Long-term effects of exposure of pancreatic islets to nicotinamide in vitro on DNA synthesis, metabolism and B-cell function

Untersuchungen uber die Harnstoffbildung im Tierkörper

1932 • 3,104 citations

The Fluorometric Measurement of Deoxyribonucleic Acid in Animal Tissues with Special Reference to the Central Nervous System

1958 • 1,786 citations

An improved fluorometric assay for DNA

1971 • 997 citations

Poly(ADP-Ribose) in the Cellular Response to DNA Damage

1985 • 771 citations

Determination of total serum insulin (IRI) in insulin-treated diabetic patients

1972 • 707 citations

Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets

1981 • 530 citations

Potassium ions and the secretion of insulin by islets of Langerhans incubated in vitro

1968 • 301 citations

Isolated mouse pancreatic islets in culture: Effects of serum and different culture media on the insulin production of the islets

1978 • 287 citations

Inhibitors of Poly(Adenosine Diphosphate-Ribose) Synthesis: Effect on Other Metabolic Processes

1984 • 241 citations

Amelioration of Diabetes Mellitus in Partially Depancreatized Rats by Poly(ADP-ribose) Synthetase Inhibitors: Evidence of Islet B-Cell Regeneration

1984 • 161 citations

Interrelationship between poly (ADP-Rib) synthesis, intracellular NAD levels, and muscle or cartilage differentiation from mesodermal cells of embryonic chick limb.

1975 • 158 citations

Mechanisms of streptozotocin- and alloxan-induced damage in rat B cells

1984 • 130 citations

Molecular basis of experimental diabetes: Degeneration, oncogenesis and regeneration of pancreatic B‐cells of islets of Langerhans

1985 • 110 citations

Streptozotocin, but not alloxan, induces DNA repair synthesis in mouse pancreatic islets in vitro

1983 • 82 citations

Effect of Poly(ADP-ribose) Synthetase Inhibitor Administration to Rats Before and After Injection of Alloxan and Streptozotocin on Islet Proinsulin Synthesis

1983 • 81 citations

Effect of genetic background on the capacity for islet cell replication in mice

1984 • 81 citations

Anti-Insulin Serum Coupled to Sepharose 4B as a Tool for the Investigation of Insulin Biosynthesis in the B-Cells of Obese Hyperglycemic Mice

1975 • 60 citations

On the mechanism of preadipocyte differentiation. Masking of poly(ADP-ribose) synthetase activity during differentiation of 3T3-L1 preadipocytes.

1981 • 59 citations

Long-term effects of glucose on insulin release and glucose oxidation by mouse pancreatic islets maintained in tissue culture

1974 • 53 citations

Involvement of poly(ADP-ribose) metabolism in induction of differentiation of HL-60 promyelocytic leukemia cells

1982 • 50 citations

Streptozotocin‐induced Impairment of Islet B‐Cell Metabolism and its Prevention by a Hydroxyl Radical Scavenger and Inhibitors of Poly(ADP‐ribose) synthetase

1983 • 48 citations

Nicotinamide methylation and its relation to NAD synthesis in rat liver tissue cultureBiochemical basis fro the physiological activities of 1-methylnicotinamide

1984 • 26 citations

Nicotinamide Modulation of Rat Pancreatic Islet Cell Responsiveness In Vitro

1979 • 10 citations

Dissociation between insulin secretion and DNA synthesis in cultured pancreatic islets.

1985 • 6 citations

DNA repair synthesis in the pancreatic islets of streptozotocin-treated mice.

1985 • 6 citations

Potentialities of Bioluminescence Analyses in Research on the Pancreatic Islets

1981 • 1 citations