Pre-clinical screening of drugs using the mdx mouse

Complete cloning of the duchenne muscular dystrophy (DMD) cDNA and preliminary genomic organization of the DMD gene in normal and affected individuals

1987 • 2,353 citations

Muscle biopsy: A modern approach

1975 • 1,405 citations

Muscle Biopsy: A Modern Approach

1974 • 1,346 citations

The Molecular Basis of Muscular Dystrophy in the mdx Mouse: a Point Mutation

1989 • 1,171 citations

Randomized, Double-Blind Six-Month Trial of Prednisone in Duchenne's Muscular Dystrophy

1989 • 505 citations

Duchenne dystrophy

1975 • 438 citations

Disruptions of muscle fiber plasma membranes. Role in exercise-induced damage.

1992 • 431 citations

THE mdx MOUSE SKELETAL MUSCLE MYOPATHY: I. A HISTOLOGICAL, MORPHOMETRIC AND BIOCHEMICAL INVESTIGATION

1988 • 343 citations

Skeletal muscle pathology in X chromosome-linked muscular dystrophy (mdx) mouse

1986 • 322 citations

Increased susceptibility of EDL muscles from mdx mice to damage induced by contractions with stretch

1993 • 319 citations

Prednisone in Duchenne Dystrophy

1991 • 270 citations

PREDNISONE IN DUCHENNE MUSCULAR DYSTROPHY

1974 • 201 citations

Duchenne dystrophy

1993 • 199 citations

Clinical Investigation of Duchenne Muscular Dystrophy

1987 • 153 citations

Prednisone Treatment in Duchenne Muscular Dystrophy

1987 • 147 citations

A role for collagen in the pathogenesis of muscular dystrophy?

1980 • 130 citations

Negative immunostaining of Duchenne muscular dystrophy(DMD) and mdx muscle surface membrane with antibody against synthetic peptide fragment predicted from DMD cDNA.

1988 • 127 citations

A Comparison of Daily and Alternate-Day Prednisone Therapy in the Treatment of Duchenne Muscular Dystrophy

1991 • 117 citations

A role for mast cells in the progression of Duchenne muscular dystrophy?

1994 • 108 citations

Segmental fibre breakdown and defects of the plasmalemma in diseased human muscles

1975 • 101 citations

Elevated basic fibroblast growth factor in the serum of patients with Duchenne muscular dystrophy

1994 • 84 citations

Assisted Reproduction and Selective Reduction of Pregnancy

1987 • 78 citations

Prednisone in Duchenne dystrophy

1991 • 77 citations

Insulin-like growth factor I accelerates protein synthesis in skeletal muscle during sepsis

1995 • 74 citations

Effects of contractile activity on muscle damage in the dystrophin-deficient mdx mouse

1991 • 60 citations

Strength and endurance in the therapeutic evaluation of prednisolone-treated MDX mice.

1993 • 60 citations

Recruitment of mast cells to muscle after mild damage

1996 • 58 citations

Human Muscular Dystrophy as an Aberration of the Connective Tissue

1959 • 56 citations

Animal modes of Duchenne and Becker muscular dystrophy

1989 • 52 citations

Considerations About a Possible Role Played by Connective Tissue Proliferation and Vascular Disturbances in the Pathogenesis of Progressive Muscular Dystrophy

1968 • 45 citations

Regeneration of human muscle. A morphologic and histochemical study of normal and dystrophic muscle after injury.

1972 • 30 citations

Mast cells in neuromuscular diseases

1990 • 21 citations

MDX Mouse as Therapeutic Model System: Development and Implementation of Phenotypic Monitoring

1990 • 14 citations

Enhanced sensitivity of mdx mice to intramuscular injection of compound 48/80.

1994 • 8 citations

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