Increased Protein Kinase C Activity in Fibroblast Membranes From Psoriatic Patients

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Turnover of Inositol Phospholipids and Signal Transduction

1984 • 1,629 citations

Calcium-activated, phospholipid-dependent protein kinase from rat brain. Subcellular distribution, purification, and properties.

1982 • 1,008 citations

Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH

1984 • 447 citations

Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 cells: role of Ca2+-sensitive phospholipid-dependent protein kinase.

1984 • 266 citations

sn-1,2-Dioctanoylglycerol. A cell-permeable diacylglycerol that mimics phorbol diester action on the epidermal growth factor receptor and mitogenesis.

1985 • 179 citations

Protein kinase C in fibroblasts. Characteristics of its intracellular location during growth and after exposure to phorbol esters and other mitogens.

1987 • 127 citations

Phosphorylation of the glucose transporter in vitro and in vivo by protein kinase C

1985 • 126 citations

Decreased Protein Kinase C Activity in Psoriatic Versus Normal Epidermis

1987 • 123 citations

Comparison of mode of activation of guanosine 3':5'-monophosphate-dependent and adenosine 3':5'-monophosphate-dependent protein kinases from silkworm.

1976 • 109 citations

Altered subcellular distribution of protein kinase C (a phorbol ester receptor). Possible role in tumor promotion and the regulation of cell growth: relationship to changes in adenylate cyclase activity.

1985 • 88 citations

Hyperactivity of fibroblasts cultured from psoriatic skin: I. Faster proliferation and effect of serum withdrawal

1983 • 55 citations

Deficiency of cyclic AMP-dependent protein kinases in human psoriasis.

1986 • 49 citations

Proliferating and quiescent cells exhibit different subcellular distribution of protein kinase C activity

1986 • 26 citations

Mitogenic effects of sera from normal and psoriatic subjects on human skin fibroblasts

1984 • 11 citations

Is the dermal fibroblast significant in psoriasis?

1986 • 2 citations