Current Views on Formation of Thyroid Hormones

The Thyroid and Its Diseases

1964 • 710 citations

The Oxidation of Tyramine, Tyrosine, and Related Compounds by Peroxidase

1959 • 363 citations

THE TEMPORARY NATURE OF THE INHIBITORY ACTION OF EXCESS IODIDE ON ORGANIC IODINE SYNTHESIS IN THE NORMAL THYROID¹

1949 • 281 citations

Extrathyroidal Iodide Concentrating Mechanisms

1961 • 228 citations

The Properties of Thyroglobulin

1962 • 191 citations

Elaboration of Thyroglobulin in the Thyroid Follicle

1964 • 189 citations

CHANGES IN THYROIDAL FUNCTION DURING ADAPTATION TO LARGE DOSES OF IODIDE*

1963 • 181 citations

Iodide Peroxidase in Rat Thyroid and Salivary Glands and Its Inhibition by Antithyroid Compounds

1959 • 162 citations

Endemic Goiter

1954 • 142 citations

Advances in Thyroid Research

1962 • 134 citations

Peroxidase Activity in Thyroid Gland and Partial Purification of the Enzyme

1962 • 116 citations

Stimulation in Vitro of Pathways of Glucose Oxidation in Thyroid by Thyroid-stimulating Hormone

1960 • 109 citations

THE EFFECTS OF IODIDE, PERCHLORATE, THIOCYANATE,AND NITRATE ADMINISTRATION UPON THEIODIDE CONCENTRATING MECHANISMOF THE RAT THYROID*

1953 • 107 citations

The iodination of tyrosine by beef thyroid preparations

1962 • 95 citations

Iodine metabolism of dispersed thyroid cells obtained by trypsinization of sheep thyroid glands

1962 • 85 citations

LOCALIZATION OF PROTEIN-BOUND I¹³¹IN THE THYROID GLAND OF THE MOUSE

1955 • 85 citations

CONGENITAL HYPOTHYROIDISM WITH GOITRE ABSENCE OF AN IODIDE-CONCENTRATING MECHANISM

1960 • 85 citations

Studies on the Biosynthesis of Iodotyrosines: A Soluble Thyroidal Iodide-Peroxidase Tyrosine-Iodinase System

1962 • 85 citations

Active transport of iodide by choroid plexus of the rabbit in vitro

1962 • 85 citations

BIOSYNTHESIS OF THYROGLOBULIN: RELATIONSHIP TO RNA-TEMPLATE AND PRECURSOR PROTEIN

1963 • 81 citations

The Oxidation of 3,5-Diiodotyrosine to Thyroxine

1942 • 80 citations

Thyroidal Iodide Transport

1963 • 77 citations

CONVERSION OF INORGANIC I131 TO ORGANIC I131 BY CELL-FREE PREPARATIONS OF THYROID TISSUE

1955 • 76 citations

TYROSINE IODINASE

1954 • 74 citations

The oxidation of diiodotyrosine derivatives

1948 • 70 citations

THE FORMATION IN VITRO OF THYROXINE AND DIIODOTYROSINE BY THYROID TISSUE WITH RADIOACTIVE IODINE AS INDICATOR

1943 • 68 citations

The Requirement Of Monoiodotyrosine Deiodinase For Triphosphopyridine Nucleotide

1957 • 67 citations

Thyroglobulin Fractionation on Diethylaminoethyl Cellulose Columns

1963 • 66 citations

FACTORS GOVERNING THE DEVELOPMENT OF THE CHICK EMBRYO THYROID. II. CHRONOLOGY OF THE SYNTHESIS OF IODINATED COMPOUNDS STUDIED BY CHROMATOGRAPHIC ANALYSIS*†

1955 • 66 citations

The syndrome of congenital goiter with butanol-insoluble serum iodine

1959 • 63 citations

Enzyme Systems Concerned with the Synthesis of Monoiodotyrosine

1958 • 63 citations

The chemical conversion of di-iodotyrosine into thyroxine

1945 • 63 citations

THE IODIDE TRAPPING AND BINDING FUNCTIONS OF THE THYROID

1955 • 62 citations

Iodide Binding in Thyroid Cellular Fractions

1960 • 62 citations

Hashimoto's thyroiditis. A genetically conditioned disease.

1962 • 58 citations

STUDIES ON AN IODINATED PROTEIN IN THE SERUM OF SUBJECTS WITH CANCER OF THE THYROID*†

1956 • 57 citations

Correlation of micro‐electrode potential recordings with histology of rat and guinea‐pig thyroid glands

1963 • 55 citations

METABOLISM OF I131 BY THE MARINE ALGA, NEREOCYSTIS LUETKEANA

1955 • 54 citations

Behavior of the Thyroid Toward Elements of the Seventh Periodic Group

1956 • 53 citations

Evaluation of the Homogeneity of Several Thyroglobulin Preparations

1961 • 53 citations

Intermediary metabolism of thyroid tissue and the action of drugs.

1963 • 52 citations

THE SYNTHESIS OF ORGANICALLY BOUND IODINE BY CELL-FREE PREPARATIONS OF THYROID TISSUE

1953 • 51 citations

Thyroidal Iodine Heterogeneity: “Last Come, First Served” System of Iodine Turnover

1964 • 51 citations

THE ROLE OF INTERMEDIARY CARBOHYDRATE METABOLISM IN REGULATING ORGANIC IODINATIONS IN THE THYROID GLAND*

1961 • 51 citations

UTILIZATION OF RADIOACTIVE IODIDE BY CELL-FREE PREPARATIONS OF BEEF THYROID TISSUE

1953 • 50 citations

PLASMA INORGANIC IODIDE, A CHEMICAL REGULATOR OF NORMAL THYROID FUNCTION¹

1948 • 49 citations

The Reversible Dissociation of Thyroid Iodide Peroxidase into Apoenzyme and Prosthetic Group

1962 • 49 citations

Transport of radioiodide between thyroid gland and blood in mice and rats

1958 • 47 citations

Iodide transport by the rabbit eye

1961 • 45 citations

THYROID I¹³¹METABOLISM IN THE ABSENCE OF THE PITUITARY: THE UNTREATED, HYPOPHYSECTOMIZED RAT1¹

1958 • 44 citations

OBSERVATIONS ON A RELATIONSHIP BETWEEN TOTAL THYROID IODINE CONTENT AND THE IODIDE-CONCENTRATING MECHANISM OF THE THYROID GLAND OF THE RAT¹

1954 • 42 citations

Studies on the mechanism of iodination by the thyroid gland: Iodide-activating enzyme and an intracellular inhibitor of iodination

1961 • 42 citations

Reaction of 4-Hydroxy-3,5-diiodophenylpyruvic Acid with 3,5-Diiodotyrosine

1961 • 42 citations

EFFECT OF METABOLIC INHIBITORS UPON IODIDE TRANSPORT IN SHEEP THYROID SLICES*†

1955 • 42 citations

Effect of Monofluorosulphonate, Difluorophosphate and Fluoroborate Ions on the Iodine Uptake of the Thyroid Gland

1959 • 41 citations

Thyrotropin-stimulated adenosine triphosphate in isolated thyroid cell membranes

1962 • 40 citations

The Iodinated Albuminlike Component of the Plasma of Thyrotoxic Patients

1962 • 40 citations

10D0PR0TEINS IN NORMAL AND ABNORMAL HUMAN THYROID TISSUE AND IN NORMAL SHEEP THYROID¹

1959 • 40 citations

FURTHER OBSERVATIONS CONCERNING THE ACTION OF PITUITARY THYROTROPIN ON THE INTERMEDIATE METABOLISM OF SHEEP THYROID TISSUEin vitro¹²

1960 • 40 citations

Congenital Goitrous Cretinism Due to the Absence of Iodide-Concentrating Ability

1964 • 39 citations

Studies on the Biosynthesis of Iodotyrosines

1961 • 39 citations

Pyridine Nucleotides in the Thyroid

1963 • 39 citations

STUDIES ON PROTEINS OF NORMAL AND DISEASED THYROID GLANDS*†

1960 • 35 citations

CERTAIN FUNCTIONS OF ISOLATED THYROID CELLS

1961 • 35 citations

An iodide-complexing phospholipid

1962 • 35 citations

Stimulation in vitro of hexose monophosphate pathway in thyroid by iodotyrosines and synkavit

1961 • 34 citations

Recent progress in the physiology and biochemistry of thyroid hormones

1956 • 34 citations

AN UNIDENTIFIED IODINE COMPOUND FORMED BY INCUBATION OF CELL-FREE PREPARATIONS OF TISSUE WITH IODIDE-I131

1957 • 34 citations

ACTIVATION OF THE IODINATING SYSTEM IN SHEEP THYROID PARTICULATE FRACTIONS BY FLAVIN COFACTORS

1957 • 34 citations

EFFECT OF THYROTROPIN ON THE RELEASE OF IODIDE FROM THE THYROID

1960 • 33 citations

Hexose monophosphate pathway in thyroid tissue

1960 • 33 citations

Proteolysis of Thyroglobulin by Thyroid Enzymes

1961 • 31 citations

RELATION OF NUCLEIC ACIDS TO THE STRUCTURE AND FUNCTION OF THE GUINEA PIG THYROID GLAND

1959 • 31 citations

Thyroid Function in Rats and Chickens. Equilibration of Injected Iodide with Existing Thyroidal Iodine in Long-Evans Rats and White Leghorn Chickens1

1964 • 30 citations

THE METABOLISM OF I¹³¹BY SURVIVING SLICES OF RAT MAMMARY TISSUE1

1956 • 29 citations

Pathways of thyroid phosphorus metabolism. The phospholipids of sheep thyroid

1958 • 29 citations

REGULATION OF THE RAT THYROID IN SHORTTERM IODINE DEFICIENCY¹

1954 • 29 citations

Studies on the Biosynthesis of Iodotyrosines: The Relationship of Peroxidase, Catalase and Cytochrome Oxidase

1962 • 29 citations

Preliminary Communication

1953 • 29 citations

The Effect of Propylthiouracil on the Intrathyroid Metabolism of Iodine in Rats

1960 • 28 citations

THYROID I¹³¹METABOLISM IN THE ABSENCE OF THE PITUITARY: THE HYPOPHYSECTOMIZED RAT TREATED WITH THYROTROPIC HORMONE¹

1958 • 28 citations

CARBOHYDRATE METABOLISM IN THE THYROID GLAND*†

1960 • 27 citations

Thyroid Function in a Goiter Endemic: I. Impairment of Hormone Synthesis and Secretion in the Goitrous Gland

1963 • 27 citations

Thyroid Function in a Goitrous Endemic: II. Nonhormonal Iodine Escape from the Goitrous Gland

1963 • 26 citations

THE MECHANISM OF IODINATION REACTIONS IN THYROID GLANDS¹

1961 • 26 citations

Appearance of Serine upon Alkaline Incubation of Iodinated Polytyrosine

1956 • 26 citations

Stimulation of Purine Synthesis in Vitro in the Calf Thyroid by Thyroid-stimulating Hormone

1963 • 26 citations

Iodine metabolism in the thyroid gland of the rat

1962 • 26 citations

COMPARISON OF THYROIDAL AND GASTRIC IODIDE PUMPS IN RATS¹

1959 • 25 citations

Stimulation of Alpha Aminoisobutyric Acid-C¹⁴by Thyrotropin Uptake in Thyroid Slices

1962 • 25 citations

ENDEMIC GOITER IN THE UELE REGION. 11.SYNTHESIS AND SECRETION OF THYROID HORMONES*

1961 • 24 citations

IODOTYROSYL COUPLING DEFECT IN CONGENITAL HYPOTHYROIDISM WITH GOITRE

1963 • 24 citations

EFFECT OF THYROTROPHIN ON THE METABOLISM OF IODIDE¹³¹IN THE THYROID GLAND

1961 • 24 citations

SIMULTANEOUS MEASUREMENT OF THE IODIDECONCENTRATING AND PROTEIN-BINDING CAPACITIES OF THE NORMAL AND HYPERFUNCTIONING HUMAN THYROID GLAND*

1955 • 24 citations

Eumetabolic Goitrous Adult with Iodopre albumin in Thyroid Tissue and Blood

1964 • 23 citations

IODOPROTEINS IN THE THYROID

1960 • 23 citations

Cardiac Glycosides and Thyroidal Iodide Transport

1958 • 23 citations

CONCENTRATION GRADIENTS FOR RADIOIODIDE IN UNBLOCKED THYROID GLANDS OF RATS: EFFECTOF PERCHLORATE1

1956 • 23 citations

The free iodotyrosines of the rat thyroid gland

1963 • 23 citations

Localization of protein-bound radioactive iodine in rat thyroid glands labelled with 125I or 131I

1964 • 22 citations

Thyroidal Iodoproteins in Patients with Goitrous Hypothyroidism

1964 • 21 citations

Demonstration of a Second Thyroidal Iodide Pool in Rat Thyroid Glands by Double Isotope Labeling1

1963 • 21 citations

Heterogeneity of rat thyroglobulin labelled with 131I in vivo

1963 • 21 citations

FAILURE TO DEMONSTRATE EXTRATHYRO1DAL THYROXINE FORMATION IN THYROIDECTOMIZED RATS ON LOW AND MODERATE IODINE INTAKES¹

1960 • 21 citations

THE FORMATION OF I¹³¹-MONOIODOTYROSINE FROM I131-IODIDE BY ISOLATED PARTICULATE FRACTIONS OF NON-THYROID TISSUES1

1956 • 20 citations

EFFECT OF VARYING IODINE SUPPLY ON LABELLED IODINE FRACTIONS IN THE THYROID GLAND AFTER I131 ADMINISTRATION

1958 • 19 citations

RADIOIODINE UTILIZATION IN THE CHICK¹

1960 • 19 citations

EFFECTS OF INORGANIC IODIDE ON THE INTERMEDIARY CARBOHYDRATE METABOLISM OF SURVIVING SHEEP THYROID SLICES*

1963 • 19 citations

IN VITRO THYROTROPIN-INDUCED PROTEOLYSIS IN THE THYROID GLAND*

1963 • 19 citations

Some Characteristics of the Sheep Thyroid Gland System for Incorporating Amino Acids Into Protein

1964 • 18 citations

EFFECT OF THYROTROPIN UPON RELEASE OF IODIDE FROM HUMAN AND RAT THYROID*†

1961 • 17 citations

Enzyme Systems Concerned with the Synthesis of Monoiodotyrosine

1961 • 17 citations

Purification of soluble RNA from sheep thyroid gland. Absence of acceptor activity for the iodotyrosines

1964 • 16 citations

Studies on Amino Acid Activating Enzymes in Thyroid Glands1

1964 • 16 citations

Intrathyroidal iodine metabolism in the rat. The iodotyrosines

1963 • 16 citations

Stimulating effects of cytochrome c and quinones on 131I utilization by cell-free sheep thyroid gland preparations

1961 • 16 citations

EFFECT OF THIOCYANATE, STABLE IODIDE AND PERCHLORATE ON THE KINETICS OF RADIOIODIDE TRANSPORT BETWEEN THYROID GLAND AND BLOOD OF RATS¹

1960 • 16 citations

Formation of Thyroglobulin-bound Iodine in Cell-free System and Effect of Thyrotropic Hormone*

1961 • 16 citations

CARBOHYDRATE UTILIZATION BY BEEF THYROID TISSUE

1951 • 16 citations

Nonenzymic synthesis of thyroxine residues in thyroglobulin

1963 • 14 citations

Enzyme systems concerned with the synthesis of monoiodotyrosine. III. Ion requirements of the soluble system.

1961 • 14 citations

Iodine Metabolism in Pig Thyroid Slices and Effect of Thyrotropic Hormone

1961 • 13 citations

PROTEOLYSIS IN PHOSPHATE-PURIFIED THYROGLOBULIN¹²

1960 • 11 citations

Studies on the biosynthesis of iodotyrosines reduced pyridine nucleotide peroxidation by a thyroidal-iodinating enzyme

1962 • 11 citations

Synthesis of 3:3′ diiodothyronine by beef thyroid microsomes

1963 • 11 citations

Action of Pituitary Thyrotropin on the Inorganic Phosphorus of Thyroid Tissue in vitro

1963 • 11 citations

A study of the dialysable lodocompounds of rat thyroid gland

1963 • 10 citations

Gastric Secretion of Iodide at Low Serum Iodide Levels

1950 • 10 citations

IODINE CONTAINING SUBCELLULAR PARTICLES IN THYROID TISSUE¹

1961 • 10 citations

The Oxidation of 3,5-Diiodotyrosine by Peroxidase and Hydrogen Peroxide.

1963 • 10 citations

Synthesis of Thyroxine by L-Amino Acid Oxidase

1962 • 10 citations

THE EARLY PHASE OF THYROID HORMONE FORMATION: STUDIES IN TISSUE SLICES¹

1961 • 9 citations

A Probable Abnormality in Intrathyroidal Iodine Metabolism in Hyperthyroidism¹

1962 • 9 citations

THE EARLY STAGE OF THYROID HORMONE FORMATION: STUDIES ON RAT THYROIDSIN VIVO¹

1961 • 9 citations

Differences in Thyroid Function Between Triiodothyronine-Treated and Hypophysectomized Rats: Binding Glands

1963 • 8 citations

Kinetic Analysis of the Enhanced TSH-Effect on Thyroidal Iodide Transport in Hypophysectomized Rats Fed a Low Iodine Diet

1963 • 8 citations

OXIDATIVE PHOSPHORYLATION AND RESPIRATORY CONTROL IN MITOCHONDRIA FROM NORMAL, ADENOMATOUS, AND HYPERPLASTIC THYROID GLANDS*

1962 • 8 citations

A NOTE ON INORGANIC OXIDATION PRODUCTS OF I¹³¹FORMED IN BIOLOGICAL SYSTEMS¹

1960 • 7 citations

Studies on the Stimulation of Thyroidal Inorganic¹²⁷Iodide Releasein Vitroby Thyrotropin

1964 • 7 citations

Effects of Gamma Radiation on Oxygen Utilization, Iodine Metabolism and Leucine Incorporation by Surviving Sheep Thyroid Tissue Slices

1962 • 7 citations

Influence of ACTH on the Accumulation of Radioiodine in the Human Thyroid—A New Extra-adrenocortical Effect of ACTH

1962 • 7 citations

THE EFFECT OF METHYLTHIOURACIL TREATMENT ON THE HISTOCHEMICALLY DEMONSTRABLE SUCCINIC DEHYDROGENASE ACTIVITY IN THE ORGANS OF THE GUINEA-PIG

1955 • 7 citations

EFFECT OF REPEATED THYROTROPHIN DOSES ON THE UPTAKE OF RADIOACTIVE IODINE BY THE HUMAN THYROID: TIME-RESPONSE RELATIONS

1961 • 6 citations

Iodinated Protein Patterns in Thyroids from Normal and Iodine Deficient Hamsters

1962 • 6 citations

STUDIES ON THE RATIO BETWEEN LABELLED MONOIODOTYROSINE AND LABELLED DIIODOTYROSINE IN THE THYROID GLAND OF RAT AFTER RADIOIODINE ADMINISTRATION

1958 • 6 citations

Synthesis in vitro of thyroxine from diiodotyrosine by myeloperoxidase and by a cell-free preparation of beef thyroid glands II. Flavin mononucleotide and Mn2+ system

1964 • 6 citations

The Effect of Ouabain on Thyrotropin-stimulated Respiration of Thyroid Slices

1963 • 6 citations

Effect of Radiation on the Incorporation of C¹⁴-Formate Into RNA Purines in Calf Thyroid Slicesin Vitro

1962 • 5 citations

Enhancement of thyroidal water content and uptake of 24Na after TSH administration

1960 • 5 citations

INCORPORATION OF IODIDE INTO ORGANIC COMPOUNDS IN THE GUINEA PIG THYROID

1963 • 3 citations

Structural effects in the conversion of side-chain analogs of 3,5-diiodotyrosine to analogs of thyroxine

1958 • 3 citations

Effect of Perchlorate on Iodide in the Thyroids of Rats Receiving Propylthiouracil

1963 • 2 citations