Early Events of the Immune Response Mediated by Leukocyte Integrins

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Purified intercellular adhesion molecule-1 (ICAM-1) is a ligand for lymphocyte function-associated antigen 1 (LFA-1)

1987 • 1,712 citations

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN-gamma production.

1988 • 917 citations

Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1

1989 • 837 citations

The Leukocyte Integrins

1989 • 542 citations

Regulation of the fibronectin receptor affinity by divalent cations.

1988 • 441 citations

Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones

1986 • 437 citations

The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen.

1989 • 422 citations

Cotransfection of ICAM-1 and HLA-DR reconstitutes human antigen-presenting cell function in mouse L cells

1989 • 389 citations

The function of human intercellular adhesion molecule‐1 (ICAM‐1) in the generation of an immune response

1988 • 351 citations

The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.

1989 • 343 citations

Functional evidence that intercellular adhesion molecule‐1 (icam‐1) is a ligand for lfa‐1d‐ependent adhesion in t cell‐mediated cytotoxicity

1988 • 322 citations

Regulated expression of Mg2+ binding epitope on leukocyte integrin alpha subunits.

1989 • 321 citations

Monoclonal antibody to a novel lymphocyte function-associated antigen (LFA-1): mechanism of blockade of T lymphocyte-mediated killing and effects on other T and B lymphocyte functions.

1981 • 292 citations

Aggregation of complement receptors on human neutrophils in the absence of ligand.

1987 • 250 citations

Subcellular localization of the large subunit of Mo1 (Mo1 alpha; formerly gp 110), a surface glycoprotein associated with neutrophil adhesion.

1984 • 249 citations

An Arg-Gly-Asp-directed receptor on the surface of human melanoma cells exists in an divalent cation-dependent functional complex with the disialoganglioside GD2.

1987 • 246 citations

A novel calcium binding site in the galactose-binding protein of bacterial transport and chemotaxis

1987 • 238 citations

Phorbol esters cause sequential activation and deactivation of complement receptors on polymorphonuclear leukocytes.

1986 • 206 citations

Macrophage-lymphocyte interaction. II. Antigen-mediated physical interactions between immune guinea pig lymph node lymphocytes and syngeneic macrophages.

1975 • 194 citations

Integrin (alpha v beta 3)-ligand interaction. Identification of a heterodimeric RGD binding site on the vitronectin receptor.

1990 • 193 citations

The specific interaction of helper T cells and antigen-presenting B cells. IV. Membrane and cytoskeletal reorganizations in the bound T cell as a function of antigen dose.

1989 • 166 citations

Dissociation between increased surface expression of gp165/95 and homotypic neutrophil aggregation.

1988 • 156 citations

The leukocyte integrins

1989 • 135 citations

Role of the LFA-1 molecule in cellular interactions required for antibody production in humans.

1986 • 105 citations

Analysis of the Expression and Function of Class-II Major Histocompatibility Complex-Encoded Molecules by DNA-Mediated Gene Transfer

1986 • 96 citations

Human memory T cells express intercellular adhesion molecule‐1 which can be increased by interleukin 2 and interferon‐γ

1990 • 84 citations

The role of monocyte lymphocyte function‐associated antigen 1 (LFA‐1) in accessory cell function

1987 • 77 citations

Morphological changes, cell aggregation and cell membrane alterations caused by phorbol 12,13-dibutyrate in human blood lymphocytes

1982 • 56 citations

Lateral diffusion measurements give evidence for association of the Tac peptide of the IL-2 receptor with the T27 peptide in the plasma membrane of HUT-102-B2 T cells.

1988 • 52 citations

An anti-human monocyte/macrophage monoclonal antibody, reacting most strongly with macrophages in lymphoid tissue

1985 • 47 citations

Leukocyte Adhesion Molecules

1990 • 39 citations

Differential effects of monoclonal antibodies anti-L3T4 and anti-LFA1 on the antigen-induced proliferation of T-helper-cell clones: Correlation between their susceptibility to inhibition and their affinity for antigen

1985 • 23 citations