafted into the striatum

Estimation of nuclear population from microtome sections

1946 • 4,378 citations

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue.

1980 • 3,822 citations

Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system

1970 • 1,980 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation.

1985 • 941 citations

RNA tumor viruses

1982 • 833 citations

Contemporary research methods in neuroanatomy

1971 • 738 citations

Open Microsurgical Autograft of Adrenal Medulla to the Right Caudate Nucleus in Two Patients with Intractable Parkinson's Disease

1987 • 676 citations

Transplantation of adrenal medullary tissue to striatum in parkinsonism

1985 • 601 citations

Control of Enzymatic Synthesis of Adrenaline in the Adrenal Medulla by Adrenal Cortical Steroids

1966 • 558 citations

Enkephalin-like immunoreactivity in gland cells and nerve terminals of the adrenal medulla

1978 • 554 citations

Development and regional expression of beta nerve growth factor messenger RNA and protein in the rat central nervous system.

1986 • 525 citations

Grafting Genetically Modified Cells to the Damaged Brain: Restorative Effects of NGF Expression

1988 • 508 citations

Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor

1983 • 474 citations

Nerve growth factor-induced fiber outgrowth from isolated rat adrenal chromaffin cells: impairment by glucocorticoids.

1978 • 468 citations

Environmental influences in the development of neural crest derivatives: glucocorticoids, growth factors, and chromaffin cell plasticity

1985 • 406 citations

Adrenal Medulla Grafts Enhance Recovery of Striatal Dopaminergic Fibers

1987 • 398 citations

Injury-induced neuronotrophic activity in adult rat brain: correlation with survival of delayed implants in the wound cavity

1983 • 389 citations

Multicenter Study of Autologous Adrenal Medullary Transplantation to the Corpus Striatum in Patients with Advanced Parkinson's Disease

1989 • 291 citations

Transplantation in Parkinson's disease: Two cases of adrenal medullary grafts to the putamen

1987 • 273 citations

Chronic implants of chromaffin tissue into the dopamine-denervated striatum. Effects of NGF on graft survival, fiber growth and rotational behavior

1985 • 259 citations

Evidence of Adrenaline and Noradrennline in Separate Adrenal Medullary Cells¹

1954 • 243 citations

NGF receptor reexpression and NGF-mediated cholinergic neuronal hypertrophy in the damaged adult neostriatum

1989 • 241 citations

A 6-hydroxydopamine-induced selective parkinsonian rat model

1989 • 241 citations

Nerve growth factor-induced transformation of immature chromaffin cells in vivo into sympathetic neurons: effect of antiserum to nerve growth factor.

1979 • 225 citations

NGF gene expression in actively growing brain glia

1991 • 210 citations

Adrenal medullary autografts into the basal ganglia of Cebus monkeys: Injury-induced regeneration

1988 • 205 citations

Intracerebral adrenal medulla grafts: A review

1990 • 179 citations

Histochemistry and Cell Biology of Autonomic Neurons, SIF Cells, and Paraneurons

1981 • 155 citations

Autopsy findings in a patient who had an adrenal‐to‐brain transplant for Parkinson's disease

1989 • 155 citations

The output of neuronotrophic and neurite-promoting agents from rat brain astroglial cells: a microculture method for screening potential regulatory molecules

1985 • 148 citations

NGF-like trophic support from peripheral nerve for grafted rhesus adrenal chromaffin cells

1990 • 147 citations

Postmortem analysis of adrenal–medulla–to–caudate autograft in a patient with parkinson's disease

1989 • 139 citations

Adrenocortical control of the biosynthesis of epinephrine and proteins in the adrenal medulla.

1972 • 137 citations

Differential RNA splicing predicts two distinct nerve growth factor precursors

1986 • 136 citations

Type II glucocorticoid receptors are expressed in oligodendrocytes and astrocytes

1990 • 134 citations

Clinical, biochemical, and neuropathologic findings following transplantation of adrenal medulla to the caudate nucleus for treatment of Parkinson's disease

1989 • 123 citations

The distribution of vasoactive intestinal peptide in the rat adrenal cortex and medulla

1984 • 120 citations

Synthesis/secretion of nerve growth factor is associated with cell growth in cultured mouse astroglial cells

1987 • 117 citations

Nerve growth factor-induced neurite outgrowth from normal human chromaffin cells.

1980 • 111 citations

Secretion of nerve growth factor in cultures of glial cells and neurons derived from different regions of the mouse brain

1989 • 93 citations

Distribution of Adrenaline and Noradrenaline in the Adrenal Medulla

1955 • 93 citations

Catecholamine content of intracerebral adrenal medulla grafts

1983 • 91 citations

Visualization of migration of transplanted astrocytes using polystyrene microspheres

1988 • 88 citations

Comparison of adrenal medullary, carotid body and PC12 cell grafts in 6-OHDA lesioned rats

1988 • 82 citations

Adrenal medullary transplant to the striatum of patients with advanced Parkinson's disease

1990 • 82 citations

High-performance liquid chromatography with electrochemical detection as a highly efficient tool for studying catecholaminergic systems. I. Quantification of noradrenaline, adrenaline and dopamine in cultured adrenal medullary cells

1981 • 80 citations

Long-term effects of dexamethasone and nerve growth factor on adrenal medullary cells cultured from young adult rats

1982 • 79 citations

Neuropeptide tyrosine in the rat adrenal gland—immunohistochemical and in situ hybridization studies

1988 • 77 citations

Neuropeptide Y in the adrenal gland: Characterisation, distribution and drug effects

1986 • 72 citations

Intraventricular NGF infusion in the mature rat brain enhances sympathetic innervation of cerebrovascular targets but fails to elicit sympathetic ingrowth

1989 • 67 citations

Adrenal Medullary Autograft Transplantation Into the Striatum of Patients With Parkinson's Disease

1989 • 64 citations

C6 glioma cell-conditioned medium induces neurite outgrowth and survival of rat chromaffin cells in vitro: comparison with the effects of nerve growth factor.

1984 • 60 citations

Asynchronous appearance and topographic segregation of neuropeptide- containing cells in the developing rat adrenal medulla

1990 • 58 citations

Appearance of enkephalin-immunoreactivity in rat adrenal medulla following treatment with nicotinic antagonists or reserpine

1983 • 56 citations

Purification of bovine adrenal chromaffin cells by differential plating

1981 • 56 citations

Developmental changes in the responses of rat chromaffin cells to neuronotrophic and neurite-promoting factors

1985 • 55 citations

Regulation of phenylethanolamine N‐methyltransferase (PNMT) mRNA in the rat adrenal medulla by corticosterone

1989 • 54 citations

Chromaffine cells can innervate brain tissue: Evidence from intraocular double grafts

1980 • 53 citations

Effects of cell culture conditions, nerve growth factor, dexamethasone, and cyclic AMP on adrenal chromaffin cells in vitro.

1980 • 43 citations

Cografts of adrenal medulla with C6 glioma cells in rats with 6-hydroxydopamine-induced lesions

1990 • 42 citations

Glucocorticoid effects on phenylethanolamine N-methyltransferase (PNMT) in explants of embryonic rat medulla oblongata

1987 • 41 citations

Lineage Analysis and Immortalization of Neural Ceils via Retrovirus Vectors

2003 • 38 citations

Chapter 6 Neurono-glial interactions and neural plasticity

1990 • 32 citations

Retrovirus-mediated gene transfer of beta-nerve growth factor into mouse pituitary line AtT-20.

1988 • 31 citations

Utilization of unilateral and bilateral stereotactically placed adrenomedullary-striatal autografts in parkinsonian humans

1990 • 31 citations

Organization, fine structure, and viability of the human adrenal medulla: Considerations for neural transplantation

1988 • 31 citations

Nerve growth factor and dexamethasone specify the catecholaminergic phenotype of cultured rat chromaffin cells: Dependence on developmental stage

1985 • 29 citations

Autocrine Differentiation of PC12 Cells Mediated by Retroviral Vectors

1990 • 29 citations

Role of glucocorticoids in expression and development of phenylethanolamine N-methyltransferase (PNMT) in cells derived from the neural crest: A review

1983 • 28 citations

ADRENALINE AND NORADRENALINE IN THE ADRENAL MEDULLA DURING POSTNATAL DEVELOPMENT OF THE RAT12

1957 • 25 citations

Effect of hypophysectomy on adrenal dopamine -hydroxylase activity in the rat.

1971 • 25 citations

Differential Effects of Nerve Growth Factor and Ciliary Neuronotrophic Factor on Catecholamine Storage and Catecholamine Synthesizing Enzymes of Cultured Rat Chromaffin Cells

1987 • 23 citations

Survival and differentiation within the adult mouse striatum of grafted rat pheochromocytoma cells (PC12) genetically modified to express recombinant β-NGF

1991 • 22 citations

Utilization of Unilateral and Bilateral Stereotactically Placed Adrenomedullary-Striatal Autografts in Parkinsonian Humans: Rationale, Techniques, and Observations

1990 • 22 citations

Production of “ectopic” vasoactive intestinal peptide-like immunoreactivity in normal human chromaffin cell cultures

1985 • 17 citations

Neuronal properties of monkey adrenal medulla in vitro

1986 • 17 citations

Aged adrenal medullary tissue survives intraocular grafting, forms nerve fibers and responds to nerve growth factor

1989 • 12 citations

Molecular and cellular mechanisms of neuronal plasticity in normal aging and Alzheimer's disease

1990 • 10 citations