Influence of aging on T-cell subpopulations involved in the in vitro generation of allogeneic cytotoxicity

Functional subclasses of T lymphocytes bearing different Ly antigens. II. Cooperation between subclasses of Ly+ cells in the generation of killer activity.

1975 • 758 citations

GENERATION OF CYTOTOXIC T LYMPHOCYTES IN VITRO

1974 • 488 citations

Augmentation of delayed-type hypersensitivity by doses of cyclophosphamide which do not affect antibody responses.

1975 • 434 citations

Immunoregulatory circuits among T-cell sets. I. T-helper cells induce other T-cell sets to exert feedback inhibition.

1978 • 424 citations

Cyclophosphamide-sensitive T lymphocytes suppress the in vivo generation of antigen-specific cytotoxic T lymphocytes

1977 • 337 citations

ISOLATION, BIOCHEMICAL CHARACTERISTICS, AND BIOLOGICAL ACTIVITY OF A CIRCULATING THYMIC HORMONE IN THE MOUSE AND IN THE HUMAN

1975 • 288 citations

Immunological studies of aging. II. Loss of IgG and high avidity plaque-forming cells and increased suppressor cell activity in aging mice.

1976 • 239 citations

Biochemical characterisation of a serum thymic factor

1977 • 227 citations

Studies on thymus products. II. Demonstration and characterization of a circulating thymic hormone.

1973 • 151 citations

T-T interactions in the induction of suppressor and helper T cells: analysis of membrane phenotype of precursor and amplifier cells.

1977 • 144 citations

SYNERGY DURING IN VITRO CYTOTOXIC ALLOGRAFT RESPONSES

1973 • 137 citations

Humoral immunity in aged mice. II. Increased suppressor T cell activity in immunologically deficient old mice.

1976 • 124 citations

Immunobiology of aging: Evaluation of current status

1976 • 115 citations

Regulation of the immune response by subclasses of T lymphocytes. I. Interactions between pre‐killer T cells and regulatory T cells obtained from peripheral lymphoid tissues of mice

1975 • 108 citations

Induction of Specific Suppressor T Cells in Vitro

1976 • 105 citations

Decline in Mixed Lymphocyte Reactivity of Spleen Cells from Aged Mice of a Long-Lived Strain

1973 • 99 citations

Age-Related Changes in T Cell Function

1977 • 85 citations

Age-Related Changes in Cell-Mediated Immunity in BALB/C Mice

1975 • 82 citations

Generation of Cytotoxic T Lymphocytes in Vitro VII. Suppressive Effect of Irradiated MLC Cells on CTL Response

1976 • 79 citations

Reduced humoral immune activity in long-lived old mice: an approach to elucidating its mechanisms.

1976 • 69 citations

Autoimmunity and Aging: The Age-Related Response of Mice of a Long-Lived Strain to Trinitrophenylated Syngeneic Mouse Red Blood Cells

1976 • 56 citations

Cell-mediated immune response in vitro. II. The mechanism(s) involved in the suppression of the development of cytotoxic lymphocytes.

1976 • 37 citations

Age-related changes in the cellular immune response of lymph node and thymus cells in long-lived mice

1975 • 32 citations

Generation of cytotoxic T lymphocytes in vitro. VI. Effect of cell density on response in mixed leukocyte cultures.

1975 • 23 citations

Regulation of cell-mediated cytotoxicity

1975 • 7 citations