Chronic parasite infections cause immune changes that could affect successful vaccination

Immune activation is a dominant factor in the pathogenesis of African AIDS

1995 • 375 citations

Effect of deworming on human T cell responses to mycobacterial antigens in helminth-exposed individuals before and after bacille Calmette–Guérin (BCG) vaccination

2001 • 323 citations

Can eradication of helminthic infections change the face of AIDS and tuberculosis?

1999 • 230 citations

Human Infection withAscaris lumbricoidesIs Associated with Suppression of the Interleukin-2 Response to Recombinant Cholera Toxin B Subunit following Vaccination with the Live Oral Cholera Vaccine CVD 103-HgR

2001 • 229 citations

Impaired Tetanus‐Specific Cellular and Humoral Responses following Tetanus Vaccination in Human Onchocerciasis: A Possible Role for Interleukin‐10

1998 • 178 citations

Chronic Immune Activation Associated with Chronic Helminthic and Human Immunodeficiency Virus Infections: Role of Hyporesponsiveness and Anergy

2004 • 140 citations

Non-human primates: a model for tuberculosis research

2003 • 125 citations

Impairment of Tetanus-Specific Cellular and Humoral Responses following Tetanus Vaccination in Human Lymphatic Filariasis

2004 • 116 citations

Helminth Infection Is Not Associated with Faster Progression of HIV Disease in Coinfected Adults in Uganda

2004 • 111 citations

CTLA-4 in Filarial Infections: Implications for a Role in Diminished T Cell Reactivity

2003 • 109 citations

Infection with parasitic nematodes confounds vaccination efficacy

2007 • 96 citations

Associations between helminth infection and CD4+ T cell count, viral load and cytokine responses in HIV-1-infected Ugandan adults

2003 • 91 citations

Reduced Protective Efficacy of a Blood-Stage Malaria Vaccine by Concurrent Nematode Infection

2006 • 90 citations

HIV/AIDS: in search of an animal model

2007 • 83 citations

HIV and helminth co‐infection: is deworming necessary?

2006 • 79 citations

Human Onchocerciasis and Tetanus Vaccination: Impact on the Postvaccination Antitetanus Antibody Response

1999 • 73 citations

Treatment of Intestinal Helminths Does Not Reduce Plasma Concentrations of HIV‐1 RNA in Coinfected Zambian Adults

2005 • 68 citations

COINCIDENT FILARIAL, INTESTINAL HELMINTH, AND MYCOBACTERIAL INFECTION: HELMINTHS FAIL TO INFLUENCE TUBERCULIN REACTIVITY, BUT BCG INFLUENCES HOOKWORM PREVALENCE

2006 • 46 citations

HIV and Parasitic Infection and the Effect of Treatment among Adult Outpatients in Malawi

2007 • 46 citations

Treatment of Helminth Co-Infection in Individuals with HIV-1: A Systematic Review of the Literature

2007 • 41 citations

Effect of Diethylcarbamazine on HIV Load, CD4%, and CD4/CD8 Ratio in HIV-Infected Adult Tanzanians with or without Lymphatic Filariasis: Randomized Double-Blind and Placebo-Controlled Cross-Over Trial

2007 • 38 citations

Host Background Immunity and Human Immunodeficiency Virus Protective Vaccines, a Major Consideration for Vaccine Efficacy in Africa and in Developing Countries

2002 • 29 citations

Generation of Th1 immune responses to inactivated, gp120-depleted HIV-1 in mice with a dominant Th2 biased immune profile via imunostimulatory oligonucleotides—relevance to AIDS vaccines in developing countries

2002 • 27 citations

A novel small animal model for HIV‐1 infection

2005 • 12 citations

Evolution, Benefits, and Shortcomings of Vaccine Management

2007 • 11 citations