Hypoxia-specific Inhibition of Recovery from Radiation Damage by a Novel 2-nitroimidazole with a Theophylline Side Chain

International Journal of Radiation Biology

1959 • 1,730 citations

Intermittent blood flow in a murine tumor: radiobiological effects.

1987 • 440 citations

Acute hypoxia in tumors: Implications for modifiers of radiation effects

1986 • 267 citations

British journal of cancer

1978 • 187 citations

Reduced Oxygen Enhancement Ratio at Low Doses of Ionizing Radiation

1984 • 179 citations

Chemical sensitizers for hypoxic cells: A decade of experience in clinical radiotherapy

1985 • 177 citations

The use of fluorescent probes to identify regions of transient perfusion in murine tumors

1989 • 173 citations

The Action of Caffeine on X-Irradiated HeLa Cells: III. Enhancement of X-Ray-Induced Killing during G 2 Arrest

1978 • 160 citations

Misonidazole—A drug for trial in radiotherapy and oncology

1979 • 132 citations

Studies on the Toxicity and Radiosensitizing Ability of Misonidazole under Conditions of Prolonged Incubation

1978 • 127 citations

Caffeine Enhancement of X-Ray Killing in Cultured Human and Rodent Cells

1978 • 103 citations

Ro-07-0582 as a radiosensitizer and cytotoxic agent

1977 • 89 citations

Enhancement of Misonidazole Radiosensitization by an Inhibitor of Glutathione Biosynthesis

1983 • 81 citations

Survival measurements at low doses: oxygen enhancement ratio

1982 • 78 citations

Flow cytometric evaluation of hypoxic cells in solid experimental tumours using fluorescence immunodetection

1991 • 73 citations

Keynote address: Hypoxic cell radiosensitizers: Where next?

1989 • 71 citations

HYPOXIC CELL SENSITISERS IN RADIOTHERAPY

1976 • 64 citations

Radiosensitization of Chinese Hamster Cells by Oxygen and Misonidazole at Low X-ray Doses

1986 • 62 citations

Override of the Radiation-induced Mitotic Block in Human Tumour Cells by Methylxanthines and Its Relationship to the Potentiation of Cytotoxicity

1990 • 49 citations

Final report of the phase i trial of the hypoxic cell radiosensitizer SR 2508 (etanidazole) radiation therapy oncology group 83-03

1990 • 44 citations

The Effect of Misonidazole as a Hypoxic Radiosensitizer at Low Dose

1984 • 40 citations

An Efficient Procedure for the 1-Alkylation of 2-Nitroimidazoles and the Synthesis of a Probe for Hypoxia in Solid Tumours

1991 • 33 citations

Radiosensitization of hypoxic cells at low doses

1986 • 30 citations

Fluorescent markers for hypoxic cells: a comparison of two compounds on three cell lines

1985 • 27 citations

Effects of glutathione depletion using buthionine sulphoximine on the cytotoxicity of nitroaromatic compounds in mammalian cells in vitro

1985 • 25 citations

The nitroimidazoles as radiosensitizers and cytotoxic agents.

1978 • 23 citations

Caffeine-induced modulation of the lethal action of X rays on Chinese hamster V79 cells.

1988 • 20 citations

Competitive Dose-modification between Ascorbate and Misonidazole in Human and Hamster Cells: Effects of Glutathione Depletion

1988 • 17 citations

Caffeine-Induced Modulation of the Lethal Action of X Rays on Chinese Hamster V79 Cells

1988 • 15 citations

A comparison of two nitroimidazoles and a dihydroquinoline as radiosensitizers and cytotoxic agents

1979 • 12 citations

Inhibition of X-Ray-Induced Potentially Lethal Damage (PLD) Repair in Aerobic Plateau-Phase Chinese Hamster Cells by Misonidazole

1984 • 11 citations

Radiosensitization of Chinese hamster cells by pimonidazole (Ro 03–8799) at low X-ray doses

1991 • 4 citations