Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney

Elevated Circulating Levels of Tumor Necrosis Factor in Severe Chronic Heart Failure

1990 • 2,566 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

1995 • 1,311 citations

Rapid colormetric assay for cell viability: Application to the quantitation of cytotoxic and growth inhibitory lymphokines

1984 • 561 citations

Renal injury from angiotensin II-mediated hypertension.

1992 • 546 citations

Angiotensin II and Renal Fibrosis

2001 • 503 citations

Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level.

1990 • 495 citations

Transcription factor-κB (NF-κB) and renal disease

2001 • 474 citations

Detection and localization of tumor necrosis factor in human atheroma

1990 • 453 citations

Tumor necrosis factor-alpha gene and protein expression in adult feline myocardium after endotoxin administration.

1995 • 436 citations

Proinflammatory actions of angiotensins

2001 • 409 citations

Angiotensin II Induces Interleukin-6 Transcription in Vascular Smooth Muscle Cells Through Pleiotropic Activation of Nuclear Factor-κB Transcription Factors

1999 • 374 citations

Identification of cyclophilin as a proinflammatory secretory product of lipopolysaccharide-activated macrophages.

1992 • 354 citations

Angiotensin II as a renal growth factor.

1993 • 311 citations

Renoprotective effects of angiotensin II receptor blockade in type 1 diabetic patients with diabetic nephropathy

2000 • 285 citations

Angiotensin II participates in mononuclear cell recruitment in experimental immune complex nephritis through nuclear factor-kappa B activation and monocyte chemoattractant protein-1 synthesis.

1998 • 285 citations

Hemodynamic Regulation of Tumor Necrosis Factor-α Gene and Protein Expression in Adult Feline Myocardium

1997 • 284 citations

Preactivated Peripheral Blood Monocytes in Patients With Essential Hypertension

1999 • 266 citations

Biologic activities and mechanisms of action of tumor necrosis factor-alpha/cachectin.

1991 • 256 citations

Angiotensin II stimulates expression of the chemokine RANTES in rat glomerular endothelial cells. Role of the angiotensin type 2 receptor.

1997 • 255 citations

Angiotensin II Participates in Mononuclear Cell Recruitment in Experimental Immune Complex Nephritis Through Nuclear Factor-κB Activation and Monocyte Chemoattractant Protein-1 Synthesis

1998 • 226 citations

Production of tumor necrosis factor by rat mesangial cells in response to bacterial lipopolysaccharide

1989 • 220 citations

Systemic Infusion of Angiotensin II into Normal Rats Activates Nuclear Factor-κB and AP-1 in the Kidney

2001 • 180 citations

Role of TNFR1 and TNFR2 receptors in tubulointerstitial fibrosis of obstructive nephropathy

1999 • 139 citations

Presence of tumor necrosis factor alpha and interleukin-6 in renal mesangial cells of lupus nephritis patients

1995 • 127 citations

Do ACE‐inhibitors suppress tumour necrosis factor‐α production in advanced chronic renal failure?

1999 • 119 citations

Genes for IFN-beta-2 (IL-6), tumor necrosis factor, and IL-1 are expressed at high levels in the organs of normal individuals.

1988 • 119 citations

Angiotensin III increases MCP-1 and activates NF-кB and AP-1 in cultured mesangial and mononuclear cells

2000 • 114 citations

Angiotensin II and mechanical stretch induce production of tumor necrosis factor in cardiac fibroblasts

1999 • 111 citations

Expression of Tumor Necrosis Factor-α in Cultured Human Endothelial Cells Stimulated With Lipopolysaccharide or Interleukin-1α

2000 • 109 citations

Angiotensin II induces TNF production by the thick ascending limb: functional implications

1998 • 100 citations

Angiotensin II stimulates interleukin-6 release from cultured mouse mesangial cells.

1995 • 100 citations

Tumor necrosis factor-alpha is expressed by glomerular visceral epithelial cells in human membranous nephropathy.

1995 • 96 citations

Osteopontin expression in progressive renal injury in remnant kidney: Role of angiotensin II

2000 • 90 citations

Angiotensin converting enzyme inhibitors suppress production of tumor necrosis factor-α in vitro and in vivo

1997 • 88 citations

Enalapril protects mice from pulmonary hypertension by inhibiting TNF-mediated activation of NF-κB and AP-1

2002 • 69 citations

Tumor necrosis factor-α-angiotensin interactions and regulation of blood pressure

1997 • 62 citations

EFFECT OF β2-ADRENOCEPTOR ACTIVATION AND ANGIOTENSIN II ON TUMOUR NECROSIS FACTOR AND INTERLEUKIN 6 GENE TRANSCRIPTION IN THE RAT RENAL RESIDENT MACROPHAGE CELLS

1999 • 59 citations

Angiotensin II Increases Parathyroid Hormone-Related Protein (PTHrP) and the Type 1 PTH/PTHrP Receptor in the Kidney

2002 • 59 citations

Molecular regulation of tumor necrosis factor-alpha and lymphotoxin production in T cells. Inhibition by prostaglandin E2.

1992 • 56 citations

Expression of leucocyte chemoattractants by interstitial renal fibroblasts: up-regulation by drugs associated with interstitial fibrosis

1996 • 53 citations

Tumour necrosis factor is expressed in cardiac tissues of patients with heart failure

1996 • 52 citations

Fractalkine expression and the recruitment of CX3CR1+ cells in the prolonged mesangial proliferative glomerulonephritis

2002 • 52 citations

Suppression of Endotoxin-Induced Renal Tumor Necrosis Factor-α and Interleukin-6 mRNA by Renin-Angiotensin System Inhibitors

2002 • 29 citations

The intercrine superfamily and renal disease.

1993 • 24 citations

Biology of the Mesangial Cell in Glomerulonephritis-Role of Cytokines

1996 • 21 citations

Cyclosporin A (CsA) modulates the glomerular production of inflammatory mediators and proteoglycans in experimental nephrosis

1995 • 16 citations

Cyclophilin B Expression in Renal Proximal Tubules of Hypertensive Rats

2000 • 13 citations