Gamma‐interferon causes a selective induction of the lysosomal proteases, cathepsins B and L, in macrophages

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Methods of Enzymatic Analysis

1975 • 20,446 citations

Methods of enzymatic analysis

1985 • 3,497 citations

[41] Cathepsin B, cathepsin H, and cathepsin L

1981 • 1,678 citations

MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

1994 • 1,448 citations

Antigen-Presenting Function of the Macrophage

1984 • 1,164 citations

Regulation of MHC Class II Expression by Interferon-γ Mediated by the Transactivator Gene CIITA

1994 • 854 citations

Proteolysis, proteasomes and antigen presentation

1992 • 576 citations

γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

1993 • 572 citations

Isolation and characterization of the intracellular MHC class II compartment

1994 • 426 citations

Selectivity of MHC-encoded peptide transporters from human, mouse and rat

1994 • 339 citations

Novel epoxysuccinyl peptides A selective inhibitor of cathepsin B, in vivo

1991 • 213 citations

Antigen processing for presentation by class II major histocompatibility complex requires cleavage by cathepsin E

1992 • 207 citations

Human liver cathepsin L

1985 • 191 citations

Peptide Translocation by Variants of the Transporter Associated with Antigen Processing

1993 • 188 citations

Identification of proteases that process distinct epitopes on the same protein.

1989 • 147 citations

Stefins and lysosomal cathepsins B, L and D in human breast carcinoma

1992 • 138 citations

Different roles for thiol and aspartyl proteases in antigen presentation of ovalbumin.

1990 • 113 citations

Participation of cathepsin B in processing of antigen presentation to MHC class II

1993 • 87 citations

Heterogeneity in antigen processing by different types of antigen-presenting cells. Effect of cell culture on antigen processing ability.

1992 • 85 citations

Selective inhibition of antigen presentation to cloned T cells by protease inhibitors

1989 • 84 citations

Acidification and disulfide reduction can be sufficient to allow intact proteins to bind class II MHC.

1993 • 79 citations

The generation of immunogenic peptides can be selectively increased or decreased by proteolytic enzyme inhibitors.

1991 • 75 citations

Purification of the complex of cathepsin L and the MHC class II‐associated invariant chain fragment from human kidney

1993 • 63 citations

Role of Proteasomes in Antigen Presentation

1993 • 61 citations

Selective inhibition of antigen presentation to cloned T cells by protease inhibitors.

1988 • 61 citations

Molecular cloning of two new interferon-induced, highly related nuclear phosphoproteins.

1993 • 52 citations

Diminished antigen processing by endosomal acidification mutant antigen-presenting cells.

1989 • 50 citations

Cathepsin B in tumors, normal tissue and isolated cells from the human lung.

1994 • 31 citations

Immunological significances of invariant chain from the aspect of its structural homology with the cystatin family

1994 • 23 citations

Effect of interferon‐γ on antigen processing in human monocytes

1994 • 22 citations

Cellular events accompanying regression of skin recurrences of breast carcinomas treated with intralesional injections of natural interferons alpha and gamma.

1992 • 17 citations

Evidence supporting a role for cathepsin B in the generation of T cell antigenic epitopes of human growth hormone

1993 • 12 citations

Major involvement of cathepsin B in the intracellular proteolytic processing of exogenous IgGs in U937 cells

1993 • 10 citations