Anatomy of the renin‐angiotensin system in the normal and pathological kidney

Mechanisms regulating renin release

1976 • 886 citations

Local regulation of adrenergic neurotransmission.

1977 • 645 citations

Angiotensin-Converting Enzyme: Vascular Endothelial Localization

1976 • 644 citations

The plasma membrane sodium-hydrogen exchanger and its role in physiological and pathophysiological processes.

1985 • 506 citations

Distribution of epithelial membrane antigen in normal and neoplastic tissues and its value in diagnostic tumor pathology

1981 • 404 citations

Hypertension due to a renin-secreting renal tumour

1967 • 353 citations

Cloning and sequence analysis of cDNA for human renin precursor.

1983 • 266 citations

Facilitation of adrenergic transmission by locally generated angiotensin II in rat mesenteric arteries.

1976 • 226 citations

Contribution of the renin-angiotensin system to the control of intrarenal hemodynamics

1984 • 216 citations

Complete amino acid sequence and maturation of the mouse submaxillary gland renin precursor

1982 • 190 citations

Renin synthesis by canine aortic smooth muscle cells in culture

1982 • 175 citations

The innervation of the juxtaglomerular apparatus and surrounding tubules: A quantitative analysis by serial section electron microscopy

1973 • 173 citations

Cancer of the kidney—etiology, epidemiology, and pathology

1973 • 161 citations

Evidence for renal glomerular receptors for angiotensin II

1974 • 148 citations

Primary reninism. Hypertension, hyperreninemia, and secondary aldosteronism due to renin-producing juxtaglomerular cell tumors

1972 • 144 citations

Angiotensin II in arterial and renal venous plasma and renal lymph in the dog

1971 • 136 citations

Analysis of angiotensin‐stimulated sodium transport in cultured smooth muscle cells from rat aorta

1983 • 133 citations

Renin Levels in Nephroblastoma (Wilms' Tumour): Report of a Renin Secreting Tumour

1970 • 124 citations

Local generation of angiotensin II as a mechanism of regulation of peripheral vascular tone in the rat.

1984 • 123 citations

A HITHERTO UNREPORTED VASCULAR TUMOR OF THE KIDNEY: A PROPOSAL OF ‘JUXTAGLOMERULAR CELL TUMOR’

1968 • 120 citations

Renin and angiotensin‐like activity in renal lymph

1962 • 120 citations

Renin expression by vascular endothelial cells in culture.

1985 • 118 citations

Glutamyl Peptidases in Rat and Guinea Pig Kidney Slices

1961 • 116 citations

�ber einen merkw�rdigen Abschnitt der Vasa afferentia in der M�useniere

1925 • 110 citations

BIG RENIN: A POSSIBLE PROHORMONE IN KIDNEY AND PLASMA OF A PATIENT WITH WILMS' TUMOR¹

1974 • 108 citations

A method for staining the pepsinogen granules in gastric glands

1936 • 106 citations

Renin biosynthesis by human tumoral juxtaglomerular cells. Evidences for a renin precursor.

1984 • 102 citations

Angiotensin II Binding Sites on Isolated Rat Renal Brush Border Membranes*

1982 • 100 citations

Immunocytochemical localization of angiotensinogen in rat liver and kidney

1983 • 100 citations

Sympathetic Innervation of the Juxtaglomerular Cells of the Kidney

1968 • 99 citations

The development and ultrastructure of the juxtaglomerular cell granule

1966 • 99 citations

Metaplasia of smooth muscle cells into juxtaglomerular cells in the juxtaglomerular apparatus, arteries, and arterioles of the ischemic (endocrine) kidney. An ultrastructural-cytochemical and autoradiographic study.

1977 • 97 citations

Renin-Secreting Renal Neoplasm and Hypertension with Hypokalemia

1971 • 96 citations

Immunocytochemical localization of renin in mouse kidney

1979 • 93 citations

The granulated peripolar epithelial cell: a potential secretory component of the renal juxtaglomerular complex

1979 • 92 citations

Role of renin and aldosterone in hypertension due to a renin-secreting tumor

1973 • 92 citations

The assay of renin in single glomeruli in the normal rabbit and the appearance of the juxtaglomerular apparatus

1965 • 91 citations

Evidence for the Local Occurrence of Angiotensin II in Rat Kidney and its Modulation by Dietary Sodium Intake and Converting Enzyme Blockade

1979 • 87 citations

Renin-Secreting Wilms' Tumor with Severe Hypertension

1973 • 84 citations

Granulocyte-angiotensin system. Identification of angiotensinogen as the plasma protein substrate of leukocyte cathepsin G

1984 • 83 citations

The distribution of epithelial membrane antigen in the kidney and its tumours

1985 • 83 citations

Alveolar soft-part sarcoma—A malignant angioreninoma

1982 • 83 citations

Enzyme activities of the single juxtaglomerular apparatus in the rat kidney

1972 • 80 citations

Alveolar soft-part sarcoma

1983 • 75 citations

Converting-enzyme in the choroid plexus, brain, and kidney: Immunocytochemical and biochemical studies in rats

1981 • 73 citations

Ultrastructural changes associated with renin secretion from the juxtaglomerular apparatus of mice

1984 • 72 citations

Renin-Secreting Clear Cell Carcinoma of the Kidney

1975 • 71 citations

Use of a specific antiserum for renin detection in human kidney.

1980 • 69 citations

Characteristics and Regulation of Angiotensin II Receptors in Pituitary, Circumventricular Organs and Kidney

1983 • 68 citations

Comparative Endocrinology of Renin and Angiotensin

1980 • 67 citations

Structure of the Juxtaglomerular Apparatus

1980 • 66 citations

THE ASSOCIATION OF ADENO-MYO-SARCOMA OF THE KIDNEY (WILMS TUMOR) WITH ARTERIAL HYPERTENSION

1938 • 65 citations

The distribution of renin in the different segments of the renal arterial tree

1981 • 62 citations

Juxtaglomerular cell tumor of the kidney

1984 • 61 citations

Coexistence of renin and angiotensin II in epitheloid cell secretory granules of rat kidney

1984 • 60 citations

Angiotensin II: evidence for its role as an intrarenal hormone.

1982 • 60 citations

Studies on the juxtaglomerular apparatus

1977 • 60 citations

Renin immunocytochemistry of the differentiating juxtaglomerular apparatus

1981 • 59 citations

Biology and Pathology of the Vessel Wall

1984 • 55 citations

Ultrastructural immunocytochemical localization of renin and angiotensin II in the juxtaglomerular cells of the ischemic kidney in experimental renal hypertension.

1984 • 52 citations

Identification of an angiotensin receptor in rabbit renomedullary interstitial cells in tissue culture. Correlation with prostaglandin biosynthesis.

1980 • 51 citations

AUTONOMIC INNERVATION AND TRANSMISSION

1979 • 50 citations

Histological changes in the ischemic kidney: With special reference to the juxtaglomerular apparatus.

1940 • 50 citations

Juxtaglomerular body tumor: A rare occult but curable cause of lethal hypertension

1974 • 50 citations

Renin secretion at the individual nephron level

1975 • 49 citations

Properties of Angiotensin II Receptors of Isolated Rat Glomeruli: Factors Influencing Binding Affinity and Comparative Binding of Angiotensin Analogs*

1980 • 49 citations

The localization of converting enzyme in kidney vessels of the rat

1982 • 48 citations

Hypertension Associated with a Renin-Secreting Adenocarcinoma of the Pancreas

1982 • 48 citations

Polydipsia, polyuria, and hypertension associated with renin-secreting Wilms tumor

1978 • 47 citations

Renin content in superficial and deep glomeruli of normal and salt-loaded rats

1974 • 46 citations

Renin in renal cell carcinoma--an immunocytochemical study using an antibody to pure human renin.

1984 • 46 citations

Renin in the human kidney

1981 • 44 citations

Renin producing Wilms' tumor

1981 • 44 citations

Renin storage and cell differentiation in juxtaglomerular cell tumors: An immunohistochemical and ultrastructural study of three cases

1984 • 41 citations

Immunoreactive renin and angiotensin II in the afferent glomerular arterioles of rats with hypertension due to unilateral renal artery constriction

1982 • 41 citations

High plasma renin activity in an oat cell carcinoma: A renin-secreting carcinoma?

1970 • 41 citations

The effect of preoperative roentgen-ray therapy on arterial hypertension in embryoma (kidney)

1949 • 41 citations

The assay of renin in single glomeruli and the appearance of the juxtaglomerular apparatus in the rabbit following renal artery constriction.

1966 • 41 citations

Abnormalities of renin-containing cells in human glomerular and vascular renal diseases

1983 • 40 citations

Immunohistochemical characterization of renin-containing cells in the human juxtaglomerular apparatus during embryonal and fetal development.

1981 • 39 citations

The immunocytochemical demonstration of renin in a juxtaglomerular cell tumour by light and electron microscopy

1983 • 39 citations

Structure of a juxtaglomerular cell tumor: the presence of a neural component: a light and electron microscopic study.

1977 • 38 citations

Angiotensin II in epitheloid (Renin containing) cells of rat kidney

1981 • 37 citations

Renin synthesis, storage, and release in the rat: A morphological and biochemical study

1977 • 36 citations

Ultrastructural morphology of granule release from juxtaglomerular myoepithelioid and peripolar cells.

1982 • 36 citations

A juxtaglomerular cell tumour: light and electron microscopic studies of a renin-secreting kidney tumour containing both juxtaglomerular cells and mast cells

1972 • 35 citations

Immunocytochemical localization of renin in juxtaglomerular cells.

1985 • 35 citations

The granular peripolar cell of the human glomerulus: a new component of the juxtaglomerular apparatus?

1985 • 34 citations

Renin-secreting tumor associated with hypertension

1974 • 34 citations

Autoantibodies and Vascular Events in Essential Hypertension: A Five/year Longitudinal Study

1984 • 32 citations

Malignant hypertension with hypokalemia in a patient with renin-producing pulmonary carcinoma.

1975 • 31 citations

A Renal Carcinoma Secreting Inactive Renin

1978 • 30 citations

Ultrastructural studies on the secretory process in the epithelioid cells of the juxtaglomerular apparatus

1976 • 30 citations

Potential effects of renin activation on the regulation of renin production

1984 • 29 citations

Immunocytochemical localisation of renin in nephroblastoma.

1984 • 28 citations

Adenocarcinoma of the Kidney and Hypertension: Report of 2 Cases with Special Emphasis on Renin

1977 • 28 citations

Congenital mesoblastic nephroma presenting with primary reninism

1979 • 28 citations

Biochemical and Immunological Characterization of Ectopic Tumoral Renin

1982 • 27 citations

DETECTION OF RENIN mRNA IN MOUSE KIDNEY AND SUBMANDIBULAR GLAND BY HYBRIDIZATION WITH RENIN cDNA*

1983 • 26 citations

Renin localization in segmental renal hypoplasia

1981 • 25 citations

Delayed diagnosis of juxtaglomerular cell tumor hypertension.

1982 • 24 citations

Renin Gene Expression in Vessels of the Ovine Renal Cortex

1985 • 22 citations

Human Renin Granules: Ultrastructural Aspects

1983 • 21 citations

THE CONVERSION OF ANGIOTENSIN I TO ANGIOTENSIN II BY RABBIT GLOMERULI

1972 • 21 citations

An ultrastructural and immunocytochemical study of a renal carcinoma secreting inactive renin.

1983 • 20 citations

Functional Interaction between Angiotensin and Sympathetic Reflexes in Cats

1982 • 20 citations

Epithelial liver hamartoma, systemic arterial hypertension and renin hypersecretion

1975 • 19 citations

Fine morphology of human juxtaglomerular cells in patients with benign essential hypertension.

1966 • 19 citations

Juxtaglomerular cells in renal angiomyolipoma Ultrastructural observation

1984 • 18 citations

A case of ectopic renin-secreting orbital hemangiopericytoma associated with juvenile hypertension and hypokalemia.

1979 • 18 citations

Immunohistochemical localization of tonin in rat salivary glands and kidney

1982 • 17 citations

REGULATION OF THE PERMEABILITY TO WATER IN TOAD URINARY BLADDER: THE EFFECT OF COPPER

1972 • 16 citations

A Micropuncture Study of Glomerular Filtration and Tubular Reabsorption of Endogenous Renin in the Rat

1978 • 16 citations

Studies on the juxtaglomerular apparatus

1974 • 16 citations

Angiotensin II receptors in chromatin.

1984 • 15 citations

Secondary Forms of Hypertension

2010 • 14 citations

Immunohistochemistry of the Renin-Angiotensin-System in the kidney

1983 • 14 citations

Histochemistry of angiotensinase A in the glomerulus and the juxtaglomerular apparatus.

1982 • 14 citations

Release of active and inactive renin from hog renal cortical slices in vitro

1984 • 13 citations

Direct Radioimmunoassay and Immunocytochemical Localization of Renin in Human Kidneys

1979 • 12 citations

JUXTAGLOMERULAR CELL TUMOR

1983 • 12 citations

Angiotensin-like activity in resistance vessels

1983 • 11 citations

New Morphological Evidence for the Synthesis and Storage of Renin in the Human Kidney: An Ultrastructural Immunocytochemical Study

1984 • 11 citations

The juxtaglomerular apparatus in malignant hypertension of man

1976 • 10 citations

Inactive Renin in Peritoneal Fluid???An Independent System or a Transport Form of Circulating Renin?

1984 • 10 citations

Granular cells in the juxtaglomerular apparatus in perinatal rats

1975 • 8 citations

(5)THE RENIN-ANGIOTENSIN SYSTEM

1974 • 8 citations

Changes in Blood Pressure in Relation to Vascular and Plasma Renin after Renin Injection in Rats

1982 • 8 citations

Angiotensin II immunoreactivity coexisting with renin in the human juxtaglomerular epithelioid cells.

1982 • 8 citations

Immunohistochemistry of Renin in Human Diseased Kidney

1983 • 6 citations

Binding of Human Renin to Plasma Proteins and Comparison with Plasma Active and Inactive Renin

1985 • 5 citations

The Renin—Angiotensin Converting Enzyme Cascade: Renin and blood pressure

1984 • 5 citations

Human antirenin antibody: a new tool for studying the renin-angiotensin system.

1983 • 4 citations