Enhancer sequences of a retroviral vector determine expression of a gene in multipotent hematopoietic progenitors and committed erythroid cells.

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene

1983 • 1,418 citations

Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production

1986 • 1,276 citations

Nucleotide sequence of Moloney murine leukaemia virus

1981 • 1,079 citations

Construction and applications of a highly transmissible murine retrovirus shuttle vector

1984 • 1,020 citations

A cDNA cloning vector that permits expression of cDNA inserts in mammalian cells.

1983 • 933 citations

Developmental potential and dynamic behavior of hematopoietic stem cells

1986 • 888 citations

Factors regulating macrophage production and growth. Purification and some properties of the colony stimulating factor from medium conditioned by mouse L cells.

1977 • 740 citations

Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, P cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity

1983 • 702 citations

Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/W mice

1985 • 663 citations

Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility

1987 • 619 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells.

1986 • 533 citations

High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range.

1984 • 407 citations

Negative regulation of viral enhancers in undifferentiated embryonic stem cells

1985 • 347 citations

Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene.

1985 • 342 citations

Gene Expression in Mice After High Efficiency Retroviral-Mediated Gene Transfer

1985 • 281 citations

Immunoglobulin Heavy-Chain Enhancer Requires One or More Tissue-Specific Factors

1985 • 271 citations

Non-function of a Moloney murine leukaemia virus regulatory sequence in F9 embryonal carcinoma cells

1984 • 258 citations

Role for the 3' end of the genome in determining disease specificity of Friend and Moloney murine leukemia viruses.

1983 • 246 citations

Sensitivity of corticosteroid-dependent insulin-resistant lipogenesis in marrow preadipocytes of obese-diabetic (db/db) mice

1978 • 231 citations

Retrovirus transfer of a bacterial gene into mouse haematopoietic progenitor cells

1983 • 214 citations

Retrovirus-mediated transfer and expression of drug resistance genes in human haematopoietic progenitor cells

1986 • 213 citations

Thymotropism of murine leukemia virus is conferred by its long terminal repeat.

1983 • 209 citations

Factors involved in production of helper virus-free retrovirus vectors

1986 • 181 citations

A 3' end fragment encompassing the transcriptional enhancers of nondefective Friend virus confers erythroleukemogenicity on Moloney leukemia virus

1984 • 171 citations

Disease specificity of nondefective Friend and Moloney murine leukemia viruses is controlled by a small number of nucleotides

1987 • 164 citations

Nucleotide sequence of the envelope gene of Friend murine leukemia virus

1983 • 140 citations

Generation of Helper-Free Amphotropic Retroviruses That Transduce a Dominant-Acting, Methotrexate-Resistant Dihydrofolate Reductase Gene

1985 • 125 citations

Granulopoiesis Longevity in Continuous Bone Marrow Cultures and Factor-Dependent Cell Line Generation: Significant Variation Among 28 Inbred Mouse Strains and Outbred Stocks<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1982 • 83 citations

Characterization of a primitive erythropoietic progenitor found in mouse marrow before and after several weeks in culture

1979 • 78 citations

Magic Enhancers?

1984 • 70 citations

Gene transfer to primary normal and malignant human hemopoietic progenitors using recombinant retroviruses

1987 • 69 citations

A transcriptional enhancer with specificity for erythroid cells is located in the long terminal repeat of the Friend murine leukemia virus.

1986 • 55 citations

Tissue tropism of a leukemogenic murine retrovirus is determined by sequences outside of the long terminal repeats.

1986 • 28 citations

Perspectives for gene therapy: Inserting new genetic information into mammalian cells by physical techniques and viral vectors

1985 • 27 citations

Expression of a selectable gene transferred by a retroviral vector to hematopoietic stem cells and stromal cells in murine continuous bone marrow cultures.

1987 • 25 citations