Metabolism and functions of cyclic amp in nerve

Adenosine 3‘,5‘-Phosphate in Biological Materials

1962 • 2,102 citations

An Adenosine 3′,5′-Monophosphate-dependant Protein Kinase from Rabbit Skeletal Muscle

1968 • 1,423 citations

Advances in biochemical psychopharmacology

1970 • 1,186 citations

Cell Communication, Calcium Ion, and Cyclic Adenosine Monophosphate

1970 • 1,097 citations

FRACTIONATION AND CHARACTERIZATION OF A CYCLIC ADENINE RIBONUCLEOTIDE FORMED BY TISSUE PARTICLES

1958 • 1,055 citations

Multiple cyclic nucleotide phosphodiesterase activities from rat brain

1971 • 1,054 citations

Some Aspects of the Biological Role of Adenosine 3',5'-monophosphate (Cyclic AMP)

1968 • 976 citations

The effect of adenosine and adenine nucleotides on the cyclic adenosine 3', 5'-phosphate content of guinea pig cerebral cortex slices.

1970 • 860 citations

Adenyl Cyclase

1962 • 853 citations

Cyclic 3′,5′-nucleotide phosphodiesterase

1970 • 824 citations

Purification and Properties of Rabbit Skeletal Muscle Adenosine 3',5'-Monophosphate-dependent Protein Kinases

1971 • 810 citations

CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASES, IV. WIDESPREAD OCCURRENCE OF ADENOSINE 3′,5′-MONOPHOSPHATE-DEPENDENT PROTEIN KINASE IN VARIOUS TISSUES AND PHYLA OF THE ANIMAL KINGDOM

1969 • 775 citations

ADENYL CYCLASE AS AN ADRENERGIC RECEPTOR*

1967 • 682 citations

Radioimmunoassay for Cyclic Nucleotides

1972 • 582 citations

The role of cyclic-3',5'-AMP in responses to catecholamines and other hormones.

1966 • 573 citations

Cyclic Nucleotide-dependent Protein Kinases

1969 • 551 citations

Calcium dependent phosphodiesterase activity and its activating factor (PAF) from brain

1970 • 491 citations

A RADIOISOTOPIC METHOD FOR MEASURING THE FORMATION OF ADENOSINE 3′,5′‐CYCLIC MONOPHOSPHATE IN INCUBATED SLICES OF BRAIN

1969 • 471 citations

Effects of xanthine derivatives on lipolysis and on adenosine 3',5'-monophosphate phosphodiesterase activity.

1970 • 462 citations

Elevation of Guanosine 3′,5′-Cyclic Phosphate in Rat Heart after Perfusion with Acetylcholine

1970 • 455 citations

The influence of chemical agents on the accumulation of adenosine 3',5'-Phosphate in slices of rabbit cerebellum.

1968 • 435 citations

THE ACTION OF EPINEPHRINE AND THE ROLE OF THE ADENYL CYCLASE SYSTEM IN HORMONE ACTION.

1965 • 423 citations

Lesions of Central Norepinephrine Terminals with 6-OH-Dopamine: Biochemistry and Fine Structure

1969 • 421 citations

Adenyl Cyclase

1962 • 415 citations

Dopamine-Sensitive Adenyl Cyclase: Possible Role in Synaptic Transmission

1971 • 415 citations

Guanyl Cyclase, an Enzyme Catalyzing the Formation of Guanosine 3',5'-Monophosphate from Guanosine Triphosphate

1969 • 391 citations

A cyclic-3′,5′-adenosine monophosphate dependent protein kinase from the adrenal cortex: Comparison with a cyclic AMP binding protein

1970 • 382 citations

Assay of adenosine 3',5'-cyclic monophosphate and guanosine 3',5'-cyclic monophosphate in biological materials by enzymic radioisotopic displacement

1968 • 369 citations

Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. II. Sensitivity of Purkinje cells to norepinephrine and related substances administered by microiontophoresis

1971 • 354 citations

Subcellular Distribution of Adenyl Cyclase and Cyclic Phosphodiesterase in Rat Brain Cortex

1967 • 337 citations

Isolation of adenosine 3′,5′-monophosphate and guanosine 3′,5′-monophosphate from rat urine

1963 • 335 citations

Cyclic Nucleotide-dependent Protein Kinases

1970 • 334 citations

Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. I. Localization of the fibers and their synapses

1971 • 334 citations

Role of Muscarinic Cholinergic Receptors in Regulation of Guanosine 3′:5′-Cyclic Monophosphate Content in Mammalian Brain, Heart Muscle, and Intestinal Smooth Muscle

1972 • 327 citations

Hydrolysis of Cyclic Guanosine and Adenosine 3',5'-Monophosphates by Rat and Bovine Tissues

1970 • 303 citations

Properties of Cyclic 3',5'-Nucleotide Phosphodiesterase from Rat Brain^*

1967 • 297 citations

Characterization of Cyclic Nucleotide Phosphodiesterases of Rat Tissues

1971 • 297 citations

THE EFFECT OF ELECTRICAL STIMULATION UPON THE ACCUMULATION OF ADENOSINE 3′,5′‐PHOSPHATE IN ISOLATED CEREBRAL TISSUE

1969 • 294 citations

Stimulation by Dopamine of Adenylate Cyclase in Retinal Homogenates and of Adenosine-3′:5′-Cyclic Monophosphate Formation in Intact Retina

1972 • 286 citations

Cyclic Nucleotide-dependent Protein Kinases

1972 • 282 citations

Determination of Guanosine 3',5'-Monophosphate in Tissues and of Guanyl Cyclase in Rat Intestine

1969 • 281 citations

Stimulation of Adenosine 3',5'-Monophosphate Hydrolysis by Guanosine 3',5'-Monophosphate

1971 • 275 citations

Electrical activity of vertebrate photoreceptors

1970 • 260 citations

Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. III. Evidence for mediation of norepinephrine effects by cyclic 3′, 5′-adenosine monophosphate

1971 • 257 citations

Separation of regulatory and catalytic subunits of the cyclic 3′, 5′-adenosine monophosphate-dependent protein kinase(s) of rabbit skeletal muscle

1971 • 253 citations

Effect of Catecholamines on the Adenosine 3′:5′-Cyclic Monophosphate Concentrations of Clonal Satellite Cells of Neurons

1971 • 245 citations

Adenosine 3′,5′-Monophosphate: Electrophysiological Evidence for a Role in Synaptic Transmission

1972 • 243 citations

Cyclic Adenosine Monophosphate and Norepinephrine: Effects on Transmembrane Properties of Cerebellar Purkinje Cells

1971 • 230 citations

Cyclic adenosine monophosphate, CA++, and membranes.

1968 • 228 citations

REGIONAL ENERGY RESERVES IN MOUSE BRAIN AND CHANGES WITH ISCHAEMIA AND ANAESTHESIA*

1966 • 227 citations

Studies on adenosine 3',5'-phosphate in rabbit cerebral cortex.

1968 • 224 citations

Mode of action of adenosine 3′,5′-cyclic phosphate on protein kinase from rat liver

1970 • 224 citations

The effect of oxotremorine and atropine on cGMP and cAMP levels in mouse cerebral cortex and cerebellum

1970 • 224 citations

Chemical synthesis and biological activity of 8-substituted adenosine 3',5'-cyclic monophosphate derivatives

1971 • 217 citations

CONTROL OF GLYCOGEN LEVELS IN BRAIN¹

1968 • 216 citations

Detection of guanyl cyclase in mammalian tissues

1969 • 215 citations

Cyclic Guanosine 3′,5′-Monophosphate in Mammalian Tissues and Urine

1969 • 212 citations

A cyclic 3′,5′-AMP-stimulated protein kinase from cardiac muscle

1970 • 211 citations

The Role of Cyclic AMP and Calcium in Cell Activatio

1972 • 209 citations

Subcellular Distribution of Adenosine 3',5'-Monophosphate-dependent Protein Kinase in Rat Brain

1971 • 208 citations

Cyclic Adenosine Monophosphate Phosphodiesterase in Brain: Effect on Anxiety

1972 • 207 citations

Enzymatic Hydrolysis of Adenosine 3',5'-Phosphoric Acid

1961 • 206 citations

Cyclic Adenosine 3′:5′-Monophosphate-Stimulated Phosphorylation of Isolated Neurotubule Subunits

1970 • 206 citations

Adenosine 3′,5′-Monophosphate in Nervous Tissue: Increase Associated with Synaptic Transmission

1971 • 205 citations

Cyclic Adenosine Monophosphate: Possible Mediator for Norepinephrine Effects on Cerebellar Purkinje Cells

1969 • 195 citations

Phosphorylation of Endogenous Protein of Rat Brain by Cyclic Adenosine 3′,5′-Monophosphate-dependent Protein Kinase

1971 • 192 citations

Cyclic nucleotide-dependent protein kinases. V. Preparation and properties of adenosine 3′,5′-monophosphate-dependent protein kinase from various bovine tissues

1970 • 189 citations

Stimulated Formation of Adenosine 3′,5′-Cyclic Phosphate in Cerebral Cortex: Synergism between Electrical Activity and Biogenic Amines

1970 • 189 citations

Adenosine 3′,5-Monophosphatedependent Phosphorylation of a Specific Protein in Synaptic Membrane Fractions from Rat Cerebrum

1972 • 177 citations

EFFECTS OF CONVULSANTS ON ENERGY RESERVES IN THE CEREBRAL CORTEX *

1967 • 177 citations

Hormone-Sensitive Adenyl Cyclase: Cytochemical Localization in Rat Liver

1970 • 174 citations

Cyclic Adenosine Monophosphate in the Nervous System of Aplysia californica

1972 • 173 citations

Papaverine - induced inhibition of phosphodiesterase activity in various mammalian tissues

1971 • 172 citations

Cyclic Nucleotide-dependent Protein Kinases

1971 • 171 citations

Phosphoprotein Phosphatases from Rat Cerebral Cortex

1972 • 169 citations

CYTOCHEMICAL LOCALIZATION OF ADENYL CYCLASE ACTIVITY IN RAT ISLETS OF LANGERHANS

1972 • 168 citations

Regulation of Adenosine 3′,5′-Cyclic Monophosphate Metabolism in Cultured Neuroblastoma Cells

1971 • 168 citations

Regulation of Adenosine 3′:5′-Cyclic Monophosphate Concentration in Cultured Human Astrocytoma Cells by Catecholamines and Histamine

1971 • 168 citations

Cyclic Adenosine Monophosphate in Brain Areas: Microwave Irradiation as a Means of Tissue Fixation

1971 • 161 citations

Regional and subcellular distribution of adenyl cyclase and 3',5'-cyclic nucleotide phosphodiesterase in brain and pineal gland

1968 • 161 citations

Cyclic 3′,5′-Nucleotide Phosphodiesterase: Cytochemical Localization in Cerebral Cortex

1971 • 159 citations

Separation of multiple molecular forms of cyclic adenosine-3′,5′-monophosphate phosphodiesterase in rat cerebellum by polyacrylamide gel electrophoresis

1972 • 156 citations

Adenyl Cyclase Activity in Rat Pineal Gland: Effects of Chronic Denervation and Norepinephrine

1967 • 155 citations

3',5' CYCLIC ADENOSINE MONOPHOSPHATE IN DEPRESSION AND MANIA

1970 • 154 citations

EVIDENCE FOR A ROLE OF CYCLIC AMP IN NEUROMUSCULAR TRANSMISSION

1969 • 153 citations

THE MEASUREMENT OF CYCLIC ADENYLATE IN TISSUES

1964 • 152 citations

Adenyl Cyclase as a Link between Photon Capture and Changes in Membrane Permeability of Frog Photoreceptors

1971 • 152 citations

Effects of lithium on brain adenyl cyclase activity

1971 • 151 citations

Adenyl Cyclase of Rat Cerebral Cortex

1971 • 151 citations

SELECTIVE STIMULATION OF ADENYL CYCLASE OF RAT PINEAL GLAND BY PHARMACOLOGICALLY ACTIVE CATECHOLAMINES

1968 • 148 citations

Radioimmunoassay for the measurement of cyclic nucleotides.

1972 • 148 citations

Adenosine 3′,5′-Monophosphate-Dependent Protein Kinase from Brain

1969 • 147 citations

Stimulation by Cyclic AMP of Intrinsic Protein Kinase Activity in Ox Brain Membrane Preparations

1970 • 145 citations

Cyclic Adenosine 3′,5′-Monophosphate in Guinea Pig Cerebral Cortical Slices

1973 • 143 citations

α- and β-Adrenergic Receptors as Mediators of Accumulation of Cyclic Adenosine 3',5'-Monophosphate in Specific Areas of Guinea Pig Brain

1971 • 143 citations

Activation of a Central Noradrenergic Projection to Cerebellum

1971 • 142 citations

Cyclic Adenosine Monophosphate Stimulation of Axonal Elongation

1972 • 135 citations

THE SWITCH PROCESS FROM DEPRESSION TO MANIA: RELATIONSHIP TO DRUGS WHICH ALTER BRAIN AMINES

1970 • 130 citations

Ionic and hormonal control of calcium homeostasis

1971 • 126 citations

INCREASE IN THE CONTENT OF ADENOSINE 3′5′‐ MONOPHOSPHATE IN MOUSE FOREBRAIN DURING SEIZURES AND PREVENTION OF THE INCREASE BY METHYLXANTHINES

1971 • 126 citations

Cyclic AMP and adenyl cyclase in the developing rat brain

1970 • 125 citations

Cyclic 3′, 5′-nucleotide phosphodiesterase: Pronounced stimulation by snake venom

1967 • 125 citations

Regulation of Glycolysis in Brain, in Situ, during Convulsions

1966 • 123 citations

Cyclic Nucleotide Phosphodiesterase: High Activity in a Mammalian Photoreceptor

1972 • 115 citations

Effect of Norepinephrine, Histamine and Other Drugs on Cyclic 3’, 5’-AMP Formation in Brain Slices of Various Animal Species

1971 • 113 citations

The Kinetics of Glycogen Phosphorylases from Brain and Muscle

1967 • 112 citations

Effect of Norepinephrine on the Concentration of Adenosine 3′,5′-Monophosphate of Rat Pineal Gland in Organ Culture

1972 • 109 citations

Measurement of Guanosine 3‘,5‘-Monophosphate and Other Cyclic Nucleotides

1966 • 108 citations

3′, 5′-Cyclic nucleotide phosphodiesterase

2001 • 108 citations

Turnover of protein-bound phosphorylserine in membrane preparations from ox brain catalysed by intrinsic kinase and phosphatase activity

1971 • 108 citations

High activity of adenyl cyclase in olfactory and gustatory organs

1972 • 108 citations

Adenosine 3′,5′-Monophosphate Phosphodiesterase: Multiple Molecular Forms

1971 • 105 citations

CHEMICAL CHANGES IN THE BRAIN DURING INSULIN HYPOGLYCAEMIA AND RECOVERY*

1965 • 104 citations

Theophylline, epinephrine, and neostigmine facilitation of neuromuscular transmission.

1967 • 102 citations

The effect of Ca2+ on the adenyl cyclase of calf brain

1970 • 100 citations

A protein kinase activity from rat cerebellum stimulated by guanosine-3′:5′-monophosphate

1972 • 100 citations

Increased cyclic AMP response to norepinephrine in the rat brain following 6-hydroxydopamine

1972 • 99 citations

Cyclic Adenosine Monophosphate in the Nervous System of Aplysia californica

1972 • 97 citations

Accumulation of cyclic adenosine monophosphate in incubated slices of brain tissue. 2. Effects of depolarizing agents, membrane stabilizers, phosphodiesterase inhibitors, and adenosine analogs

1972 • 97 citations

Formation of cyclic adenosine 3′,5′-monophosphate from adenosine in brain slices

1970 • 97 citations

Physiological and drug‐induced changes in the glycogen content of mouse brain

1970 • 96 citations

Effects of phenothiazine tranquilizers on the cyclic 3′,5′-adenosine monophosphate system of rat brain

1971 • 94 citations

Pineal gland: stimulation of melatonin production by norepinephrine involves cyclic AMP-mediated stimulation of N-acetyltransferase.

1970 • 93 citations

Adenosine cyclic 3',5'-monophosphate in fetal rat brain cell cultures. I. Effect of catecholamines.

1972 • 92 citations

Analogues of 4-(3,4-dimethoxybenzyl)-2-imidazolidinone as potent inhibitors of rat erythrocyte adenosine cyclic 3',5'-phosphate phosphodiesterase.

1971 • 92 citations

Cyclic 3′,5′-nucleotide phosphodiesterase, IV. Two enzymes with different properties from brain

1971 • 92 citations

Cyclic 3′,5′-Nucleotide Phosphodiesterase: Localization and Latent Activity in Rat Brain

1967 • 91 citations

Inhibition of cyclic 3′,5′-nucleotide phosphodiesterase by phenothiazine and reserpine derivatives

1968 • 90 citations

GLYCOGEN PHOSPHORYLASE IN BRAIN*

1962 • 89 citations

A METHOD FOR DETECTING INTRACELLULAR CYCLIC ADENOSINE MONOPHOSPHATE BY IMMUNOFLUORESCENCE

1972 • 86 citations

Cyclic adenosine 3',5'-monophosphate formation in brain slices: stimulation by batrachotoxin, ouabain, veratridine, and potassium ions.

1970 • 86 citations

Cyclic AMP in brain areas: Effects of amphetamine and norepinephrine assessed through the use of microwave radiation as a means of tissue fixation

1972 • 82 citations

Cyclic AMP and Drug Action

1970 • 82 citations

Cyclic Adenosine Monophosphate: Function in Photoreceptors

1971 • 82 citations

The Properties of Glycogen Synthetase and Regulation of Glycogen Biosynthesis in Rat Brain

1969 • 82 citations

ONTOGENETIC DEVELOPMENT OF ADENYL CYCLASE AND PHOSPHODIESTERASE IN RAT BRAIN

1971 • 82 citations

Activation of insect nerve cord phosphorylase by octopamine and adenosine 3′,5′‐monophosphate

1972 • 81 citations

Role of adenosine 3',5'-monophosphate (cyclic AMP) in actions of catecholamines.

1972 • 81 citations

Stimulation of the Activity of Cyclic 3', 5'-Nucleotide Phosphodiesterase by Calcium Ion

1970 • 78 citations

Inhibition of cyclic nucleotide phosphodiesterase by adenosine 5′-triphosphate and inorganic pyrophosphate

1966 • 78 citations

Effects of environmental lighting and chronic denervation on the activation of adenyl cyclase of rat pineal gland by norepinephrine and sodium fluoride.

1969 • 77 citations

On the mechanism of action of cyclic AMP and its role in synaptic transmission.

1972 • 76 citations

Effect of depolarizing agents on accumulation of cyclic adenosine 3′, 5′-monophosphate in cerebral cortical slices

1972 • 74 citations

CYCLIC 3',5'-NUCLEOTIDE PHOSPHODIESTERASE IN BRAIN

1969 • 74 citations

MICROASSAY OF ADENOSINE‐3′,5′‐MONOPHOSPHATE (CYCLIC AMP) IN BRAIN AND OTHER TISSUES BY THE LUCIFERIN‐LUCIFERASE SYSTEM¹

1971 • 70 citations

Organophosphates of urine, including adenosine 3′,5′-monophosphate and guanosine 3′,5′-monophosphate

1967 • 68 citations

Gonadal Hormones as Regulators of Pineal Adenyl Cyclase Activity

1970 • 67 citations

Adenosine 3′,5′-Monophosphate Is Localized in Cerebellar Neurons: Immunofluorescence Evidence

1972 • 67 citations

Accumulation of Adenosine 3′:5′-Cyclic Monophosphate in Clonal Glial Cells: Labeling of Intracellular Adenine Nucleotides with Radioactive Adenine

1972 • 66 citations

3′:5′-Cyclic Adenosine Monophosphate Phosphodiesterase: Negative Cooperativity

1972 • 66 citations

Accumulation of cyclic adenosine monophosphate in incubated slices of brain tissue. 1. Structure-activity relation of agonists and antagonists of biogenic amines and of tricyclic tranquilizers and antidepressants

1972 • 65 citations

Dibutyryl Cyclic Adenosine Monophosphate Stimulation of Colcemid-Inhibited Axonal Elongation

1972 • 65 citations

Factors influencing the accumulation of cyclic AMP in brain tissue.

1970 • 64 citations

Norepinephrine Stimulated Increase of Cyclic AMP Levels in Developing Mouse Brain Cell Cultures

1971 • 64 citations

Prostaglandins E ₁ and E ₂ Antagonize Norepinephrine Effects on Cerebellar Purkinje Cells: Microelectrophoretic Study

1969 • 64 citations

Histochemical method for localization of cyclic 3?, 5?-nucleotide phosphodiesterase

1966 • 64 citations

Urinary Adenosine 3′,5′-Monophosphate in the Switch Process from Depression to Mania

1971 • 63 citations

Brain glycogen phosphorylase

1964 • 61 citations

Structure-activity relationships for inhibitors of phosphodiesterase from erythrocytes and other tissues.

1972 • 61 citations

Comparison of the effects of Ca2+ and Mg2+ on the adenyl cyclase of beef brain

1972 • 59 citations

THE CONVERSION OF PHOSPHORYLASE b TO PHOSPHORYLASE a IN BRAIN*

1965 • 58 citations

Urinary Adenosine 3', 5'-Monophosphate Excretion in Affective Disorders

1970 • 58 citations

CATECHOLAMINE INDUCED INCREASE OF CYCLIC ADENOSINE 3′,5′‐MONOPHOSPHATE IN RAT BRAIN IN VIVO

1972 • 57 citations

Different sensitivities of the phosphodiesterases (adenosine-3′,5′-cyclic phosphate 3′-phosphohydrolase) of dog cerebral cortex and erythrocytes to inhibition by synthetic agents and cold

1971 • 57 citations

Some properties of cyclic 3′, 5′-nucleotide phosphodiesterase of mouse brain: effects of imidazole-4-acetic acid, chlorpromazine, cyclic 3′,5′-GMP, and other substances

1970 • 57 citations

Coordination Polymers of Osmium: The Nature of Osmium Black

1967 • 57 citations

Effects of catecholamines and monovalent cations on adenylate cyclase activity in cultured glial tumor cells

1971 • 56 citations

Cyclic 3′,5′-nucleotide phosphodiesterase effect of divalent cations

1971 • 53 citations

EFFECT OF CONVULSANTS ON BRAIN GLYCOGEN IN THE MOUSE*

1961 • 52 citations

On the mechanism of action of cyclic AMP.

1970 • 52 citations

Analogues of adenosine 3',-5'-cyclic phosphate as activators of phosphorylase b kinase and as substrates for cyclic 3',5'-nucleotide phosphodiesterase.

1970 • 51 citations

STUDIES ON PHOSPHORYLASE b KINASE FROM NEUTRAL TISSUES

1970 • 51 citations

The measurement of cyclic nucleotides by radioimmunoassay.

1970 • 51 citations

The Effect of Centrally Acting Drugs on the Concentration of Brain Adenosine 3’, 5’-Monophosphate

1970 • 51 citations

Cyclic adenosine 3′:5′-monophosphate and microtubule function: Specific interaction of the phosphorylated protein subunits with a soluble brain component

1971 • 50 citations

Adenyl Cyclase and Phosphodiesterase Activities in Brain Areas of Man, Monkey and Rat

1969 • 50 citations

The effect of histamines and other compounds on the formation of adenosine 3′,5′‐monophosphate in slices from cerebral cortex

1970 • 49 citations

Modification by psychotropic drugs of the cyclic adenosine monophosphate response to norepinephrine in rat brain

1971 • 49 citations

Digitonin Effects on Photoreceptor Adenylate Cyclase

1972 • 48 citations

Cyclic Adenylate and Hypothalamic Regulatory Functions

1969 • 47 citations

CYCLIC A.M.P. IN AFFECTIVE DISORDERS

1970 • 46 citations

Pineal Gland in Organ Culture. II. Role of Adenosine 3′,5′-Monophosphate in the Regulation of Radiolabeled Melatonin Production

1971 • 44 citations

EFFECTS OF ELECTRICAL STIMULATION ON METABOLITES IN BRAIN OF DECAPITATED MICE

1967 • 44 citations

DEVELOPMENT AND CHARACTERISTICS OF THE HISTAMINE‐INDUCED ACCUMULATION OF CYCLIC AMP IN THE RABBIT CEREBRAL CORTEX

1972 • 44 citations

The effect of norepinephrine on cyclic AMP levels in discrete regions of the developing rabbit brain

1971 • 43 citations

Neuroendocrine control of the cyclic AMP system of brain and pineal gland.

1972 • 43 citations

The response of human cerebrum adenyl cyclase to biogenic amines

1971 • 43 citations

Cyclic AMP-mediated adrenergic synapses to cerebellar Purkinje cells.

1972 • 43 citations

Effect of membrane depolarization and biogenic amines on the formation of cyclic AMP in incubated brain slices.

1970 • 43 citations

Synthesis and biological activity of several 6-substituted 9-β-D-ribofuranosylpurine 3',5'-cyclic phosphates

1972 • 42 citations

Adenyl cyclase, cyclic nucleotide phosphodiesterase and axoplasmic flow

1971 • 42 citations

3′:5′‐Cyclic Nucleotide Phosphodiesterases in Rat Tissues

1972 • 41 citations

Cyclic Adenosine Monophosphate and Norepinephrine: Effect on Purkinje Cells in Rat Cerebellar Cortex

1971 • 41 citations

Urinary Excretion of Cyclic Amp and Manic-Depressive Psychosis

1972 • 39 citations

Catecholamine-sensitive adenyl cyclase in cell-free preparations from rat cerebral cortex

1971 • 39 citations

A role of cyclic nucleotides in brain metabolism.

1970 • 38 citations

Purification and properties of cyclic AMP phosphodiesterase from rat brain

1972 • 38 citations

Stimulation of adenosine 3′,5′-monophosphate-dependent and guanosine 3′,5′-monophosphate-dependent protein kinases by some analogs of adenosine 3′,5′-monophosphate

1970 • 38 citations

Adenyl cyclase, phosphodiesterase and cyclic AMP dependent protein kinase of malignant glial cells in culture

1971 • 38 citations

Stimulated formation of adenosine 3′,5′-monophosphate by desipramine in brain slices

1971 • 37 citations

On the development and properties of the brain adenyl cyclase system.

1970 • 36 citations

Psychopharmacological agents and the cyclic AMP system of rat brain.

1972 • 35 citations

Similarities and differences in the norepinephrine-and sodium fluoride-sensitive adenyl cyclase system.

1969 • 34 citations

Cyclic 3′,5′-nucleotide phosphodiesterase in nerve endings of developing rat brain

1971 • 34 citations

THE EFFECT OF NEONATAL THYROIDECTOMY ON THE DEVELOPMENT OF THE ADENOSINE 3′,5′‐MONOPHOSPHATE SYSTEM IN THE RAT BRAIN

1972 • 34 citations

Cyclic AMP formation in human brain: An stimulation by neurotransmitters

1971 • 31 citations

Cyclic AMP and transmission at the neuromuscular junction.

1970 • 30 citations

Measurement of Adenosine 3’, 5’-Monophosphate (Cyclic AMP) in Brain

1970 • 30 citations

Regulation of cyclic AMP levels in brain tissue.

1972 • 29 citations

Changes in cyclic 3′,5′-adenosine monophosphate-dependent protein kinase levels in brain development

1971 • 29 citations

ACCUMULATION OF ADENOSINE 3′,5′‐MONOPHOSPHATE IN BRAIN SLICES: INTERACTION OF LOCAL ANAESTHETICS AND DEPOLARIZING AGENTS

1973 • 28 citations

Dynamic aspects of neurohormonal control of cyclic 3',5'-AMP synthesis in brain.

1970 • 28 citations

Cyclic 3′,5′-nucleotide phosphodiesterase of fish (Salmo gairdnerii) brain

1969 • 26 citations

Cyclic AMP-dependent protein kinases from skeletal muscle and liver.

1972 • 25 citations

Regulation of brain phosphodiesterase activity: Ca++ plus Mg++ -dependent phosphodiesterase and its activating factor from rat brain.

1972 • 25 citations

Localization of adenosine 3′,5′‐monophosphate‐dependent protein kinase in brain

1971 • 25 citations

Protein-bound phosphorylserine in acid hydrolysates of brain tissue. The determination of [32P]phosphorylserine by ion-exchange chromatography and electrophoresis

1971 • 25 citations

Neurohormones on Brain Adenyl Cyclase Activity in vivo

1971 • 25 citations

A Cyclic AMP-Dependent Protein Kinase of the Bovine Pineal Gland

1971 • 25 citations

THE EFFECT OF PERIODIC CONVULSIONS INDUCED BY 1,1‐DIMETHYLHYDRAZINE ON THE GLYCOGEN OF RAT BRAIN

1965 • 25 citations

STUDIES ON THE FORMATION AND METABOLISM OF CYCLIC AMP IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM*

1971 • 24 citations

The activation and inhibition of adenyl cyclase from the brain of the madagascar cockroach (gromphadorhina portentosa)

1972 • 23 citations

URINARY CYCLIC A.M.P. IN AFFECTIVE ILLNESS

1970 • 22 citations

Cytochemical demonstration and localization of adenyl cyclase in skeletal and cardiac muscle.

1972 • 22 citations

16 Nucleoside Cyclic Phosphate Diesterases

1971 • 20 citations

Regulation of cyclic AMP metabolism in cultured cells of the nervous system.

1972 • 19 citations

Distribution of catecholamines and their metabolites in rabbit brain

1964 • 18 citations

The receptor protein for cyclic AMP in the control of glycogenolysis.

1970 • 18 citations

The role of cyclic AMP in visual excitation.

1972 • 17 citations

STUDIES ON THE FUNCTIONAL ROLE OF ADENOSINE 3', 5'-MONOPHOSPHATE, HISTAMINE AND PROSTAGLANDIN E1 IN THE CENTRAL NERVOUS SYSTEM

1971 • 17 citations

The effect of cyclic N-2-O-dibutyryl-adenosine-3′, 5′-monophosphate on neuromuscular transmission and concentration of glycogen in the isolated phrenic nerve-diaphragm preparation of the rat

1972 • 16 citations

Possible cyclic AMP-mediated adrenergic synapses to rat cerebellar Purkinje cells: combined structural, physiological, and pharmacological analyses.

1970 • 15 citations

A study of the bioloical activity and resistance to phosphodiesterase of some derivatives and analogues of cyclic AMP.

1972 • 14 citations

Adenosine 3′,5′-cyclic monophosphate derivatives II. Biological activity of some 8-substituted analogs

1971 • 14 citations

Effect of tranquilizers and antidepressants on glycogen phosphorylase of rat brain

1971 • 13 citations

Inhibition of cyclic 3′,5′-adenosine monophosphate phosphodiesterase by substituted imidazopyrazines

1971 • 12 citations

The effects of propranolol and electrical stimulation on the cyclic 3',5'-AMP content of isolated cerebral tissue

1972 • 10 citations

Cyclic nucleotide phosphodiesterase activity in man, monkey, and rat

1971 • 9 citations

Cyclic AMP in the rat brain: microwave irradiation as a means of tissue fixation.

1972 • 9 citations

Cyclic AMP and nerve function.

1970 • 8 citations

Neural and hormonal regulation of pineal adenyl cyclase activity.

1970 • 7 citations

The effect of putative transmitters and other agents on phosphoprotein turnover in respiring slices of guinea-pig cerebral cortex

1972 • 7 citations

Monitoring Human Birth Defects and Mutations to Detect Environmental Effects

1971 • 6 citations

Adenosine 3′:5′-cyclic monophosphate and adenylate cyclase in subcellular fractions of rat brain

1972 • 5 citations

A study of glycogenolysis in the adult cat brain using a rapid sampling technique

1971 • 4 citations

Deleted Work

1955 • 0 citations