Characterization of a CD43/Leukosialin-mediated Pathway for Inducing Apoptosis in Human T-Lymphoblastoid Cells

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes.

1987 • 5,066 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

A gas-liquid solid phase peptide and protein sequenator.

1981 • 2,238 citations

The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death

1994 • 1,920 citations

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1995 • 1,662 citations

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation

1995 • 1,549 citations

Apoptosis of T cells mediated by galectin-1

1995 • 1,056 citations

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

1994 • 726 citations

Human Fas ligand: gene structure, chromosomal location and species specificity

1994 • 435 citations

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

1995 • 411 citations

Immunopathogenesis of the Acquired Immunodeficiency Syndrome

1985 • 333 citations

The dimensions of the T lymphocyte glycoprotein leukosialin and identification of linear protein epitopes that can be modified by glycosylation.

1991 • 266 citations

CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1

1991 • 262 citations

Human thymic epithelial cells express an endogenous lectin, galectin-1, which binds to core 2 O-glycans on thymocytes and T lymphoblastoid cells.

1995 • 260 citations

Negative regulation of T-cell adhesion and activation by CD43

1995 • 236 citations

Identification of a glycophorin-like molecule at the cell surface of rat thymocytes

1981 • 220 citations

Characterization of a human lymphocyte surface sialoglycoprotein that is defective in Wiskott-Aldrich syndrome.

1984 • 203 citations

Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis.

1994 • 184 citations

Two-step TCRζ/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases

1994 • 176 citations

Poly-N-acetyllactosaminyl O-glycans attached to leukosialin. The presence of sialyl Le(x) structures in O-glycans.

1992 • 169 citations

CD43 interferes with T-lymphocyte adhesion.

1992 • 164 citations

Structural variations of O-linked oligosaccharides present in leukosialin isolated from erythroid, myeloid, and T-lymphoid cell lines.

1986 • 156 citations

Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation.

1987 • 145 citations

Morphological abnormalities in the lymphocytes of patients with the Wiskott-Aldrich syndrome

1986 • 143 citations

Regulation of TCR Signaling by CD45 Lacking Transmembrane and Extracellular Domains

1993 • 138 citations

Characterization of cDNAs encoding human leukosialin and localization of the leukosialin gene to chromosome 16.

1989 • 138 citations

CD43 is a murine T cell costimulatory receptor that functions independently of CD28.

1995 • 137 citations

Molecular characterization of sialophorin (CD43), the lymphocyte surface sialoglycoprotein defective in Wiskott-Aldrich syndrome.

1989 • 135 citations

Targeted disruption of CD43 gene enhances T lymphocyte adhesion.

1993 • 134 citations

SURFACE PROTEIN ABNORMALITIES IN LYMPHOCYTES AND PLATELETS FROM PATIENTS WITH WISKOTT-ALDRICH SYNDROME

1981 • 131 citations

Characterization of the activation-associated isoform of CD43 on murine T lymphocytes.

1994 • 129 citations

Induction of aggregation and enhancement of proliferation and IL-2 secretion in human T cells by antibodies to CD43.

1988 • 125 citations

Biosynthesis of truncated O-glycans in the T cell line Jurkat. Localization of O-glycan initiation.

1990 • 123 citations

Granulocytic differentiation of HL-60 cells is associated with increase of poly-N-acetyllactosamine in Asn-linked oligosaccharides attached to human lysosomal membrane glycoproteins

1990 • 120 citations

Rescue of Signaling by a Chimeric Protein Containing the Cytoplasmic Domain of CD45

1993 • 112 citations

Phosphorylation of T cell membrane proteins by activators of protein kinase C.

1988 • 96 citations

T-lymphocytic leukemia expresses complex, branched O-linked oligosaccharides on a major sialoglycoprotein, leukosialin

1991 • 79 citations

Novel approach to affinity chromatography using “weak” monoclonal antibodies

1988 • 77 citations

Deoxyspergualin inhibits kappa light chain expression in 70Z/3 pre-B cells by blocking lipopolysaccharide-induced NF-kappa B activation.

1995 • 77 citations

Expression of a differentiation antigen and poly-N-acetyllactosaminyl O-glycans directed by a cloned core 2 beta-1,6-N-acetylglucosaminyltransferase.

1994 • 75 citations

Persistent repression of a functional allele can be responsible for galactosyltransferase deficiency in Tn syndrome.

1993 • 74 citations

Mechanism of mononuclear cell activation by an anti-CD43 (sialophorin) agonistic antibody.

1989 • 73 citations

Apoptosis of human hematopoietic progenitor cells induced by crosslinking of surface CD43, the major sialoglycoprotein of leukocytes

1995 • 71 citations

Human immunodeficiency virus type 1-infected individuals make autoantibodies that bind to CD43 on normal thymic lymphocytes.

1990 • 67 citations

Protein sequence and gene structure for mouse leukosialin (CD43), a T lymphocyte mucin without introns in the coding sequence

1990 • 67 citations

Signal transduction via leukocyte antigen CD43 (sialophorin). Feedback regulation by protein kinase C.

1990 • 66 citations

Antibodies to the common leukocyte antigen (T200) inhibit an early phase in the activation of resting human B cells.

1987 • 63 citations

Physical associations between CD45 and CD4 or CD8 occur as late activation events in antigen receptor-stimulated human T cells.

1991 • 56 citations

Altered glycosylation of leukosialin, CD43, in HIV-1-infected cells of the CEM line.

1994 • 56 citations

MEM‐59 monoclonal antibody detects a CD43 epitope involved in lymphocyte activation

1995 • 52 citations

Phosphorylation of the major leukocyte surface sialoglycoprotein, leukosialin, is increased by phorbol 12-myristate 13-acetate

1989 • 51 citations

A novel cell surface antigen (T305) found in increased frequency on acute leukemia cells and in autoimmune disease states.

1983 • 51 citations

Structure of the human sialophorin (CD43) gene. Identification of features atypical of genes encoding integral membrane proteins

1990 • 40 citations

Differential Processing and Secretion of the Melanoma-Associated Me20 Antigen

1994 • 37 citations

Differential regulation of CD43 glycoforms on CD4⁺ and CD8⁺ T lymphocytes in graft-versus-host disease

1994 • 37 citations

Lineage-specific Induction of B Cell Apoptosis and Altered Signal Transduction by the Phosphotyrosine Phosphatase Inhibitor Bis(maltolato)oxovanadium(IV)

1995 • 36 citations

Specific regulation of VLA-4 and alpha 4 beta 7 integrin expression on human activated T lymphocytes.

1996 • 34 citations

Separation of blood group A-active oligosaccharides by high-pressure liquid affinity chromatography using a monoclonal antibody bound to concanavalin a silica

1987 • 33 citations

Characterization of a membrane surface glycoprotein associated with T-cell activation.

1985 • 32 citations

Cell membrane perturbation of resting T cells and thymocytes causes display of activation antigens.

1983 • 31 citations

Expression of the Tn antigen on T-lymphoid cell line Jurkat

1991 • 25 citations

Persistent Superphosphorylation of Leukosialin (CD43) in Activated T Cells and in Tumour Cell Lines

1989 • 24 citations

Tn Antigen Is Expressed on Leukosialin from T-Lymphoid Cells

1994 • 19 citations

Separation of oligosaccharides containing terminal α-linked galactose residues by affinity chromatography on Griffonia simplicifolia I bound to concanavalin A-Sepharose

1988 • 17 citations

Role of Cell Surface O-Linked Oligosaccharides in Adhesion of HL60 Cells to Fibronectin: Regulation of Integrin-Dependent Cell Adhesion by O-Linked Oligosaccharide Elongation

1994 • 15 citations

The cell-specific expression of glycan antigens exemplified by the deficiency of β1,3 galactosyltransferase in the Tn-syndrome

1994 • 4 citations