Association of a variant in exon 31 of the sulfonylurea receptor 1 (SUR1) gene with type 2 diabetes mellitus in French Caucasians

Reconstitution of I _KATP : An Inward Rectifier Subunit Plus the Sulfonylurea Receptor

1995 • 1,703 citations

Cloning of the β Cell High-Affinity Sulfonylurea Receptor: a Regulator of Insulin Secretion

1995 • 1,310 citations

Intracellular ATP directly blocks K+ channels in pancreatic B-cells

1984 • 1,199 citations

Emerging epidemic of type 2 diabetes in youth.

1999 • 1,051 citations

Insulin resistance and hypersecretion in obesity. European Group for the Study of Insulin Resistance (EGIR).

1997 • 877 citations

Mutations in the Sulfonylurea Receptor Gene in Familial Persistent Hyperinsulinemic Hypoglycemia of Infancy

1995 • 812 citations

PATHOGENESIS OF TYPE 2 DIABETES: METABOLIC AND MOLECULAR IMPLICATIONS FOR IDENTIFYING DIABETES GENES

1997 • 701 citations

Time of Onset of Non-Insulin-Dependent Diabetes Mellitus and Genetic Variation in the β₃-Adrenergic–Receptor Gene

1995 • 602 citations

Mutation of the pancreatic islet inward rectifier Kir6.2 also leads to familial persistent hyperinsulinemic hypoglycemia of infancy

1996 • 442 citations

Insulin Resistance versus Insulin Deficiency in Non-Insulin-Dependent Diabetes Mellitus: Problems and Prospects

1998 • 442 citations

ATP-sensitive K + channels and insulin secretion: their role in health and disease

1999 • 435 citations

Linkage of Type 2 Diabetes Mellitus and of Age at Onset to a Genetic Location on Chromosome 10q in Mexican Americans

1999 • 340 citations

Missense mutations in the pancreatic islet beta cell inwardly rectifying K + channel gene (KIR6.2/BIR ): a meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians

1998 • 271 citations

A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene

1997 • 168 citations

Sequence Variants in the Sulfonylurea Receptor (SUR) Gene Are Associated With NIDDM in Caucasians

1996 • 134 citations

Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene.

1998 • 122 citations

Genetic Studies of the Sulfonylurea Receptor Gene Locus in NIDDM and in Morbid Obesity Among French Caucasians

1997 • 97 citations

Sulfonylurea receptor 1 gene variants are associated with gestational diabetes and type 2 diabetes but not with altered secretion of insulin.

2000 • 91 citations

K+ Channels: Generating Excitement in Pancreatic β-Cells

1996 • 90 citations

Variants in the sulphonylurea receptor gene: association of the exon 16-3t variant with Type II diabetes mellitus in Dutch Caucasians

1999 • 87 citations

Disease Associations: Chance, Artifact, or Susceptibility Genes?

1989 • 82 citations

What association analysis can and cannot tell us about the genetics of complex disease

1994 • 77 citations

Variant in sulfonylurea receptor-1 gene is associated with high insulin concentrations in non-diabetic Mexican Americans: SUR-1 gene variant and hyperinsulinemia

1998 • 52 citations

Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM.

1998 • 41 citations

Identification of Microsatellite Markers Near the Human Genes Encoding the β-cell ATP-Sensitive K+ Channel and Linkage Studies with NIDDM in Japanese

1996 • 32 citations

Early‐onset Type 2 Diabetes vs Maturity‐onset Diabetes of Youth: Evidence for the Existence of Two Discrete Diabetic Syndromes

1988 • 25 citations

Linkage studies in NIDDM with markers near the sulphonylurea receptor gene

1995 • 22 citations