Nicotinic-agonist stimulated 86Rb+ efflux and [3H]epibatidine binding of mice differing in β2 genotype

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

1993 • 1,455 citations

Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine

1998 • 1,304 citations

Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat

1989 • 1,049 citations

Physiological Diversity of Nicotinic Acetylcholine Receptors Expressed by Vertebrate Neurons

1995 • 1,017 citations

Hippocampal synaptic transmission enhanced by low concentrations of nicotine

1996 • 955 citations

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

1990 • 923 citations

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment.

1992 • 858 citations

Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats

1986 • 693 citations

Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain

1995 • 659 citations

Horizontal integration and cortical dynamics

1992 • 589 citations

Both alpha- and beta-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors

1991 • 552 citations

Reduced antinociception in mice lacking neuronal nicotinic receptor subunits

1999 • 546 citations

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes.

1993 • 543 citations

Nicotine binding and nicotinic receptor subunit RNA after chronic nicotine treatment

1992 • 540 citations

Systemic nicotine‐induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area

1994 • 524 citations

Mice Deficient in the α7 Neuronal Nicotinic Acetylcholine Receptor Lack α-Bungarotoxin Binding Sites and Hippocampal Fast Nicotinic Currents

1997 • 493 citations

Brain α-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily

1990 • 471 citations

Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor

1991 • 463 citations

Functional contributions of α5 subunit to neuronal acetylcholine receptor channels

1996 • 389 citations

Identification of four classes of brain nicotinic receptors using beta2 mutant mice.

1998 • 388 citations

Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors h alpha 2 beta 2, h alpha 2 beta 4, h alpha 3 beta 2, h alpha 3 beta 4, h alpha 4 beta 2, h alpha 4 beta 4 and h alpha 7 expressed in Xenopus oocytes.

1997 • 387 citations

Assembly of Human Neuronal Nicotinic Receptor α5 Subunits with α3, β2, and β4 Subunits

1996 • 338 citations

Neuronal nicotinic acetylcholine receptor activation modulates gamma-aminobutyric acid release from CA1 neurons of rat hippocampal slices.

1997 • 330 citations

Identification of Four Classes of Brain Nicotinic Receptors Using β2 Mutant Mice

1998 • 323 citations

Influence of Subunit Composition on Desensitization of Neuronal Acetylcholine Receptors at Low Concentrations of Nicotine

1997 • 320 citations

Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure

1991 • 313 citations

Primary structure and expression of β2: A novel subunit of neuronal nicotinic acetylcholine receptors

1988 • 301 citations

The functional diversity of the neuronal nicotinic acetylcholine receptors is increased by a novel subunit: β4

1989 • 294 citations

Megacystis, mydriasis, and ion channel defect in mice lacking the α3 neuronal nicotinic acetylcholine receptor

1999 • 286 citations

Multiorgan Autonomic Dysfunction in Mice Lacking the β2 and the β4 Subunits of Neuronal Nicotinic Acetylcholine Receptors

1999 • 281 citations

Characterization of bovine and human neuronal nicotinic acetylcholine receptors using monoclonal antibodies

1988 • 241 citations

Immunocytochemical localization of a neuronal nicotinic receptor: the beta 2-subunit

1993 • 222 citations

Role of Ca²⁺Ions in Nicotinic Facilitation of GABA Release in Mouse Thalamus

1997 • 221 citations

The α5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain

1992 • 205 citations

Characterization of (+/-)(-)[3H]epibatidine binding to nicotinic cholinergic receptors in rat and human brain.

1995 • 194 citations

Existence of different subtypes of nicotinic acetylcholine receptors in the rat habenulo-interpeduncular system

1991 • 193 citations

Desensitization of the nicotine‐induced mesolimbic dopamine responses during constant infusion with nicotine

1995 • 168 citations

Genetic influences on nicotine responses

1989 • 167 citations

Neuronal nicotinic receptor beta2 and beta4 subunits confer large differences in agonist binding affinity.

1998 • 166 citations

Neuronal Nicotinic Receptor β2 and β4 Subunits Confer Large Differences in Agonist Binding Affinity

1998 • 153 citations

Differential agonist inhibition identifies multiple epibatidine binding sites in mouse brain.

1998 • 145 citations

Pharmacological characterization of nicotinic receptor-stimulated GABA release from mouse brain synaptosomes.

1998 • 131 citations

Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the beta2 subunit.

1999 • 129 citations

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. II. The rundown and inward rectification of agonist-elicited whole-cell currents and identification of receptor subunits by in situ hybridization.

1994 • 109 citations

Variation of nicotinic binding sites among inbred strains

1989 • 99 citations

A Reporter Mutation Approach Shows Incorporation of the “Orphan” Subunit β3 into a Functional Nicotinic Receptor

1998 • 99 citations

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. III. Agonist actions of the novel alkaloid epibatidine and analysis of type II current.

1995 • 82 citations

? subunits determine the time course of desensitization in rat ?3 neuronal nicotinic acetylcholine receptors

1991 • 59 citations

Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes: role of the ? subunit in agonist sensitivity and desensitization

1991 • 56 citations

Differential desensitization properties of rat neuronal nicotinic acetylcholine receptor subunit combinations expressed inXenopus laevis oocytes

1995 • 49 citations

Sodium channel blockers partially inhibit nicotine-stimulated 86Rb+ efflux from mouse brain synaptosomes.

1995 • 31 citations