The GeneMine system for genome/proteome annotation and collaborative data mining

Basic local alignment search tool

1990 • 87,358 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

A general method applicable to the search for similarities in the amino acid sequence of two proteins

1970 • 11,049 citations

Identification of common molecular subsequences

1981 • 9,753 citations

SCOP: A structural classification of proteins database for the investigation of sequences and structures

1995 • 6,372 citations

The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1999

1999 • 3,156 citations

CATH – a hierarchic classification of protein domain structures

1997 • 2,558 citations

A hidden Markov model for predicting transmembrane helices in protein sequences.

1998 • 2,485 citations

Data mining: an overview from a database perspective

1996 • 2,266 citations

PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization

1999 • 2,159 citations

The PROSITE database, its status in 1997

1997 • 1,783 citations

The PROSITE database, its status in 1999

1999 • 1,109 citations

Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families

1994 • 626 citations

Accurate modeling of protein conformation by automatic segment matching

1992 • 558 citations

The RING finger domain: a recent example of a sequence—structure family

1996 • 464 citations

Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer

1994 • 389 citations

Protein Family Classification Based on Searching a Database of Blocks

1994 • 372 citations

ProDom and ProDom-CG: tools for protein domain analysis and whole genome comparisons

2000 • 372 citations

Solution Structure of the RAIDD CARD and Model for CARD/CARD Interaction in Caspase-2 and Caspase-9 Recruitment

1998 • 302 citations

Cn3D: sequence and structure views for Entrez

2000 • 279 citations

The PROSITE database, its status in 1995

1996 • 266 citations

Reliable identification of large numbers of candidate SNPs from public EST data

1999 • 248 citations

Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization

1994 • 239 citations

The C. elegans gene odr-7 encodes an olfactory-specific member of the nuclear receptor superfamily

1994 • 207 citations

Automated genome sequence analysis and annotation.

1999 • 205 citations

BioKleisli: a digital library for biomedical researchers

1997 • 173 citations

Predicting Protein Mutant Energetics by Self-consistent Ensemble Optimization

1994 • 158 citations

FlyBase: a Drosophila database. Flybase Consortium

1998 • 146 citations

Genome-wide analysis of single-nucleotide polymorphisms in human expressed sequences

2000 • 135 citations

FlyBase: a Drosophila database

1997 • 126 citations

MAGPIE: automated genome interpretation

1996 • 105 citations

PEDANTic genome analysis

1997 • 90 citations

Experimental support for a β-propeller domain in integrin α-subunits and a calcium binding site on its lower surface

1998 • 80 citations

YPD-A database for the proteins of Saccharomyces cerevisiae

1996 • 60 citations

A specific transition state for S-peptide combining with folded S-protein and then refolding

1999 • 51 citations

Characterizing Heterogeneous Molecular Biology Database Systems

1995 • 46 citations

GAIA: Framework Annotation of Genomic Sequence

1998 • 45 citations

Knowledge discovery and data mining in biological databases

1999 • 38 citations

The Effect of Human β2-Microglobulin on Major Histocompatibility Complex I Peptide Loading and the Engineering of a High Affinity Variant

1998 • 26 citations

Comparative visualization of protein structure-sequence alignments

2002 • 5 citations