Cell cycle-dependent intervention by benzamide of carcinogen-induced neoplastic transformation and in vitro poly(ADP-ribosyl)ation of nuclear proteins in human fibroblasts.

Some current perspectives on chemical carcinogenesis in humans and experimental animals: Presidential Address.

1978 • 938 citations

DNA Modification and Cancer

1981 • 688 citations

Chromosomal Proteins and Chromatin Structure

1975 • 658 citations

Novel inhibitors of poly(ADP-ribose) synthetase

1980 • 519 citations

Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure.

1982 • 499 citations

Enemies within: the genesis of retrovirus oncogenes

1981 • 303 citations

Characterization of a normal avian cell protein related to the avian sarcoma virus transforming gene product

1978 • 251 citations

Three different human tumor cell lines contain different oncogenes

1981 • 245 citations

Metabolic Interconversion of Enzymes

1972 • 228 citations

Isoleucine-mediated regulation of genome repliction in various mammalian cell lines.

1971 • 188 citations

A permeable animal cell preparation for studying macromolecular synthesis. DNA synthesis and the role of deoxyribonucleotides in S phase initiation

1978 • 178 citations

Neoplastic transformation of human diploid cells in vitro after chemical carcinogen treatment

1978 • 164 citations

Cell cycle dependency of oncogenic transformation induced by N-methyl-N'-nitro-N-nitrosoquanidine in culture.

1974 • 159 citations

Interrelationship between poly (ADP-Rib) synthesis, intracellular NAD levels, and muscle or cartilage differentiation from mesodermal cells of embryonic chick limb.

1975 • 158 citations

Mechanisms of syngeneic tumor rejection. Susceptibility of host-selected progressor variants to various immunological effector cells.

1982 • 135 citations

Changes in poly(adenosine diphosphate-ribose) and poly(adenosine diphosphate-ribose) polymerase in synchronous HeLa cells

1976 • 106 citations

Antibody to feline oncornavirus‐associated cell membrane antigen in neonatal cats

1971 • 94 citations

Common antigenic determinants on human melanoma, glioma, neuroblastoma, and sarcoma cells defined with monoclonal antibodies.

1981 • 78 citations

The toxicological evaluation of the mycotoxins T-2 and T-2 tetraol using normal human fibroblasts in vitro

1980 • 66 citations

Methylation of liver DNA guanine in hydrazine hepatotoxicity: dose-response and kinetic characteristics of O⁶-methylguanine and formation and persistence in rats

1981 • 59 citations

Chick Embryonic Skin as a Rapid Organ Culture Assay for Cellular Neoplasia

1978 • 57 citations

Probable helical conformation of poly(ADP-ribose). The effect of cations on spectral properties.

1983 • 55 citations

Spectral analysis of the conformation of polyadenosine diphosphoribose. Evidence indicating secondary structure.

1983 • 54 citations

The in vivo distribution of immunoreactive larger than tetrameric polyadenosine diphosphoribose in histone and non-histone protein fractions of rat liver.

1979 • 52 citations

Poly(ADP-ribosyl)ation of chromosomal proteins in the HeLa S3 cell cycle.

1982 • 51 citations

Characterization of human cells transformed by chemical and physical carcinogens in vitro

1981 • 47 citations

Age-dependent variation of rates of polyadenosine-diphosphoribose synthesis by cardiocyte nuclei and the lack of correlation of enzymatic activity with macromolecular size distribution of DNA.

1981 • 43 citations

Neoplastic transformation of human epithelial cells in vitro after exposure to chemical carcinogens.

1981 • 37 citations

Quantitative isolation of oligo- and polyadenosine-diphosphoribosylated proteins by affinity chromatography from livers of normal and dimethylnitrosamine-treated Syrian hamsters. In vivo and in vitro metabolism of the homopolymer.

1981 • 32 citations

Enhancing effect of 3-aminobenzamide on induction of γ-glutamyl transpeptidase positive foci in rat liver

1982 • 32 citations

Augmentation of carcinogenesis by N-nitrosobis(2-oxopropyl)amine administered during S phase of the cell cycle in regenerating hamster pancreas.

1983 • 29 citations

The effect of in vivo treatment with triiodothyronine on the in vitro synthesis of protein-poly(ADP)-ribose adducts by isolated cardiocyte nuclei and the separation of poly(ADP)-ribosylated proteins by phenol extraction and electrophoresis.

1983 • 26 citations

Induction of Cardiac l-Ornithine Decarboxylase by Nicotinamide and Its Regulation by Putrescine

1978 • 26 citations

Relationship of DNA Tertiary and Quaternary Structure to Carcinogenic Processes

1982 • 25 citations

Translocations Involving Ig-Locus-Carrying Chromosomes: A Model For Genetic Transposition in Carcinogenesis

1982 • 24 citations

The effect of nicotinamide and homologs on the activity of inducible enzymes and NAD content of the rat liver.

1967 • 17 citations

Presensitization of human cells with extrinsic signals to induced chemical carcinogenesis

1980 • 16 citations

The influence of triiodothyronine on polyadenosine-diphosphoribose polymerase and RNA synthesis in cardiocyte nuclei

1982 • 14 citations

Biopsy Measurement of DNA Damage and Repair in Vivo: Single-Strand Breaks, Alkali-Labile Bonds, and Endonuclease-Sensitive Sites

1982 • 14 citations

Biochemical basis of the regulatory role of polyadenosine diphosphoribose

1983 • 14 citations

Benzo[a]pyrene diol epoxide DNA adduct formation in transformable and non-transformable human foreskin fibroblast cells in vitro

1982 • 13 citations

Coincidence of subnuclear distribution of poly(ADP‐ribose) synthetase and DNA polymerase β in nuclei of normal and regenerating liver

1982 • 13 citations

Decrease of hepatic mono and oligo adenosine diphosphoribose content and augmentation of [14C]ribose incorporation during induction of growth by bovine growth hormone in hypophysectomized rats

1981 • 11 citations