Transforming growth factor β1 is associated with angiogenesis, metastasis, and poor clinical outcome in prostate cancer

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Transforming Growth Factor β in Tissue Fibrosis

1994 • 3,055 citations

The Transforming Growth Factor-beta Family

1990 • 3,028 citations

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor

1993 • 779 citations

Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells.

1994 • 702 citations

Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane.

1990 • 470 citations

Genetic changes in the transforming growth factor beta (TGF-beta) type II receptor gene in human gastric cancer cells: correlation with sensitivity to growth inhibition by TGF-beta.

1994 • 431 citations

Expression of Transforming Growth Factor-β in the Rat Ventral Prostate during Castration-Induced Programmed Cell Death

1989 • 417 citations

A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance.

1990 • 409 citations

Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential.

1990 • 398 citations

Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes.

1989 • 378 citations

Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells

1994 • 325 citations

Transforming growth factor-beta inhibits endothelial cell proliferation

1986 • 313 citations

Inhibition of endothelial cell proliferation by type β-transforming growth factor: Interactions with acidic and basic fibroblast growth factors

1986 • 312 citations

Strategies for improving the immunohistochemical staining of various intranuclear prognostic markers in formalin-paraffin sections: Androgen receptor, estrogen receptor, progesterone receptor, p53 protein, proliferating cell nuclear antigen, and Ki-67 antigen revealed by antigen retrieval techniques

1994 • 271 citations

Transforming growth factor-beta 1 overproduction in prostate cancer: effects on growth in vivo and in vitro.

1992 • 242 citations

TGF‐β Receptors and TGF‐β Binding Proteoglycans: Recent Progress in Identifying Their Functional Properties

1990 • 233 citations

Transforming growth factor-beta 1 mediates mast cell chemotaxis.

1994 • 223 citations

Effect of Transforming Growth Factor-β¹on Proliferation and Death of Rat Prostatic Cells*

1990 • 218 citations

Genetic change in transforming growth factor beta (TGF-beta) receptor type I gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cells.

1996 • 195 citations

Association of transforming growth factor-β1 with prostate cancer: An immunohistochemical study

1993 • 170 citations

Loss of expression of transforming growth factor beta type I and type II receptors correlates with tumor grade in human prostate cancer tissues.

1996 • 167 citations

Transforming growth factor β stimulates mamary adenocarcinoma cell invasion and metastasis potential

1990 • 164 citations

Intron-exon structure of the human transforming growth factor-β precursor gene

1987 • 159 citations

Control of human glioma cell growth, migration and invasion in vitro by transforming growth factor β1

1994 • 150 citations

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1995 • 147 citations

Vascular density is a predictor of cancer-specific survival in prostatic carcinoma

1997 • 138 citations

Down-regulation of protein and mRNA expression for transforming growth factor-β (TGF-β1) type I and type II receptors in human prostate cancer

1997 • 130 citations

Expression of transforming growth factor-beta 1 in prostate cancer.

1994 • 128 citations

Vascular endothelial growth factor production is stimulated by gangliosides and TGF-β isoforms in human glioma cells in vitro

1996 • 117 citations

Transforming growth factor-beta 1: comparative immunohistochemical localization in human primary and metastatic prostate cancer.

1995 • 108 citations

Incidence of apoptosis and cell proliferation in prostate cancer: Relationship with TGF-β1 and bcl-2 expression

1996 • 104 citations

Cell Proliferation Assessed by Ki-67 Immunoreactivity on Formalin Fixed Tissues is a Predictive Factor for Survival in Prostate Cancer

1997 • 87 citations

Transforming growth factor beta1 induces angiogenesis in vivo with a threshold pattern.

1996 • 85 citations

Reduced levels of transforming growth factor beta receptor type II in human prostate cancer: an immunohistochemical study.

1996 • 84 citations

Transforming growth factor beta1 stimulates contrasting responses in metastatic versus primary mouse prostate cancer-derived cell lines in vitro.

1996 • 83 citations

Heparin-binding growth factor/prostatropin attenuates inhibition of rat prostate tumor epithelial cell growth by transforming growth factor type beta

1988 • 80 citations

Interaction of epidermal growth factor and transforming growth factor beta in human prostatic epithelial cells in culture

1992 • 79 citations

Modulation of transforming growth factor beta 1 effects on prostate cancer cell proliferation by growth factors and extracellular matrix.

1995 • 78 citations

Transforming growth factor β1 as a biomarker for prostate cancer

1992 • 71 citations

Effect of TGF-beta 1, TGF-alpha, and EGF on cell proliferation and cell death in rat ventral prostatic epithelial cells in culture.

1995 • 70 citations

Laparoscopic Bilateral Nephrectomy: Results in 11 Renal Transplant Patients

1997 • 67 citations

Effect of TGF‐β1, TGF‐α, and EGF on Cell Proliferation and Cell Death in Rat Ventral Prostatic Epithelial Cells in Culture

1995 • 51 citations

Mesenchymal‐epithelial interactions and transforming growth factor‐β1 expression during normal and abnormal prostatic growth

1995 • 35 citations

Divergent effect of TGFβ1 on growth and proteolytic modulation of human prostatic-cancer cell lines

1996 • 25 citations

Expression of transforming growth factor-? receptor type I and type II in rat ventral prostate and Dunning R3327 PAP adenocarcinoma in response to castration and oestrogen treatment

1997 • 17 citations

Prostate cancer cells lose their sensitivity to TGFβI growth inhibition with tumor progression

1995 • 12 citations

Role of prostatic basal cells in the regulation and suppression of human prostate cancer cells

1996 • 12 citations

Long-Term Outcome of Conservative Therapy in Men Presenting with Voiding Symptoms and Prostate Cancer

1997 • 11 citations