Anticonvulsant actions of DS 103–282 Pharmacological studies in rodents and the baboon, Papio papio

A simplified method of evaluating dose-effect experiments.

1948 • 7,047 citations

Excitatory Amino Acid Transmitters

1981 • 2,488 citations

Anticonvulsant Action of Excitatory Amino Acid Antagonists

1982 • 692 citations

Protection against chemically induced seizures by 2-amino-7-phosphonoheptanoic acid

1982 • 258 citations

BACLOFEN: EFFECTS ON AMINO ACID RELEASE AND METABOLISM IN SLICES OF GUINEA PIG CEREBRAL CORTEX

1979 • 180 citations

Antiepileptic action of excitatory amino acid antagonists in the photosensitive baboon, papio papio

1983 • 179 citations

Anticonvulsant action of ethanolamine-O-sulphate and di-n-propylacetate and the metabolism of γ-aminobutyric acid (GABA) in mice with audiogenic seizures

1976 • 175 citations

Baclofen selectively inhibits transmission at synapses made by axons of CA3 pyramidal cells in the hippocampal slice.

1982 • 141 citations

Evaluation of anticonvulsant drugs in DBA/2 mice with sound-induced seizures.

1984 • 95 citations

Audiogenic seizures data in mice supporting new theories of biogenic amines mechanisms in the central nervous system

1967 • 90 citations

SELECTIVE DEPRESSION OF SYNAPTIC TRANSMISSION OF SPINAL NEURONES IN THE CAT BY A NEW CENTRALLY ACTING MUSCLE RELAXANT, 5‐CHLORO‐4‐(2‐IMIDAZOLIN‐2‐YL‐AMINO)‐2, 1, 3‐BENZOTHIODAZOLE (DS103–282)

1982 • 75 citations

The pharmacology of 5-chloro-4-(2-imidazolin-2-yl-amino)-2,1,3-benzothiadiazole (DS 103-282), a novel myotonolytic agent.

1980 • 75 citations

Behavioural and electrographic effects of L-5-hydroxytryptophan and D,L-parachlorophenyl-alanine on epileptic senegalese baboon (Papio papio)

1972 • 71 citations

Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity.

1980 • 56 citations

Noradrenergic influences on sound-induced seizures.

1980 • 56 citations

A double-blind comparative trial of new muscle relaxant, tizanidine (DS 103-282), and baclofen in the treatment of chronic spasticity in multiple sclerosis.

1981 • 50 citations

Convulsive effects of 4-deoxypyridoxine and of bicuculline in photosensitive baboons (Papio papio) and in rhesus monkeys (Macaca mulatta)

1971 • 47 citations

Photically induced epilepsy in Papio papio as a model for drug studies.

1975 • 36 citations

Effects of L-tryptophan, L-3, 4, dihydroxyphenylalanine and tranylcypromine on the electroencephalogram and on photically induced epilepsy in the baboon, Papio papio

1972 • 33 citations

Disorders of Neurohumoural Transmission

1983 • 31 citations