Plasmid/liposome transfer of the human manganese superoxide dismutase transgene prevents ionizing irradiation-induced apoptosis in human esophagus organ explant culture

Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor

1989 • 821 citations

Multiinstitutional phase II trial of paclitaxel, carboplatin, and concurrent radiation therapy for locally advanced non-small-cell lung cancer.

1998 • 241 citations

Response, toxicity, failure patterns, and survival in five radiation therapy oncology group (RTOG) trials of sequential and/or concurrent chemotherapy and radiotherapy for locally advanced non–small-cell carcinoma of the lung

1998 • 225 citations

Phase I study to determine the maximum-tolerated dose of radiation in standard daily and hyperfractionated-accelerated twice-daily radiation schedules with concurrent chemotherapy for limited-stage small-cell lung cancer.

1998 • 195 citations

Prevention of late effects of irradiation lung damage by manganese superoxide dismutase gene therapy

1998 • 179 citations

Intratracheal injection of adenovirus containing the human MNSOD transgene protects athymic nude mice from irradiation-induced organizing alveolitis

1999 • 151 citations

Radioprotection of tumor and normal tissues by thiophosphate compounds

1973 • 136 citations

Radiation Pathology and the Clinical Response of Lung and Esophagus1

2015 • 131 citations

Manganese [correction of Magnesium] superoxide dismutase (MnSOD) plasmid/liposome pulmonary radioprotective gene therapy: Modulation of irradiation-induced mRNA for IL-I, TNF-alpha, and TGF-beta correlates with delay of organizing alveolitis/fibrosis

1999 • 116 citations

The influence of field size and other treatment factors on pulmonary toxicity following hyperfractionated irradiation for inoperable non-small cell lung cancer (NSCLC)-analysis of a radiation therapy oncology group (RTOG) protocol

1993 • 90 citations

Prevention of irradiation-induced esophagitis by plasmid/liposome delivery of the human manganese superoxide dismutase transgene

1999 • 78 citations

Protection against late effects of radiation by S-2-(3-aminopropylamino)-ethylphosphorothioic acid.

1991 • 51 citations

Overexpression of the human manganese superoxide dismutase (MnSOD) transgene in subclones of murine hematopoietic progenitor cell line 32D cl 3 decreases irradiation-induced apoptosis but does not alter G2/M or G1/S phase cell cycle arrest

1999 • 50 citations

Induction paclitaxel and carboplatin followed by concurrent chemoradiotherapy in patients with unresectable, locally advanced non-small cell lung carcinoma: report of Fox Chase Cancer Center study 94-001.

1997 • 48 citations

Protection against irradiation-induced damage to salivary glands by adrenergic agonist administration

1998 • 36 citations

The effect of dose rate and adriamycin on the tolerance of thoracic radiation in mice

1982 • 35 citations

Morphologic alterations in esophageal squamous cell carcinoma after preoperative high dose rate intraluminal brachytherapy

1996 • 30 citations

Isolation of cDNAs encoding human manganese superoxide dismutase

1988 • 24 citations

Results of multifield conformal radiation therapy of nonsmall-cell lung carcinoma using multileaf collimation beams

1999 • 21 citations

Prevention of irradiation-induced esophagitis by intraesophageal plasmid/liposome delivery of the human manganese superoxide dismutase (MNSOD) transgene

1998 • 17 citations

Development of multifield three‐dimensional conformal radiotherapy of lung cancer using a total lung dose/volume histogram

1995 • 15 citations

A phase I study of daily carboplatin and simultaneous accelerated, hyperfractionated chest irradiation in patients with regionally inoperable non-small cell lung cancer

1998 • 12 citations

48 Multi-institutional survival analysis of brain metastases patients treated with radiosurgery, stratified by RTOG RPA classification

1999 • 8 citations

2031 Human MnSOD transgene expression inhibits apoptosis induced by IL-3 withdrawal or TNF-α as well as ionizing irradiation in 32D CL 3 murine hematopoietic progenitor cells

1999 • 1 citations