Effects of Cryopreservation on Immune Responses

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

1991 • 3,812 citations

The Pathophysiology of Tumor Necrosis Factors

1992 • 1,880 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

1986 • 1,501 citations

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

1989 • 1,183 citations

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.

1996 • 1,167 citations

ASSOCIATION BETWEEN TUMOUR NECROSIS FACTOR IN SERUM AND FATAL OUTCOME IN PATIENTS WITH MENINGOCOCCAL DISEASE

1987 • 1,108 citations

Critical protective role of mast cells in a model of acute septic peritonitis

1996 • 942 citations

Stimulation of neutrophils by tumor necrosis factor.

1986 • 847 citations

Tumour necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, γ-interferon and interleukin-1

1986 • 781 citations

Antiviral effects of recombinant tumour necrosis factor in vitro

1986 • 392 citations

Predominant role of tumor necrosis factor-alpha in human monocyte IL-10 synthesis.

1993 • 386 citations

Tumor necrosis factor: a potent effector molecule for tumor cell killing by activated macrophages.

1986 • 360 citations

The antitumor function of tumor necrosis factor (TNF), I. Therapeutic action of TNF against an established murine sarcoma is indirect, immunologically dependent, and limited by severe toxicity.

1988 • 276 citations

Tumor necrosis factor-alpha enhances cytolytic activity of human natural killer cells.

1987 • 235 citations

Enhancement of antigen- and mitogen-induced human T lymphocyte proliferation by tumor necrosis factor-alpha.

1988 • 221 citations

Regulation of interleukin 10 release by tumor necrosis factor in humans and chimpanzees.

1994 • 189 citations

Inhibition of IL-10 expression by IFN-gamma up-regulates transcription of TNF-alpha in human monocytes.

1995 • 174 citations

Differences in the synthesis and kinetics of release of interleukin 1α, interleukin 1β and tumor necrosis factor from human mononuclear cells

1989 • 163 citations

Effect of cell concentration on bone marrow and peripheral blood stem cell cryopreservation

1994 • 139 citations

Peripheral blood-derived stem cell collections for use in autologous transplantation after high dose chemotherapy: an alternative approach.

1990 • 84 citations

Phenotype and frequency of cells secreting IL-2, IL-4, IL-6, IL-10, IFN and TNF-α in human peripheral blood

1995 • 78 citations

Tumor necrosis factor alpha is a potent synergistic factor for the proliferation of primitive human hematopoietic progenitor cells and induces resistance to transforming growth factor beta but not to interferon gamma.

1996 • 57 citations

TNF-alpha bidirectionally modulates the viability of primitive murine hematopoietic progenitor cells in vitro.

1996 • 30 citations

Susceptibility of human T cells, T-cell subsets, and B cells to cryopreservation

1986 • 19 citations

Effects of Cryopreservation on Immune Responses: VII. Freezing Induced Enhancement of IL-6 Production in Human Peripheral Blood Mononuclear Cells

1994 • 18 citations

Cryopreservation enhances interleukin-1 production in human mononuclear cells

1990 • 12 citations

Effects of Cryopreservation on Immune Responses

1996 • 10 citations

Effects of Cryopreservation on Immune Responses: IX. Stimulus-Mediated Dichotomy in IL-10 Production by Frozen Human Peripheral Blood Mononuclear Cells

1996 • 9 citations