PDZ domain of neuronal nitric oxide synthase recognizes novel C-terminal peptide sequences

The L-Arginine-Nitric Oxide Pathway

1993 • 6,737 citations

A novel genetic system to detect protein–protein interactions

1989 • 6,022 citations

Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

1988 • 2,572 citations

Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

1991 • 2,371 citations

NITRIC OXIDE: A Physiologic Messenger Molecule

1994 • 2,299 citations

Domain Interaction Between NMDA Receptor Subunits and the Postsynaptic Density Protein PSD-95

1995 • 1,861 citations

Nitric Oxide Signaling in the Central Nervous System

1995 • 1,628 citations

Interaction of Nitric Oxide Synthase with the Postsynaptic Density Protein PSD-95 and α1-Syntrophin Mediated by PDZ Domains

1996 • 1,589 citations

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

1994 • 1,578 citations

Nitric oxide synthase structure and mechanism

1993 • 1,342 citations

The rat brain postsynaptic density fraction contains a homolog of the drosophila discs-large tumor suppressor protein

1992 • 1,180 citations

Applications of Combinatorial Technologies to Drug Discovery. 1. Background and Peptide Combinatorial Libraries

1994 • 1,130 citations

Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ

1996 • 1,127 citations

Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases

1995 • 994 citations

Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy

1995 • 954 citations

A novel neuronal messenger molecule in brain: The free radical, nitric oxide

1992 • 837 citations

Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases

1996 • 735 citations

PIN: An Associated Protein Inhibitor of Neuronal Nitric Oxide Synthase

1996 • 454 citations

Inhibition of neuronal nitric oxide synthase prevents MPTP–induced parkinsonism in baboons

1996 • 422 citations

SAP102, a Novel Postsynaptic Protein That Interacts with NMDA Receptor Complexes In Vivo

1996 • 422 citations

Cloning and Characterization of Postsynaptic Density 93, a Nitric Oxide Synthase Interacting Protein

1996 • 327 citations

PDZs and Receptor/Channel Clustering: Rounding Up the Latest Suspects

1996 • 322 citations

Crystal structure of a PDZ domain

1996 • 315 citations

Binding of the Inward Rectifier K+ Channel Kir 2.3 to PSD-95 Is Regulated by Protein Kinase A Phosphorylation

1996 • 265 citations

Clustering Membrane Proteins: It's All Coming Together with the PSD-95/SAP90 Protein Family

1996 • 246 citations

Screening for receptor ligands using large libraries of peptides linked to the C terminus of the lac repressor.

1992 • 178 citations

Selective loss of sarcolemmal nitric oxide synthase in Becker muscular dystrophy.

1996 • 158 citations

Nitric oxide synthase in the visual cortex of monocular monkeys as revealed by light and electron microscopic immunocytochemistry

1993 • 123 citations

The Human ∆1261 Mutation of the HERG Potassium Channel Results in a Truncated Protein That Contains a Subunit Interaction Domain and Decreases the Channel Expression

1997 • 93 citations

Associative properties of the Escherichiacoli galactose binding protein and maltose binding protein

1982 • 42 citations

[10] Screening of peptide libraries linked to lac repressor

1996 • 39 citations

[35] SH2 domain specificity determination using oriented phosphopeptide library

1995 • 38 citations

Melatonin enhances guanylate cyclase activity in a variety of tissues

1981 • 25 citations

[50] Screening phage-displayed random peptide libraries for SH3 ligands

1995 • 25 citations