The kinetics of protein-protein recognition

Funnels, pathways, and the energy landscape of protein folding: A synthesis

1995 • 2,607 citations

Facilitated Target Location in Biological Systems

1989 • 1,011 citations

Entropic Contributions to Rate Accelerations in Enzymic and Intramolecular Reactions and the Chelate Effect

1971 • 980 citations

The structure of protein-protein recognition sites.

1990 • 825 citations

Diffusion-Controlled Macromolecular Interactions

1985 • 699 citations

Evidence for a molten globule state as a general intermediate in protein folding

1990 • 677 citations

Kinetics of protein-protein association explained by Brownian dynamics computer simulation.

1992 • 578 citations

Rapid, electrostatically assisted association of proteins

1996 • 562 citations

Energetics of protein-protein interactions: Analysis ofthe Barnase-Barstar interface by single mutations and double mutant cycles

1995 • 559 citations

Faster superoxide dismutase mutants designed by enhancing electrostatic guidance

1992 • 387 citations

On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.3, and HyHEL-5

1989 • 367 citations

Protein-protein recognition: Crystal structural analysis of a barnase-barstar complex at 2.0-.ANG. resolution

1994 • 359 citations

The price of lost freedom: entropy of bimolecular complex formation

1989 • 323 citations

The Contribution of Vibrational Entropy to Molecular Association

1994 • 312 citations

Interaction of barnase with its polypeptide inhibitor barstar studied by protein engineering

1993 • 283 citations

Trypsin-pancreatic trypsin inhibitor association. Dynamics of the interaction and role of disulfide bridges

1972 • 251 citations

Absolute and relative binding free energy calculations of the interaction of biotin and its analogs with streptavidin using molecular dynamics/free energy perturbation approaches

1993 • 227 citations

Barnase and barstar: two small proteins to fold and fit together

1989 • 222 citations

Molecular structure of a new family of ribonucleases

1982 • 222 citations

Entropy in biological binding processes: Estimation of translational entropy loss

1994 • 179 citations

Protein-protein recognition

1995 • 178 citations

Co-operativity in protein-protein association

1989 • 162 citations

Protein‐protein recognition analyzed by docking simulation

1991 • 147 citations

Principles of protein-protein recognition from structure to thermodynamics

1995 • 147 citations

Brownian dynamics study of the influences of electrostatic interaction and diffusion on protein-protein association kinetics

1993 • 146 citations

Elusive affinities

1995 • 145 citations

The Contribution of Contact and Non-contact Residues of Antibody in the Affinity of Binding to Antigen

1993 • 128 citations

Point charge distributions and electrostatic steering in enzyme/substrate encounter: Brownian dynamics of modified copper/zinc superoxide dismutases

1990 • 123 citations

Alanine Point-Mutations in the Reactive Region of Bovine Pancreatic Trypsin Inhibitor: Effects on the Kinetics and Thermodynamics of Binding to β-Trypsin and α-Chymotrypsin

1996 • 119 citations

Recognition between a bacterial ribonuclease, barnase, and its natural inhibitor, barstar

1993 • 106 citations

Three-dimensional solution structure and 13C assignments of barstar using nuclear magnetic resonance spectroscopy

1994 • 100 citations

Molecular dynamics studied by analysis of the X-ray diffuse scattering from lysozyme crystals

1987 • 92 citations

Protein-protein interaction: a genetic selection for compensating mutations at the barnase-barstar interface.

1996 • 46 citations

Diffusion-controlled association rate of cytochrome c and cytochrome c peroxidase in a simple electrostatic model

1986 • 46 citations

Reaction pathway for the quaternary structure change in hemoglobin

1985 • 41 citations