Ingested interferon α suppresses Type I diabetes in non-obese diabetic mice

Lymphocyte Homing and Homeostasis

1996 • 2,934 citations

Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases

1995 • 1,120 citations

Type-I Diabetes: A Chronic Autoimmune Disease of Human, Mouse, and Rat

1990 • 650 citations

Genetic Control of Autoimmune Diabetes in the Nod Mouse

1995 • 586 citations

Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice.

1993 • 510 citations

Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice.

1988 • 455 citations

Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice.

1991 • 381 citations

Loss of pancreatic islet tolerance induced by β-cell expression of interferon-γ

1990 • 343 citations

Induction of Type I Diabetes by Interferon-α in Transgenic Mice

1993 • 289 citations

The Regulation of Lymphocyte Traffic

1986 • 285 citations

Prevention of diabetes in NOD mice treated with antibody to murine IFNγ

1991 • 263 citations

Interferon Expression in the Pancreases of Patients With Type I Diabetes

1995 • 244 citations

Transfer of insulin-dependent diabetes between HLA-identical siblings by bone marrow transplantation

1993 • 211 citations

In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice.

1995 • 141 citations

A noncytolytic IL-10/Fc fusion protein prevents diabetes, blocks autoimmunity, and promotes suppressor phenomena in NOD mice.

1997 • 138 citations

Genetic and pathogenic basis of autoimmune diabetes in NOD mice

1994 • 136 citations

Inhibition of T cell responses by activated human CD8+ T cells is mediated by interferon-gamma and is defective in chronic progressive multiple sclerosis.

1995 • 116 citations

Prevention of diabetes in the NOD mouse: implications for therapeutic intervention in human disease

1994 • 108 citations

Circulating Interferon in Rabbits after Administration of Human Interferon by Different Routes

1973 • 95 citations

What Causes Diabetes?

1990 • 93 citations

Reciprocal Allogeneic Bone Marrow Transplantation Between NOD Mice and Diabetes-Nonsusceptible Mice Associated With Transfer and Prevention of Autoimmune Diabetes

1989 • 92 citations

β-Cell Destruction May Be a Late Consequence of the Autoimmune Process in Nonobese Diabetic Mice

1996 • 77 citations

Cross-regulatory role of interferon-gamma (IFN-γ), IL-4 and IL-10 in schistosome egg granuloma formation:in vivoregulation of Th activity and inflammation

1994 • 72 citations

Interferon-induced transfer of viral resistance between animal cells

1977 • 62 citations

PRIMARY NONFUNCTION OF ISLET GRAFTS IN AUTOIMMUNE DIABETIC NONOBESE DIABETIC MICE IS PREVENTED BY TREATMENT WITH INTERLEUKIN-4 AND INTERLEUKIN-101

1996 • 60 citations

Regulation of DTH and IgE responses by IL-4 and IFN-gamma in immunized mice given pertussis toxin.

1994 • 57 citations

Absorption of Cytokines via Oropharyngeal-Associated Lymphoid Tissues

1991 • 53 citations

Type-I Diabetes: A Chronic Autoimmune Disease Of Human, Mouse, And Rat

1990 • 47 citations

The NOD mouse

1994 • 44 citations

Oral administration of human or murine interferon alpha suppresses relapses and modifies adoptive transfer in experimental autoimmune encephalomyelitis

1995 • 42 citations

Regulation of murine macrophage function by IL-4: IL-4 and IFN-gamma differentially regulate macrophage tumoricidal activation.

1993 • 42 citations

Genetic Control of Autoimmune Diabetes in the NOD Mouse

1995 • 42 citations

Reciprocal allogeneic bone marrow transplantation between NOD mice and diabetes-nonsusceptible mice associated with transfer and prevention of autoimmune diabetes

1989 • 37 citations

Antigen presenting cells and the immunogenetics of autoimmune diabetes in NOD mice.

1992 • 37 citations

Beta-cell destruction may be a late consequence of the autoimmune process in nonobese diabetic mice

1996 • 37 citations

Colorectal administration of human interferon-α

1985 • 20 citations

Reciprocal action of interferon‐γ and interleukin‐4 promotes granulomatous inflammation induced by Rhodococcus aurantiacus in mice

1996 • 6 citations