The Involvement of Copper Transporter in Lead-induced Oxidative Stress in Astroglia

Intellectual Impairment in Children with Blood Lead Concentrations below 10 μg per Deciliter

2003 • 2,053 citations

Deficits in Psychologic and Classroom Performance of Children with Elevated Dentine Lead Levels

1979 • 1,587 citations

Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper–transporting ATPase

1993 • 1,395 citations

Copper biochemistry and molecular biology

1996 • 1,171 citations

Bone Lead Levels and Delinquent Behavior

1996 • 628 citations

In Situ Oxidative Catalysis by Neurofibrillary Tangles and Senile Plaques in Alzheimer’s Disease

2000 • 526 citations

A site-specific mechanism for free radical induced biological damage: The essential role of redox-active transition metals

1988 • 505 citations

Occupational exposures to metals as risk factors for Parkinson's disease

1997 • 449 citations

The Endoplasmic Reticulum Stress-Responsive Protein GRP78 Protects Neurons Against Excitotoxicity and Apoptosis: Suppression of Oxidative Stress and Stabilization of Calcium Homeostasis

1999 • 440 citations

Occupational exposure to manganese, copper, lead, iron, mercury and zinc and the risk of Parkinson's disease.

1999 • 422 citations

A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-kappa B.

1995 • 402 citations

Molecular mechanisms of lead neurotoxicity.

1999 • 301 citations

Blood Lead Concentration and Delayed Puberty in Girls

2003 • 281 citations

N-terminal Domains of Human Copper-transporting Adenosine Triphosphatases (the Wilson's and Menkes Disease Proteins) Bind Copper Selectively in Vivo and in Vitro with Stoichiometry of One Copper Per Metal-binding Repeat

1997 • 237 citations

The Alzheimer's Disease Amyloid Precursor Protein Modulates Copper-Induced Toxicity and Oxidative Stress in Primary Neuronal Cultures

1999 • 222 citations

Disorders of copper transport

1995 • 195 citations

In vivo indices of oxidative stress in lead-exposed C57BL/6 mice are reduced by treatment with meso-2,3-Dimercaptosuccinic Acid or N-acetylcysteine

1996 • 170 citations

Astroglia as Metal Depots: Molecular Mechanisms for Metal Accumulation, Storage and Release

2001 • 160 citations

Declining Blood Lead Levels and Changes in Cognitive Function During Childhood

1998 • 150 citations

Copper Transport: An Overview

1991 • 146 citations

Permeability of the blood-brain barrier to lead.

1993 • 129 citations

Maturation of resistance to lead encephalopathy: cellular and subcellular mechanisms.

1984 • 112 citations

Neuropsychological correlates of low-level lead exposure in school-age children: A prospective study

1993 • 109 citations

Functional analysis and intracellular localization of the human menkes protein (MNK) stably expressed from a cDNA construct in Chinese hamster ovary cells (CHO-K1)

1998 • 89 citations

Differential ability of astroglia and neuronal cells to accumulate lead: dependence on cell type and on degree of differentiation

1999 • 88 citations

Risk of Nervous System Cancer Among Workers Exposed to Lead

1996 • 85 citations

Lead toxicity in neuroglia.

1989 • 84 citations

Lead-induced endoplasmic reticulum (ER) stress responses in the nervous system.

2003 • 79 citations

Lead Targets GRP78, a Molecular Chaperone, in C6 Rat Glioma Cells

2000 • 75 citations

Brain Cancer and Occupational Exposure to Lead

1998 • 71 citations

Peroxidative stress selectively down‐regulates the neuronal stress response activated under conditions of endoplasmic reticulum dysfunction

2001 • 69 citations

Copper transport and kinetics in cultured C6 rat glioma cells

1995 • 65 citations

GRP78 Compartmentalized Redistribution in Pb-treated Glia: Role of GRP78 in Lead-induced Oxidative Stress

2004 • 59 citations

High prevalence of parkinsonism after occupational exposure to lead‐sulfate batteries

1998 • 56 citations

N-Acetylcysteine Exposure on Lead-Induced Lipid Peroxidative Damage and Oxidative Defense System in Brain Regions of Rats

2004 • 56 citations

Induction of 78 kD glucose-regulated protein (GRP78) expression and redox-regulated transcription factor activity by lead and mercury in C6 rat glioma cells

2001 • 55 citations

Effects of lead treatment on intracellular iron and copper concentrations in cultured astroglia

1987 • 44 citations

Interference of Pb with essential brain tissue Cu, Fe, and Zn as main determinant in experimental tetraethyllead encephalopathy

1973 • 43 citations

Differential induction of heme oxygenase and other stress proteins in cultured hippocampal astrocytes and neurons by inorganic lead

2004 • 43 citations

Differential profiles of copper-induced ROS generation in human neuroblastoma and astrocytoma cells

2005 • 42 citations

Low-level lead exposure in cultured astroglia: identification of cellular targets with vital fluorescent probes.

1993 • 41 citations

A Menkes P-type ATPase involved in copper homeostasis in the central nervous system of the rat

1997 • 33 citations

Low level lead neurotoxicity in a pregnant guinea pigs model: neuroglial enzyme activities and brain trace metal concentrations

1989 • 31 citations

Lead and cancer -- association or causation?

1997 • 31 citations

The relationship between parkinson syndrome and vascular siderosis: An electron microprobe study

1977 • 21 citations

Zinc, copper and lead levels in blood, spinal cord and different parts of the brain in rabbit: effect of zinc-intoxication.

1982 • 9 citations