Implication of cAMP during porcine sperm capacitation and protein tyrosine phosphorylation

Fertilizing Capacity of Spermatozoa deposited into the Fallopian Tubes

1951 • 1,451 citations

Capacitation of mouse spermatozoa: I. Correlation between the capacitation state and protein tyrosine phosphorylation

1995 • 950 citations

Observations on the Penetration of the Sperm into the Mammalian Egg

1951 • 907 citations

Capacitation of mouse spermatozoa: II. Protein tyrosine phosphorylation and capacitation are regulated by a cAMP-dependent pathway

1995 • 796 citations

Regulation of Protein Phosphorylation during Sperm Capacitation1

1998 • 486 citations

Sodium bicarbonate in seminal plasma stimulates the motility of mammalian spermatozoa through direct activation of adenylate cyclase.

1985 • 397 citations

Cyclic Adenosine 3′,5′monophosphate-Dependent Regulation of Protein Tyrosine Phosphorylation in Relation to Human Sperm Capacitation and Motility1

1996 • 396 citations

Cyclic Adenosine 3′,5′ Monophosphate, Calcium and Protein Phosphorylation in Flagellar Motility

1983 • 391 citations

Regulation of Protein Tyrosine Phosphorylation during Bovine Sperm Capacitation by a Cyclic Adenosine 3',5'-Monophosphate-Dependent Pathway1

1997 • 388 citations

Regulation of Protein Tyrosine Phosphorylation in Human Sperm by a Calcium/Calmodulin-Dependent Mechanism: Identification of A Kinase Anchor Proteins as Major Substrates for Tyrosine Phosphorylation

1996 • 319 citations

Timing of fertilization in mammals: sperm cholesterol/phospholipid ratio as a determinant of the capacitation interval.

1981 • 310 citations

The capacitating agent bicarbonate induces protein kinase A-dependent changes in phospholipid transbilayer behavior in the sperm plasma membrane

2000 • 299 citations

Regulation of Protein Phosphorylation and Motility of Sperm by Cyclic Adenosine Monophosphate and Calcium

1982 • 253 citations

Bicarbonate/CO2, an effector of capacitation, induces a rapid and reversible change in the lipid architecture of boar sperm plasma membranes

1996 • 249 citations

Roles of Bicarbonate, cAMP, and Protein Tyrosine Phosphorylation on Capacitation and the Spontaneous Acrosome Reaction of Hamster Sperm1

1999 • 212 citations

Capacitation Is Associated with Tyrosine Phosphorylation and Tyrosine Kinase-Like Activity of Pig Sperm Proteins1

2001 • 207 citations

Identification of sterol acceptors that stimulate cholesterol efflux from human spermatozoa during in vitro capacitation

1988 • 171 citations

Flow cytometric studies of bicarbonate‐mediated Ca²⁺ influx in boar sperm populations

1993 • 171 citations

Extracellular Calcium Negatively Modulates Tyrosine Phosphorylation and Tyrosine Kinase Activity during Capacitation of Human Spermatozoa1

1996 • 165 citations

Regulation of sperm flagellar motility by calcium and cAMP‐dependent phosphorylation

1987 • 160 citations

Capacitation Induces Tyrosine Phosphorylation of Proteins in the Boar Sperm Plasma Membrane

1999 • 160 citations

Rapid PKA‐catalysed phosphorylation of boar sperm proteins induced by the capacitating agent bicarbonate

2004 • 135 citations

Regulation of protein tyrosine phosphorylation in boar sperm through a cAMP-dependent pathway

1998 • 134 citations

Changes in sperm plasma membrane lipid diffusibility after hyperactivation during in vitro capacitation in the mouse.

1986 • 130 citations

Differences in the Role of Cyclic Adenosine 3′,5′-Monophosphate during Capacitation of Bovine Sperm by Heparin or Oviduct Fluid1

1994 • 126 citations

cAMP-dependent protein kinase control of plasma membrane lipid architecture in boar sperm

2000 • 118 citations

A requirement of bicarbonate for Ca2+-induced elevations of cyclic AMP in guinea pig spermatozoa.

1982 • 116 citations

Regulation of Guinea Pig Sperm Adenylate Cyclase by Calcium1

1979 • 111 citations

The Cyclic GMP‐Specific Phosphodiesterase Inhibitor, Sildenafil, Stimulates Human Sperm Motility and Capacitation but Not Acrosome Reaction

2000 • 103 citations

Porcine Sperm Capacitation and Tyrosine Kinase Activity Are Dependent on Bicarbonate and Calcium but Protein Tyrosine Phosphorylation Is Only Associated with Calcium1

2003 • 102 citations

Dibutyryl cyclic AMP decreases capacitation time in vitro in mouse spermatozoa

1981 • 101 citations

Stimulation of partially purified adenylate cyclase from bull sperm by bicarbonate

1987 • 100 citations

Accelerated mouse sperm penetration in vitro in the presence of caffeine

1979 • 78 citations

Protein Tyrosine Phosphorylation Is Associated with Capacitation of Human Sperm In Vitro but Is Not Sufficient for Its Completion1

1997 • 72 citations

Capacitation-associated changes in protein tyrosine phosphorylation, hyperactivation and acrosome reaction in hamster spermatozoa

2001 • 64 citations

Heparin-Induced Capacitation but not Intracellular Alkalinization of Bovine Sperm is Inhibited by Rp-Adenosine-3′,5′-Cyclic Monophosphorothioate1

1994 • 55 citations

Cyclic nucleotide metabolism in mouse epididymal spermatozoa during capacitation in vitro

1984 • 51 citations

The Importance of Calcium in the Appearance of p32, a Boar Sperm Tyrosine Phosphoprotein, During In Vitro Capacitation

2003 • 49 citations

Identification of capacitation-associated phosphoproteins in porcine sperm electroporated with ATP-?-32P

1999 • 45 citations

Adenylate cyclase activity of mouse sperm during capacitation in vitro: effect of calcium and a GTP analogue

1986 • 43 citations

Responses of monkey epididymal sperm of different maturational status to second messengers mediating protein tyrosine phosphorylation, acrosome reaction, and motility

1999 • 24 citations

Forskolin stimulates porcine sperm capacitation by increasing calcium uptake

1993 • 22 citations

Biochemical characterization of the boar sperm 42 kilodalton protein tyrosine kinase: Its potential for tyrosine as well as serine phosphorylation towards microtubule‐associated protein 2 and histone H 2B

1994 • 22 citations

Changes in lipid diffusibility in the hamster sperm head plasma membrane during capacitation in vivo and in vitro

1998 • 19 citations