Rhizoxin binding to tubulin at the maytansine-binding site

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A pharmacokinetic analysis program (multi) for microcomputer.

1981 • 2,465 citations

Molecular aspects of ligand binding to serum albumin.

1981 • 1,504 citations

Tumor inhibitors. LXXIII. Maytansine, a novel antileukemic ansa macrolide from Maytenus ovatus

1972 • 406 citations

[36] Preparation of tubulin from brain

1982 • 395 citations

Ansamitocin, a group of novel maytansinoid antibiotics with antitumour properties from Nocardia

1977 • 208 citations

Studies on macrocyclic lactone antibiotics. VII Structure of a phytotoxin "rhizoxin" produced by Rhizopus chinensis.

1984 • 156 citations

Binding of maytansine to rat brain tubulin

1976 • 123 citations

Rhizoxin, a macrocyclic lactone antibiotic, as a new antitumor agent against human and murine tumor cells and their vincristine-resistant sublines.

1986 • 114 citations

Studies on macrocyclic lactone antibiotics. XI. Anti-mitotic and anti-tubulin activity of new antitumor antibiotics, rhizoxin and its homologues.

1987 • 106 citations

Maytansine binding to the vinblastine sites of tubulin

1977 • 99 citations

Initial studies on the cytotoxic action of maytansine, a novel ansa macrolide

1975 • 61 citations

Different effects of tubulin ligands on the intrachain cross-linking of beta 1-tubulin.

1984 • 58 citations

Studies on macrocyclic lactone antibiotics. VIII. Absolute structures of rhizoxin and a related compound.

1986 • 57 citations

Requirement for ‘Factor(s)’ for Tubulin Assembly during Brain Development

1978 • 51 citations

Contrasting effects of maytansine and vinblastine on the alkylation of tubulin sulfhydryls

1981 • 51 citations

Contrasting roles of tau and microtubule-associated protein 2 in the vinblastine-induced aggregation of brain tubulin.

1984 • 44 citations

Ansamitocins, maytansinoid antitumor antibiotics producing organism, fermentation, and antimicrobial activities.

1980 • 40 citations

[General pharmacology of aclacinomycin A (author's transl)].

1980 • 39 citations

Effect of tau on the vinblastine-induced aggregation of tubulin.

1981 • 38 citations

Evidence for a common high affinity binding site on glutathione S-transferase B for lithocholic acid and bilirubin.

1984 • 33 citations

Effects of new antimitotic antibiotics, ansamitocins, on the growth of murine tumors in vivo and on the assembly of microtubules in vitro.

1980 • 26 citations

Effects of Tau and MAP2 on the interaction of maytansine with tubulin: inhibitory effect of maytansine on vinblastine-induced aggregation of tubulin.

1985 • 25 citations

Biosynthesis of the antimitotic antitumour antibiotic rhizoxin by Rhizopus chinensis; origins of the carbon atoms

1986 • 23 citations

Microbiological Assays and Bioautography of Maytansine and Its Homologues

1974 • 21 citations