Fate of DNA lesions that elicit sister-chromatid exchanges

New Giemsa method for the differential staining of sister chromatids

1974 • 3,198 citations

A Manyfold Increase in Sister Chromatid Exchanges in Bloom's Syndrome Lymphocytes

1974 • 934 citations

Sister Chromatid Exchange

1983 • 387 citations

Sister chromatid exchanges induced in chinese hamster cells by UV irradiation of different stages of the cell cycle: The necessity for cells to pass through S

1974 • 312 citations

A replication model for sister-chromatid exchange

1980 • 289 citations

Simple differential Giemsa staining of sister chromatids after treatment with photosensitive dyes and exposure to light and the mechanism of staining

1975 • 285 citations

A retarded rate of DNA chain growth in Bloom's syndrome.

1975 • 210 citations

Chemical carcinogenesis in the nervous system. Preferential accumulation of O6-methylguanine in rat brain deoxyribonucleic acid during repetitive administration of N-methyl-N-nitrosourea

1975 • 206 citations

Localization of Sister Chromatid Exchanges in Human Chromosomes

1974 • 205 citations

Effects of inhibitors of DNA synthesis on spontaneous and ultraviolet light-induced sister-chromatid exchanges in Chinese hamster cells

1980 • 179 citations

Molecular Mechanisms in Genetic Recombination

1982 • 176 citations

Mechanisms for sister chromatid exchanges and their relation to the production of chromosomal aberrations

1977 • 141 citations

Sister chromatid exchange studies for monitoring DNA damage and repair capacity after cytostatics in vitro and in lymphocytes of leukaemic patients under cytostatic therapy

1978 • 140 citations

On the mechanism of genetic recombination: electron microscopic observation of recombination intermediates.

1976 • 135 citations

DNA crosslinking, sister-chromatid exchange and specific-locus mutations

1979 • 134 citations

Kinetics of branch migration in double-stranded DNA.

1976 • 133 citations

Bromodeoxyuridine tablet methodology for in vivo

1978 • 111 citations

Replication bypass model of sister chromatid exchanges and implications for Bloom's Syndrome and Fanconi's anemia

1977 • 103 citations

Kinetics of cyclophosphamide biotransformation in vivo.

1980 • 97 citations

Distribution of sister chromatid exchanges in the euchromatin and heterochromatin of the Indian muntjac

1975 • 95 citations

Induction of long-lived chromosome damage, as manifested by sister-chromatid exchange, in lymphocytes of animals exposed to mitomycin-C

1978 • 88 citations

Characterization of sister chromatid exchange induction by 8-methoxypsoralen plus near UV light

1978 • 80 citations

Factors influencing the frequency of mitomycin C-induced sister-chromatid exchanges in 5-bromodeoxyuridine-substituted human lymphocytes in culture

1978 • 72 citations

The effect of sera on sister chromatid exchanges in vitro

1977 • 61 citations

Factors influencing sister-chromatid exchange rate in cultured human lymphocytes

1981 • 58 citations

Induction and persistence of SCE-inducing damage in human lymphocytes exposed to vinyl acetate and acetaldehyde in vitro

1985 • 58 citations

Cell-Cycle-Specific Chromosome Damage Following Treatment of Cultured Chinese Hamster Cells With 4′-[(9-Acridinyl-amino] methanesulphon-m-anisidide-HCl2

1978 • 56 citations

Analysis of the frequency of sister chromatid exchange in different regions of chromosomes of the kangaroo rat (Dipodomys ordii)

1976 • 50 citations

Induction and rapid repair of sister-chromatid exchanges in multiple murine tissues in vivo by diepoxybutane

1983 • 45 citations

Detection by density equilibrium centrifugation of recombinant-like DNA molecules in somatic mammalian cells

1975 • 45 citations

The relationship between the cell time available for repair and the effectiveness of a damaging treatment in provoking the formation of sister-chromatid exchanges

1980 • 43 citations

Enhancement of N-methyl-N'-nitro-N-nitrosoguanidine transformation of Syrian hamster cells by a phorbol diester is independent of sister chromatid exchanges and chromosome aberrations.

1980 • 42 citations

Sister chromatid exchange induced by short‐lived monoadducts produced by the bifunctional agents mitomycin C and 8‐methoxypsoralen

1982 • 42 citations

Analysis in vivo of sister-chromatid exchange in mouse bone-marrow and salivary-gland cells

1980 • 42 citations

Molecular recombination and the repair of DNA double-strand breaks in CHO cells

1979 • 42 citations

The fate of U.V.-induced lesions affecting SCEs, chromosome abberrations and survival of CHO cells arrested by deprivation of arginine

1979 • 41 citations

Relationships between the DNA adducts and the mutations and sister-chromatid exchanges produced in Chinese hamster ovary cells by N-hydroxy-2-aminofluorene, N-hydroxy-N′-acetylbenzidine and 1-nitrosopyrene

1986 • 40 citations

Relationship of Enhanced Survival during Confluent Holding Recovery in Ultraviolet-Irradiated Human and Mouse Cells to Chromosome Aberrations, Sister Chromatid Exchanges, and DNA Repair

1982 • 38 citations

Differential rates of sister chromatid exchanges between euchromatin and heterochromatin

1976 • 38 citations

Induction of sister-chromatid exchanges (SCEs) and chromosomal aberrations by mitomycin C and methyl methanesulfonate in Chinese hamster ovary cells

1983 • 37 citations

Evidence that the replication point is the site of sister chromatid exchange

1980 • 36 citations

Evidence for the formation of hybrid DNA during mitotic recombination in Chinese hamster cells

1976 • 36 citations

Micrococcus luteus UV-endonuclease-sensitive sites and sister-chromatid exchanges in Chinese hamster ovary cells

1979 • 33 citations

Temperature-dependence of sister chromatid exchange: An implication for its mechanism

1980 • 33 citations

Further analysis of the replication bypass model for sister chromatid exchange

1979 • 33 citations

Persistence of ethyl carbamate-induced DNA damage in vivo as indicated by sister chromatid exchange analysis.

1983 • 31 citations

The distribution of mitomycin C-induced sister chromatid exchanges in the euchromatin and heterochromatin of the Indian Muntjac

1977 • 31 citations

Methyl methane-sulphonate (MMS) induced SCEs are reduced by the BrdU used to visualise them

1981 • 30 citations

Relationship between DNA adduct formation and sister chromatid exchange induction by [3H]8-methoxypsoralen in Chinese hamster ovary cells

1980 • 30 citations

DNA repair replication, DNA breaks and sister-chromatid exchange in human cells treated with adriamycin in vitro

1983 • 29 citations

Sister-chromatid exchange induction in Chinese hamster ovary cells by 8-methoxypsoralen and brief pulses of laser light assessment of the relative importance of 8-methoxypsoralen—DNA monoadducts and crosslinks

1981 • 28 citations

A new method for the identification of SCE's per cell cycle in BrdUrd ? Substituted chromosomes

1980 • 27 citations

Implications of somatic recombination and sister chromatid exchange in Bloom's syndrome and cells treated with mitomycin C

1975 • 27 citations

Occurrence in vivo of sister chromatid exchanges at the same locus in successive ceil divisions caused by nonrepairable lesions induced by gamma rays

1988 • 22 citations

Different SCE-inducing effects of HN2 and MMS in early and late G1 in human lymphocytes

1984 • 22 citations

Nature of the mitomycin-C induced lesion causing sister-chromatid e exchange

1981 • 21 citations

Detection of SCE in Rodent Cells Using the Activated Charcoal Bromodeoxyuridine System

1984 • 21 citations

In vivo persistence of sister chromatid exchanges (SCE) induced by gamma rays in mouse bone marrow cells

1984 • 20 citations

Dyskeratosis congenita: Survival, sister-chromatid exchange and repair following treatments with crosslinking agents

1982 • 20 citations

Blocked 5′-termini in the fragments of chromosomal DNA produced in cells exposed to the antitumour drug 4′-[(9-acridinyl)-amino]methanesulphon-m-anisidide (mAMSA)

1983 • 20 citations

A path probability model for sister-chromatid exhanges induced by alkylating agents

1984 • 18 citations

Effect of 5-bromodeoxyuridine substitution on sister chromatid exchange induction by chemicals

1984 • 18 citations

Persistence of DNA lesions and the cytological cancellation of sister chromatid exchanges

1985 • 17 citations

SCE frequencies in rabbit lymphocytes as a function of time after an acute dose of cyclophosphamide

1982 • 17 citations

Analysis of spontaneous sister-chromatid exchanges in vivo by three-way differentiation

1987 • 16 citations

Physical, chemical, and biological factors affecting sister-chromatid exchange induction in human lymphocytes exposed to mitomycin C prior to culture

1981 • 15 citations

Sister-chromatid exchanges in human lymphocytes after a non-S-phase incubation period to allow excision DNA repair-in vitro exposure to N-acetoxy-2-acetylaminofluorene and ethylene oxide

1984 • 15 citations

Persistence of cyclophosphamide-induced damage in bone marrow as indicated by sister chromatid exchange analysis

1985 • 14 citations

Persistence of sister chromatid exchanges and in vitro morphological transformation of Syrian hamster fetal cells by chemical and physical carcinogens

1985 • 12 citations

Effects of caffeine-induced defective DNA replication on SCE and chromosome aberrations produced by alkylating agents

1980 • 12 citations

Effect of post-treatment with aphidicolin — a specific inhibitor of DNA polymerase α — on sister-chromatid exchanges induced by ethyl methanesulfonate

1982 • 11 citations

DNA replication and sister chromatid exchange in 9qh+

1983 • 5 citations

A MODEL FOR POSTREPLICATION REPAIR OF UV DAMAGE IN MAMMALIAN CELLS

1978 • 3 citations