N-Acetylcysteine reduces respiratory burst but augments neutrophil phagocytosis in intensive care unit patients

APACHE II-A Severity of Disease Classification System

1986 • 12,607 citations

APACHE II

1985 • 12,347 citations

American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference

1992 • 4,689 citations

Treating Patients with Severe Sepsis

1999 • 1,006 citations

Oxygen Metabolism and the Toxic Properties of Phagocytes

1980 • 886 citations

Pulmonary Strategies of Antioxidant Defense

1989 • 551 citations

A Trial of Antioxidants N-acetylcysteine and Procysteine in ARDS

1997 • 409 citations

Pharmacokinetics of N-acetylcysteine in man

1986 • 333 citations

N-Acetylcysteine Enhances Recovery From Acute Lung Injury in Man

1994 • 322 citations

Update on the Mechanisms of Immune Suppression of Injury and Immune Modulation

1996 • 297 citations

A fast and easy method to determine the production of reactive oxygen intermediates by human and murine phagocytes using dihydrorhodamine 123

1990 • 289 citations

Antioxidant status in patients with acute respiratory distress syndrome

1999 • 257 citations

Antioxidant treatment with N-acetylcysteine during adult respiratory distress syndrome

1992 • 247 citations

N-Acetylcysteine in experimental and clinical acute lung injury

1991 • 237 citations

N-acetyl-L-cysteine inhibits primary human T cell responses at the dendritic cell level: association with NF-kappaB inhibition.

1999 • 217 citations

Anti-CD18 antibody attenuates neutropenia and alveolar capillary-membrane injury during gram-negative sepsis.

1991 • 116 citations

Polymorphonuclear Leukocyte Activation

1993 • 113 citations

N-acetylcysteine inhibits human neutrophil and monocyte chemotaxis and oxidative metabolism

1988 • 101 citations

Oxidant-Antioxidant Balance in Granulocytes During ARDS

1996 • 85 citations

N-ACETYL CYSTEINE ATTENUATES ACUTE LUNG INJURY IN THE RAT

1995 • 85 citations

N-ACETYL CYSTEINE ATTENUATES ACUTE LUNG INJURY IN THE RAT

1997 • 76 citations

PENTOXIFYLLINE IMPROVES SURVIVAL AND REDUCES TUMOR NECROSIS FACTOR, INTERLEUKIN-6, AND ENDOTHELIN-1 IN FULMINANT INTRA-ABDOMINAL SEPSIS IN RATS

1995 • 70 citations

The association of impaired neutrophil chemotaxis with postoperative surgical sepsis

1986 • 68 citations

N-acetyl cysteine blocks mesangial VCAM-1 and NF-kappa B expression in vivo.

1997 • 62 citations

Effect of surgery on neutrophil functions, superoxide and leukotriene production

1988 • 56 citations

The role of N-acetylcystein administration on the oxidative response of neutrophils during cardiopulmonary bypass

1995 • 50 citations

Effects of oral N-acetylcysteine on cell content and macrophage function in bronchoalveolar lavage from healthy smokers

1988 • 49 citations

Flow cytometric parameters of neutrophil function as early indicators of sepsis- or trauma-related pulmonary or cardiovascular organ failure.

1990 • 48 citations

Increased translocation of bacteria from the gastrointestinal tracts of tumor-bearing mice

1985 • 45 citations

Neutrophil Function in Surgical Patients

1984 • 32 citations

Pentoxifylline improves bacterial clearance during hemorrhage and endotoxemia

1999 • 30 citations

Effects of N‐acetylcysteine on bacterial clearance

1996 • 28 citations

The effects of surgery on the activity of neutrophil granule proteins

1983 • 26 citations

Influence of N-acetylcysteine treatment on endotoxin-induced microcirculatory disturbances

1998 • 24 citations

N-acetylcysteine enhances receptor-mediated phagocytosis by human neutrophils.

1992 • 23 citations

Antioxidant status in patients with acute respiratory distress syndrome

1999 • 22 citations

Neutrophil function and glutathione-peroxidase (GSH-px) activity in healthy individuals after treatment with N-acetyl-L-cysteine

1997 • 17 citations

Modulation of inflammatory reactions by surgical trauma: Lack of relationship with corticosteroid secretion

1989 • 7 citations