Activation of lymphokine genes during stimulation of cloned T cells

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

[18] Hybridization of denatured RNA transferred or dotted to nitrocellulose paper

1983 • 1,112 citations

Transient expression of interleukin 2 receptors. Consequences for T cell growth.

1983 • 613 citations

Triggering of the T3-Ti antigen-receptor complex results in clonal T-cell proliferation through an interleukin 2-dependent autocrine pathway.

1984 • 506 citations

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO

1974 • 488 citations

Cloning and expression of murine immune interferon cDNA.

1983 • 455 citations

Interleukin-2 stimulates association of protein kinase C with plasma membrane

1985 • 384 citations

Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells.

1984 • 365 citations

A procedure for removing red cells and dead cells from lymphoid cell suspensions

1975 • 303 citations

Sequential expression of genes involved in human T lymphocyte growth and differentiation.

1985 • 291 citations

Alloreactive cloned T cell lines. I. Interactions between cloned amplifier and cytolytic T cell lines.

1980 • 235 citations

Activation of a human T cell line: a two-stimulus requirement in the pretranslational events involved in the coordinate expression of interleukin 2 and gamma-interferon genes.

1985 • 203 citations

Use of a cDNA expression vector for isolation of mouse interleukin 2 cDNA clones: expression of T-cell growth-factor activity after transfection of monkey cells.

1985 • 178 citations

Generation of cytolytic T lymphocytes in vitro. IX. induction of secondary CTL responses in primary long-term MLC by supernatants from secondary MLC.

1978 • 166 citations

Alloreactive cloned T cell lines. VI. Multiple lymphokine activities secreted by helper and cytolytic cloned T lymphocytes.

1982 • 145 citations

Production of macrophage-activating factor by T lymphocyte clones and correlation with other lymphokine activities.

1982 • 142 citations

Control of biologically active interleukin 2 messenger RNA formation in induced human lymphocytes.

1984 • 141 citations

Murine T Lymphocyte Clones with Distinct Immunological Functions

1981 • 133 citations

Antigenic stimulation regulates the level of expression of interleukin 2 receptor on human T cells.

1984 • 120 citations

Kinetics of induction and molecular size of mRNAs encoding human interleukin-2 and γ-interferon

1982 • 104 citations

Regulation of IFN-gamma induction in human peripheral blood cells by exogenous and endogenously produced interleukin 2.

1985 • 96 citations

Generation of Cytolytic T Lymphocytes in Vitro

1978 • 73 citations

A clone-specific monoclonal antibody that inhibits cytolysis of a cytolytic T cell clone.

1983 • 59 citations

Alloreactive cloned T cell lines. V. Differential kinetics of IL 2, CSF, and BCSF release by a cloned T amplifier cell and its variant.

1981 • 58 citations

An antigen receptor-driven, interleukin 2-independent pathway for proliferation of murine cytolytic T lymphocyte clones.

1986 • 58 citations

Antigen-reactive cloned helper T cells. II. Exposure of murine cloned helper T cells to IL 2-containing supernatant induces unresponsiveness to antigenic restimulation and inhibits lymphokine production after antigenic stimulation.

1984 • 51 citations

Interleukin 2 enhancement of lymphokine secretion by T lymphocytes: analysis of established clones and primary limiting dilution microcultures.

1984 • 48 citations

Superinduction of human interleukin-2 messenger RNA by inhibitors of translation

1984 • 47 citations

Changes in levels of actin and tubulin mRNAs upon the lectin activation of lymphocytes.

1984 • 36 citations

5-Azacytidine treatment of a murine cytotoxic T cell line alters interferon-gamma gene induction by interleukin 2.

1985 • 27 citations

Interleukin 2-dependent release of interleukin 3 activity by T4+ human T-cell clones.

1985 • 27 citations

Alloreactive cloned T cell lines. VII. Comparison of the kinetics of IL 2 release stimulated by alloantigen or Con A.

1983 • 10 citations

A qualitative difference in the interleukin 2 (IL-2) requirement of helper and cytotoxic T lymphocytes

1984 • 4 citations