Functional analysis of a mutant estrogen receptor isolated from T47Deo breast cancer cells

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Sequence and Expression of Human Estrogen Receptor Complementary DNA

1986 • 1,321 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long-term tissue culture.

1976 • 820 citations

An estrogen-responsive element derived from the 5′ flanking region of the Xenopus vitellogenin A2 gene functions in transfected human cells

1986 • 729 citations

A versatilein vivoandin vitroeukaryotic expression vector for protein engineering

1988 • 686 citations

Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor.

1986 • 533 citations

Variant human breast tumor estrogen receptor with constitutive transcriptional activity.

1991 • 397 citations

Oestrogen-responsive human breast cancer in long term tissue culture

1975 • 339 citations

Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance

1982 • 249 citations

Estrogen receptor expression in human breast cancer associated with an estrogen receptor gene restriction fragment length polymorphism.

1989 • 145 citations

Steroid Hormone Receptors in Breast Cancer Treatment Strategy

1980 • 135 citations

Estrogen and progesterone receptor proteins in breast cancer

1979 • 124 citations

T47DCO cells, genetically unstable and containing estrogen receptor mutations, are a model for the progression of breast cancers to hormone resistance.

1990 • 121 citations

Variant Estrogen Receptor mRNA Species Detected in Human Breast Cancer Biopsy Samples

1989 • 111 citations

Oestrogen receptor B-region polymorphism and spontaneous abortion in women with breast cancer

1990 • 111 citations

A Variant Estrogen Receptor Messenger Ribonucleic Acid is Associated with Reduced Levels of Estrogen Binding in Human Mammary Tumors

1988 • 108 citations

Establishment of human endometrial adenocarcinoma cell line containing estradiol-17β and progesterone receptors

1984 • 82 citations

Characterization of estrogen receptor messenger RNA in human breast cancer.

1987 • 79 citations

Genomic DNA analysis of the estrogen receptor gene in breast cancer

1989 • 69 citations

Identification of a variant form of the human estrogen receptor with an amino acid replacement

1989 • 69 citations

A single nucleotide substitution in the D domain of estrogen receptor cDNA causes amino acid alteration from Glu-279 to Lys-279 in a murine transformed leydig cell line (B-1 F)

1991 • 9 citations