Characterization of tumour necrosis factor α release by human granulocytes in response to procainamide challenge

The Biology of Cachectin/TNF -- A Primary Mediator of the Host Response

1989 • 1,679 citations

CYTOKINES: COORDINATORS OF IMMUNE AND INFLAMMATORY RESPONSES

1990 • 1,304 citations

Single-step separation of red blood cells, granulocytes and mononuclear leukocytes on discontinuous density gradients of Ficoll-Hypaque

1974 • 735 citations

Gel electrophoresis: Proteins

1997 • 732 citations

Fluorometric method for rapid detection of DNA strand breaks in human white blood cells produced by low doses of radiation.

1981 • 448 citations

The active form of tumor necrosis factor is a trimer.

1987 • 430 citations

Effect of Acetylator Phenotype on the Rate at Which Procainamide Induces Antinuclear Antibodies and the Lupus Syndrome

1978 • 382 citations

Endogenous circulating DNA in systemic lupus erythematosus. Occurrence as multimeric complexes bound to histone.

1990 • 367 citations

Human histocompatibility antigen associations in subacute cutaneous lupus erythematosus.

1981 • 120 citations

Nucleosomes and DNA bind to specific cell-surface molecules on murine cells and induce cytokine production

1992 • 114 citations

Analysis of TNF alpha-induced DNA strand breaks at the single cell level.

1991 • 111 citations

Reactivity and possible significance of hydroxylamine and nitroso metabolites of procainamide.

1985 • 96 citations

Drug-induced Lupus: Clinical and Serological Studies

1982 • 95 citations

Effects of long-term treatment with procaine amide. A prospective study with special regard to ANF and SLE in fast and slow acetylators.

1975 • 93 citations

Systemic Lupus Erythematosus. STUDIES OF THE ANTIBODIES BOUND TO SKIN

1973 • 92 citations

Effects of Long‐term Treatment with Procaine Amide

1975 • 86 citations

Carbamazepine metabolism to a reactive intermediate by the myeloperoxidase system of activated neutrophils

1993 • 78 citations

Autoimmunity induced by chemicals

1988 • 77 citations

Isoniazid Induction of Antinuclear Antibodies

1978 • 70 citations

Metabolism of procainamide to a hydroxylamine by human neutrophils and mononuclear leukocytes

1988 • 66 citations

Acetylprocainamide Therapy in Patients with Previous Procainamide-Induced Lupus Syndrome

1981 • 63 citations

Crystallization of trimeric recombinant human tumor necrosis factor (cachectin).

1988 • 48 citations

Cytotoxicity of oxidative metabolites of procainamide.

1987 • 48 citations

N-chlorination of phenytoin by myeloperoxidase to a reactive metabolite

1988 • 45 citations

Metabolism of procainamide to the cytotoxic hydroxylamine by neutrophils activated in vitro.

1989 • 42 citations

N-Chlorination and oxidation of procainamide by myeloperoxidase: toxicological implications

1991 • 40 citations

Gel electrophoresis: Proteins

1994 • 35 citations

Increased DNA strand breaks in mononuclear cells from patients with rheumatoid arthritis.

1992 • 31 citations

Comparative metabolism and covalent binding of procainamide by human leukocytes.

1992 • 18 citations

Analysis of internucleosomal DNA fragmentation in apoptotic thymocytes by dynamic sieving capillary electrophoresis

1995 • 17 citations

Role of ultraviolet light and UV DNA in the induction of skin lesions in experimental animals

1978 • 13 citations

TUMOR-NECROSIS-FACTOR-ALPHA INDUCES APOPTOSIS IN HUMAN LEUKEMIA T-CELL LINE MOLT-16 - ITS RELATION TO BCL-2 AND C-MYC EXPRESSION

1994 • 3 citations