Transplantation of embryonic raphe cells regulates the modifications of the GABAergic phenotype occurring in the injured spinal cord

Two genes encode distinct glutamate decarboxylases

1991 • 1,195 citations

GABA: an excitatory transmitter in early postnatal life

1991 • 1,107 citations

Neurotransmitters as growth regulatory signals: role of receptors and second messengers

1993 • 806 citations

Two Forms of the γ‐Aminobutyric Acid Synthetic Enzyme Glutamate Decarboxylase Have Distinct Intraneuronal Distributions and Cofactor Interactions

1991 • 781 citations

Excitatory GABA Responses in Embryonic and Neonatal Cortical Slices Demonstrated by Gramicidin Perforated-Patch Recordings and Calcium Imaging

1996 • 736 citations

Two isoforms of glutamate decarboxylase: why?

1998 • 610 citations

Regulation of γ‐Aminobutyric Acid Synthesis in the Brain

1993 • 596 citations

The structural and functional heterogeneity of glutamic acid decarboxylase: A review

1991 • 462 citations

Prenatal ontogeny of the gabaergic system in the rat brain: An immunocytochemical study

1986 • 395 citations

Localization and organization of the central pattern generator for hindlimb locomotion in newborn rat

1995 • 380 citations

GABA neurotransmission in the hypothalamus: developmental reversal from Ca2+ elevating to depressing

1995 • 272 citations

Activation of Locomotion in Adult Chronic Spinal Rats Is Achieved by Transplantation of Embryonic Raphe Cells Reinnervating a Precise Lumbar Level

2000 • 250 citations

Excitatory Actions of GABA after Neuronal Trauma

1996 • 235 citations

Changes in GAD- and GABA- immunoreactivity in the spinal dorsal horn after peripheral nerve injury and promotion of recovery by lumbar transplant of immortalized serotonergic precursors

1998 • 181 citations

Direct evidence of an extensive GABAergic innervation of the spinal dorsal horn by fibres descending from the rostral ventromedial medulla

1996 • 175 citations

GABA-induced chemokinesis and NGF-induced chemotaxis of embryonic spinal cord neurons

1994 • 170 citations

Differential regulation of 5‐hydroxytryptamine release by GABA_A and GABA_B receptors in midbrain raphe nuclei and forebrain of rats

1996 • 144 citations

Evidence for nonsynaptic serotonergic and noradrenergic innervation of the rat dorsal horn and possible involvement of neuron-glia interactions

1993 • 144 citations

GABAergic innervation of serotonergic neurons in the dorsal raphe nucleus of the rat studied by electron microscopy double immunostaining

1992 • 142 citations

Extent of colocalization of serotonin and GABA in the neurons of the rat raphe nuclei

1995 • 141 citations

Immunohistochemical evidence for the coexistence of substance P, thyrotropin‐releasing hormone, GABA, methionin‐enkephalin, and leucin‐enkephalin in the serotonergic neurons of the caudal raphe nuclei: A dual labeling in the rat

1991 • 140 citations

Developmental Regulation of Early Serotonergic Neuronal Differentiation: The Role of Brain-Derived Neurotrophic Factor and Membrane Depolarization

1995 • 128 citations

Long term increase of glutamate decarboxylase mRNA in a rat model of temporal lobe epilepsy

1990 • 122 citations

Recovery of locomotor activity in the adult chronic spinal rat after sublesional transplantation of embryonic nervous cells: specific role of serotonergic neurons

1997 • 117 citations

Ultrastructural evidence for GABAergic brain stem projections to spinal motoneurons in the rat

1991 • 114 citations

Transient expression of GABA immunoreactivity in the developing rat spinal cord

1992 • 112 citations

Parallel increases in striatal glutamic acid decarboxylase activity and mRNA levels in rats with lesions of the nigrostriatal pathway

1990 • 111 citations

Messenger RNAs encoding glutamate-decar☐ylases are differentially affected by nigrostriatal lesions in subpopulations of striatal neurons

1992 • 110 citations

Developmental kinetics of GAD family mRNAs parallel neurogenesis in the rat spinal cord

1995 • 108 citations

Direct observations of synapses between GABA-immunoreactive boutons and muscle afferent terminals in lamina VI of the cat's spinal cord

1990 • 101 citations

Immunohistochemical evidence for coexistence of glycine and GABA in nerve terminals on cat spinal motoneurones

1994 • 89 citations

GABAA receptors mediate trophic effects of GABA on embryonic brainstem monoamine neurons in vitro.

1997 • 81 citations

Quantitative analysis of transient GABA expression in embryonic and early postnatal rat spinal cord neurons

1993 • 76 citations

Effects of Increased γ‐Aminobutyric Acid Levels on GAD₆₇ Protein and mRNA Levels in Rat Cerebral Cortex

1993 • 74 citations

The Raphe—Spinal System

1984 • 69 citations

Increased glutamic acid decarboxylase (GAD) mRNA and GAD activity in cerebellar Purkinje cells following lesion-induced increases in cell firing

1990 • 67 citations

Interactions of descending serotonergic systems with other neurotransmitters in the modulation of nociception

1995 • 66 citations

GABA_AReceptors Mediate Trophic Effects of GABA on Embryonic Brainstem Monoamine NeuronsIn Vitro

1997 • 66 citations

Comparative distribution of GAD₆₅ and GAD₆₇ mRNAs and proteins in the rat spinal cord supports a differential regulation of these two glutamate decarboxylases in vivo

1995 • 64 citations

A signal located within amino acids 1-27 of GAD65 is required for its targeting to the Golgi complex region.

1994 • 63 citations

Intraspinal transplants of serotonergic neurons in the adult rat

1989 • 61 citations

Chapter 19 Transplantation of fetal serotonin neurons into the transected spinal cord of adult rats: morphological development and functional influence

1988 • 58 citations

Modulation by GABA of neuroplasticity in the central and peripheral nervous system

1993 • 56 citations

Increased Intracellular γ‐Aminobutyric Acid Selectively Lowers the Level of the Larger of Two Glutamate Decarboxylase Proteins in Cultured GABAergic Neurons from Rat Cerebral Cortex

1992 • 54 citations

In situ hybridization histochemistry: a new method for processing material stored for several years

1992 • 51 citations

A confocal microscopic survey of serotoninergic axons in the lumbar spinal cord of the rat: co-localization with glutamate decarboxylase and neuropeptides

1996 • 50 citations

Fictive motor activities in adult chronic spinal rats transplanted with embryonic brainstem neurons

1995 • 49 citations

Chapter 11 Serotonin, norepinephrine and associated neuropeptides: effects on somatic motoneuron excitability

1996 • 42 citations

Elevation of brain GABA levels with vigabatrin (?-vinylGABA) differentially affects GAD65 and GAD67 expression in various regions of rat brain

1998 • 40 citations

γ-aminobutyric acid enables synaptogenesis in the intact superior cervical ganglion of the adult rat

1985 • 38 citations

Fate of B1–B2 and B3 rhombencephalic cells transplanted into the transected spinal cord of adult rats: Light and electron microscopic studies

1992 • 36 citations

Structural and functional analysis of raphe neurone implants into denervated rat spinal cord

1989 • 29 citations

Transplants of fetal substantia nigra regulate glutamic acid decarboxylase gene expression in host striatal neurons

1991 • 23 citations

Biphasic Response of Spinal GABAergic Neurons after a Lumbar Rhizotomy in the Adult Rat

1996 • 17 citations

Partial deafferentation of the developing rat spinal cord delays the spontaneous repression of GAD67 mRNAs in spinal cells.

1998 • 13 citations

Electronmicroscopic detection of the axonal coexistence of serotonin and substance P in B1-B2 raphé cells transplanted into the transected spinal cord of adult rats

1991 • 13 citations