Determination of paclitaxel and metabolites in mouse plasma, tissues, urine and faeces by semi-automated reversed-phase high-performance liquid chromatography

Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

1971 • 3,891 citations

Promotion of microtubule assembly in vitro by taxol

1979 • 3,521 citations

Taxol: A Unique Antineoplastic Agent with Significant Activity in Advanced Ovarian Epithelial Neoplasms

1989 • 1,111 citations

Taxol: A Novel Investigational Antimicrotubule Agent

1990 • 1,084 citations

THE IMPACT OF NATIONAL CANCER ACT

1991 • 809 citations

Phase II Trial of Taxol, an Active Drug in the Treatment of Metastatic Breast Cancer

1991 • 730 citations

Phase I clinical and pharmacokinetic study of taxol.

1987 • 449 citations

Taxol: Mechanisms of Action and Resistancea

1986 • 415 citations

Cytotoxic studies of paclitaxel (Taxol®) in human tumour cell lines

1993 • 402 citations

Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients.

1993 • 311 citations

Phase I trial of taxol given as a 24-hour infusion every 21 days: responses observed in metastatic melanoma.

1987 • 286 citations

Phase I and pharmacodynamic study of taxol in refractory acute leukemias.

1989 • 196 citations

A phase I trial of taxol given by a 6-hour intravenous infusion.

1991 • 185 citations

High-performance liquid chromatographic procedure for the quantitative determination of paclitaxel (Taxol®) in human plasma

1993 • 90 citations

An enzyme immunoassay for the determination of taxol and taxanes in Taxus sp. tissues and human plasma

1993 • 72 citations

Analysis of anticancer drugs in biological fluids: determination of taxol with application to clinical pharmacokinetics

1990 • 64 citations

Steady-state plasma concentrations and effects of taxol for a 250 mg/m2 dose in combination with granulocyte-colony stimulating factor in patients with ovarian cancer

1993 • 62 citations

Characterization of polyclonal and monoclonal anti-taxol antibodies and measurement of taxol in serum.

1993 • 48 citations

Stability problems with taxol in mouse plasma during analysis by liquid chromatography

1993 • 14 citations

Deleted Work

1955 • 0 citations