Design, Synthesis, and Evaluation of Chromen-2-ones as Potent and Selective Human Dopamine D4 Antagonists

Prestimulus Effects on Human Startle Reflex in Normals and Schizophrenics

1978 • 1,173 citations

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

1991 • 1,157 citations

Dopamine receptors and the dopamine hypothesis of schizophrenia

1987 • 867 citations

Neuropsychopharmacology

2004 • 652 citations

Dopaminergic stimulation disrupts sensorimotor gating in the rat

1988 • 609 citations

3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine: An Antagonist with High Affinity and Selectivity for the Human Dopamine D₄ Receptor

1996 • 257 citations

Molecular biology of the dopamine receptors

1991 • 247 citations

The Effects of a Selective D4 Dopamine Receptor Antagonist (L-745,870) in Acutely Psychotic Inpatients With Schizophrenia

1997 • 195 citations

Developments in the drug treatment of schizophrenia

1992 • 154 citations

Clinical Efficacy of Clozapine in Treatment-Refractory Schizophrenia: An Overview

1992 • 145 citations

Differential effects of classical and newer antipsychotics on the hypermotility induced by two dose levels of d-amphetamine

1995 • 139 citations

Clozapine-Associated Agranulocytosis: Risk and Aetiology

1992 • 123 citations

The paw test: a behavioural paradigm for differentiating between classical and atypical neuroleptic drugs

1987 • 92 citations

The use of 2-oxazolidinones as latent aziridine equivalents. 2. Aminoethylation of aromatic amines, phenols, and thiophenols

1992 • 48 citations

An asymmetric route to enantiomerically pure 1,2,3-trisubstituted cyclopropanes

1992 • 48 citations

Effect of antipsychotic and other classes of drugs on spontaneous locomotor activity and neurotoxicity in mice

1978 • 14 citations