Substance P and somatostatin coexist within neuritic plaques: Implications for the pathogenesis of Alzheimer's disease

Cholinergic innervation of cortex by the basal forebrain: Cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (Substantia innominata), and hypothalamus in the rhesus monkey

1983 • 1,898 citations

APRIORITY

1961 • 1,293 citations

NEUROTRANSMITTER-RELATED ENZYMES AND INDICES OF HYPOXIA IN SENILE DEMENTIA AND OTHER ABIOTROPHIES

1976 • 1,272 citations

Trophic Interactions Between Astroglial Cells and Hippocampal Neurons in Culture

1980 • 672 citations

ULTRASTRUCTURAL STUDIES IN ALZHEIMER'S PRESENILE DEMENTIA.

1964 • 646 citations

Detection of substance P in the central nervous system by a monoclonal antibody.

1979 • 594 citations

Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer's disease: a quantitative study of visual and auditory cortices

1987 • 569 citations

The immunocytochemical localization of somatostatin-containing neurons in the rat central nervous system

1981 • 487 citations

Plasticity of Hippocampal Circuitry in Alzheimer's Disease

1985 • 457 citations

Reduced amounts of immunoreactive somatostatin in the temporal cortex in senile dementia of Alzheimer type

1980 • 434 citations

Quantitative morphology and regional and laminar distributions of senile plaques in Alzheimer's disease

1985 • 414 citations

Adult rat brain astrocytes support survival of both NGF-dependent and NGF-insensitive neurones

1979 • 378 citations

Persistence of cholinergic neurons in the basal nucleus in a brain with senile dementia of the Alzheimer's type demonstrated by immunohistochemical staining for choline acetyltransferase

1983 • 332 citations

Substance P in the ascending cholinergic reticular system

1983 • 294 citations

Synthesis and secretion of nerve growth factor by mouse astroglial cells in culture

1986 • 278 citations

Cortical somatostatin-like immunoreactivity in cases of Alzheimer's disease and senile Dementia of the Alzheimer type

1981 • 274 citations

Reduced dopamine-beta-hydroxylase activity in Alzheimer's disease

1981 • 266 citations

Somatostatin immunoreactivity in neuritic plaques of Alzheimer's patients

1985 • 263 citations

Cholinergic Innervation in Neuritic Plaques

1982 • 249 citations

Astrocytes are important for sprouting in the septohippocampal circuit

1988 • 230 citations

Neuropeptides in Alzheimer type dementia

1983 • 214 citations

Biological Aspects of Alzheimer's Disease

1984 • 203 citations

Retrograde changes in cholinergic neurons in the basal forebrain of the rat following cortical damage

1983 • 197 citations

Neuritic plaques in senile dementia of Alzheimer type: a Golgi analysis in the hippocampal region

1983 • 194 citations

Dendritic sprouting in Alzheimer's presenile dementia

1978 • 174 citations

Neuropathological and biochemical observations on the noradrenergic system in Alzheimer's disease

1981 • 171 citations

An immunohistochemical characterization of somatostatin‐28 and somatostatin‐28_1–12 in monkey prefrontal cortex

1986 • 163 citations

Fibrous Astrocytes in Senile Dementia of the Alzheimer Type

1981 • 159 citations

II. Cortical neurons immunoreactive with antisera against neuropeptide Y are altered in Alzheimer's‐type dementia

1985 • 146 citations

Cortical Substance P‐Like Immunoreactivity in Cases of Alzheimer's Disease and Senile Dementia of the Alzheimer Type

1982 • 141 citations

Evidence for Cholinergic Neurites in Senile Plaques

1984 • 140 citations

Light microscopic and ultrastructural localization of immunoreactive substance P in the dorsal horn of monkey spinal cord

1982 • 128 citations

Retrograde cell degeneration in the basal nucleus in monkey and man

1983 • 125 citations

Distribution of altered hippocampal neurons and axons immunoreactive with antisera against neuropeptide Y in Alzheimer's‐type dementia

1986 • 106 citations

HISTOCHEMICAL OBSERVATIONS ON CHOLINESTERASE ACTIVITIES IN THE BRAINS OF ELDERLY NORMAL AND DEMENTED (ALZHEIMER-TYPE) PATIENTS

1980 • 103 citations

Somatostatin-like immunoreactivity within neuritic plaques

1985 • 86 citations

Neuropeptidergic Systems in Plaques of Alzheimerʼs Disease

1987 • 84 citations

Somatostatin: Localization and distribution in the cortex and the subcortical white matter of human brain

1982 • 82 citations

Catecholaminergic neurites in senile plaques in prefrontal cortex of aged nonhuman primates

1985 • 81 citations

Somatostatin- and Neuropeptide Y-immunoreactive neurons in the neocortex in senile dementia of alzheimer's type

1986 • 78 citations

Multiple Transmitter Systems Contribute Neurites to Individual Senile Plaques

1988 • 67 citations

Glutamic acid decarboxylase-like immunoreactive neurites in senile plaques

1985 • 65 citations

Evidence for the existence of a substance P-containing pathway from the nucleus laterodorsalis tegmenti (Castaldi) to the medial frontal cortex of the rat

1983 • 63 citations

Choline acetyltransferase immunoreactivity in neuritic plaques of Alzheimer brain

1986 • 58 citations

Neuropeptide Y-like immunoreactivity in neuritic plaques of Alzheimer's disease

1985 • 58 citations

Somatostatinergic neurites in senile plaques of aged non-human primates

1984 • 57 citations

Innervation of human hippocampus by noradrenergic systems: Normal anatomy and structural abnormalities in aging and in Alzheimer's disease

1988 • 50 citations

Acetylcholinesterase fibers and the development of senile plaques

1987 • 50 citations

Neuropeptides and neuropathology in the amygdala in Alzheimer's disease: relationship between somatostatin, neuropeptide Y and subregional distribution of neuritic plaques

1988 • 48 citations

Acetylcholinesterase activity in senile plaques of aged macaques

1984 • 45 citations

Substance P immunoreactivity within neuritic plaques

1985 • 42 citations

Neocortical substance P neurons in the baboon: An immunohistochemical finding

1983 • 29 citations

Morphologic alterations of chohnergic processes in the neocortex of aged rats

1988 • 29 citations

Alzheimer dementia and reduced nicotinamide adenine dinucleotide (NADH)-diaphorase activity in senile plaques and the basal forebrain

1985 • 28 citations

Cell-free biosynthesis of multiple preprosomatostatins: characterization by hybrid selection and amino-terminal sequencing

1984 • 18 citations