The role of C3 in the immune response

B–cell memory is short-lived in the absence of antigen

1988 • 430 citations

The Role of Complement and Its Receptor in the Elimination of Immune Complexes

1986 • 401 citations

ROLE OF COMPLEMENT IN INDUCTION OF ANTIBODY PRODUCTION IN VIVO

1974 • 357 citations

Synergistic interaction between complement receptor type 2 and membrane IgM on B lymphocytes.

1988 • 260 citations

Growth control of activated, synchronized murine B cells by the C3d fragment of human complement

1985 • 238 citations

Human follicular dendritic cells express CR1, CR2, and CR3 complement receptor antigens.

1985 • 238 citations

The generation of memory cells. I. The role of C3 in the generation of B memory cells.

1977 • 235 citations

The multifunctional role of C3, the third component of complement

1988 • 223 citations

In vivo inhibition of the antibody response by a complement receptor-specific monoclonal antibody.

1990 • 205 citations

The immune complex: possible ways of regulating the antibody response

1990 • 134 citations

Antigen-bound C3b and C4b enhance antigen-presenting cell function in activation of human T-cell clones.

1988 • 121 citations

B-cell activation and HIV-1 infection: Deeds and misdeeds

1990 • 120 citations

Characterization of human T lymphocytes that express the C3b receptor.

1983 • 109 citations

Suppression of T lymphocyte functions by human C3 fragments. I. Inhibition of human T cell proliferative responses by a kallikrein cleavage fragment of human iC3b.

1983 • 93 citations

Mechanisms of Cell-Mediated Cytotoxicity

1982 • 88 citations

Evaluation of the mechanisms responsible for the reduction in erythrocyte complement receptors when immune complexes form in vivo in primates.

1990 • 66 citations

The Bb fragment of complement factor B acts as a B cell growth factor.

1988 • 62 citations

A re-evaluation of the role of C3 in B-cell activation

1986 • 57 citations

Complement fragments suppress lymphocyte immune responses

1982 • 44 citations

Modulation of the Immune Response by Anaphylatoxins

1986 • 38 citations

Clearance of human antibody/DNA immune complexes and free DNA from the circulation of the nonhuman primate

1987 • 37 citations

The Ba fragment of complement factor B inhibits human B lymphocyte proliferation.

1990 • 36 citations

Neutralizing and complement-dependent enhancing antibodies in different stages of HIV infection

1991 • 36 citations

Complement-mediated, infection-enhancing antibodies in plasma from vaccinated macaques before and after inoculation with live simian immunodeficiency virus

1990 • 34 citations

The Clq receptor

1988 • 32 citations

Role of C3b receptors in the enhancement of interleukin-2-dependent T-cell proliferation

1984 • 30 citations

An inherited deficiency of the third component of complement, C3, in guinea pigs

1986 • 28 citations

Secretion, cleavage and binding of complement component C3 by the human monocytic cell line U937

1989 • 26 citations

Studies on the possible involvement of complement component C3 in the initiation of acid hydrolase secretion by macrophages.

1982 • 22 citations

Synthesis of the third component of complement (C3) by lectin-activated and HTLV-infected human T-cells

1990 • 22 citations

The third component of complement (C3) bound to tumor target cells enhances their sensitivity to killing by activated macrophages.

1987 • 22 citations

Appearance of acceptor-bound C3b on HLA-DR positive macrophages and on stimulated U937 cells; Inhibition of Fcγ-receptors by the covalently fixed C3 fragments

1988 • 19 citations

Interactions between murine B lymphocyte surface membrane molecules. Loaded but not free receptors for complement and the Fc portion of IgG co-cap independently with cross-linked surface Ig.

1990 • 12 citations

Interaction between C3 and IL-2; inhibition of C3b binding to CR1 by IL-2

1989 • 12 citations

A Possible Self‐Regulating Mechanism Mediated by C3b‐Acceptor‐Bound C3b Generated by Stimulated Macrophages

1985 • 10 citations

BSA-anti-BSA immune complexes formed in the presence of human complement do not bind to autologous red blood cells.

1988 • 10 citations

C3, C4, and the terminal complement complex differ from C1q by binding predominantly to the antigenic part of solid phase immune complexes.

1990 • 9 citations

The Mechanisms of Cell-Mediated Cytotoxicity

1981 • 8 citations

Immunohistochemical localization of a plasma protein (glycoprotein 60) which inhibits complement-mediated prevention of immune precipitation.

1990 • 8 citations

Interference of a C3-fragment preparation with IL 2-dependent proliferation.

1986 • 7 citations

Evidences proving the intercalation hypothesis of the C-mediated complex release activity (CRA)

1978 • 5 citations

Differences in the Complement Activation Induced by Preformed and Nascent Immune Complexes

1991 • 5 citations