Established IL‐2‐dependent double‐negative (CD4^‐ CD8^‐) TCRαβ/CD3⁺ ATL cells: induction of CD4 expression

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma

1980 • 5,022 citations

Adult T-cell leukemia: antigen in an ATL cell line and detection of antibodies to the antigen in human sera.

1981 • 2,281 citations

Adult T-cell leukemia: clinical and hematologic features of 16 cases

1977 • 2,119 citations

Adult T-cell leukemia: clinical and hematologic features of 16 cases

1977 • 1,750 citations

Monoclonal integration of human T-cell leukemia provirus in all primary tumors of adult T-cell leukemia suggests causative role of human T-cell leukemia virus in the disease.

1984 • 886 citations

Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction.

1990 • 526 citations

T Cell Antigen Receptor-Mediated Activation of Phospholipase C Requires Tyrosine Phosphorylation

1990 • 476 citations

Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulation.

1990 • 432 citations

T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis.

1989 • 402 citations

Coexpression of T4 and T8 on peripheral blood T cells demonstrated by two-color fluorescence flow cytometry.

1985 • 261 citations

Induction of CD4 and susceptibility to HIV-1 infection in human CD8+ T lymphocytes by human herpesvirus 6

1991 • 259 citations

Liver is a possible site for the proliferation of abnormal CD3+4-8- double-negative lymphocytes in autoimmune MRL-lpr/lpr mice.

1990 • 173 citations

Rapid phosphorylation and modulation of the T4 antigen on cloned helper T cells induced by phorbol myristate acetate or antigen.

1986 • 171 citations

Phenotypic and functional analysis of leukemic cells from 16 patients with adult T-cell leukemia/lymphoma

1983 • 166 citations

Interleukin-4 mediates CDS induction on human CD4+ T-cell clones

1988 • 163 citations

Isolation of HTLV-transformed B-lymphocyte clone from a patient with HTLV-associated adult T-cell leukaemia

1984 • 107 citations

T4 endocytosis and phosphorylation induced by phorbol esters but not by mitogen or HIV infection.

1988 • 81 citations

A rapid method for separating functionally intact human T lymphocytes with monoclonal antibodies

1981 • 77 citations

Internalization of human T lymphocyte receptors

1987 • 73 citations

Double-negative (CD4-CD8-) lymphocytes bearing T-cell receptor alpha and beta chains in normal human skin.

1989 • 70 citations

Co-expression of CD4 and CD8 molecules and de novo expression of MHC class II antigens on activated rat T cells.

1986 • 68 citations

Demethylated CD8 Gene in CD4⁺T Cells Suggests that CD4⁺Cells Develop from CD8⁺Precursors

1988 • 68 citations

Tumor-promoting phorbol esters selectively abrogate the expression of the T4 differentiation antigen expressed on normal and malignant (Sézary) T helper lymphocytes.

1982 • 66 citations

Differentiation of human T-lymphoid leukemia cells into cells that have a suppressor phenotype is induced by phorbol 12-myristate 13-acetate.

1982 • 56 citations

Definition of a population of CD4-8- T cells that express the alpha beta T-cell receptor and respond to interleukins 2, 3, and 4.

1989 • 47 citations

Effect of an inhibitor of DNA methylation on T cells. I. 5-Azacytidine induces T4 expression on T8+ T cells.

1986 • 46 citations

Adult T cell leukemia with atypical surface phenotypes: clinical correlation.

1985 • 45 citations

IL-2-Dependent ATL cell lines with phenotypes differing from the original leukemia cells

1991 • 35 citations

Changes of adult T cell leukemia cell surface antigens at relapse or at exacerbation phase after chemotherapy defined by use of monoclonal antibodies

1984 • 33 citations

Adult T-cell leukemia with an unusual phenotype, Leu-2a positive and Leu-3a negative

1985 • 26 citations

Adult T cell leukaemia cells are of CD4⁺ CDw29⁺ T cell origin and secrete a B cell differentiation factor

1989 • 23 citations

Model for studying virus attachment. II. Binding of biotinylated human T cell leukemia virus type I to human blood mononuclear cells potential targets for human T cell leukemia virus type I infection.

1991 • 20 citations

A subset of OKT4⁺ peripheral T cells can generate colonies containing mixed progeny with OKT4⁺ helper and OKT8⁺ suppressor cells

1985 • 19 citations

A novel CD45RA⁺CD4⁺ transient thymic subpopulation in MRL-lpr/lpr mice: its relation to non-proliferating CD4⁻CD8⁻CD45RA⁺ tumor cells

1993 • 8 citations

DISAPPEARANCE OF CD4 ANTIGEN IN A CASE OF ADULT T CELL LEUKAEMIA

1992 • 3 citations