Use of water-insoluble enzyme derivatives in biochemical analysis and separation

The hydrolysis of rabbit γ-globulin and antibodies with crystalline papain

1959 • 2,294 citations

Chemical Coupling of Peptides and Proteins to Polysaccharides by Means of Cyanogen Halides

1967 • 2,172 citations

The Enzyme Electrode

1967 • 1,250 citations

Chemical Coupling of Proteins to Agarose

1967 • 981 citations

A Method for the Quantitative Modification and Estimation of Carboxylic Acid Groups in Proteins

1967 • 927 citations

Acid and Basic Catalysis.

1928 • 849 citations

A Water-insoluble Polyanionic Derivative of Trypsin. II. Effect of the Polyelectrolyte Carrier on the Kinetic Behavior of the Bound Trypsin^*

1964 • 507 citations

Chemical physics of ionic solutions

1967 • 491 citations

Water-Insoluble Derivatives of Enzymes, Antigens, and Antibodies

1966 • 475 citations

Mechanism of Action of Proteolytic Enzymes

1965 • 473 citations

Chemical physics of ionic solutions

1967 • 294 citations

INTERMOLECULAR CROSS LINKING OF A PROTEIN IN THE CRYSTALLINE STATE: CARBOXYPEPTIDASE-A

1964 • 287 citations

Immunologic Adsorbents

1951 • 270 citations

A Water-insoluble Polyanionic Derivative of Trypsin. I. Preparation and Properties^*

1964 • 239 citations

Purification of antibodies with immunoadsorbents prepared using bromoacetyl cellulose

1967 • 230 citations

The kinetics of carboxymethylcellulose–ficin in packed beds

1966 • 212 citations

Antigens and Enzymes Made Insoluble by Entrapping Them into Lattices of Synthetic Polymers

1963 • 208 citations

The Preparation and Characterization of Lyophilized Polyacrylamide Enzyme Gels for Chemical Analysis.

1966 • 184 citations

Synthesis of Biologically Active Cellulose Derivatives of Enymes

1961 • 177 citations

Preparation and Properties of Water-insoluble Derivatives of Trypsin

1963 • 175 citations

Papain-collodion membranes. I. Preparation and properties

1968 • 167 citations

Preparation of enzymically active, water-insoluble derivatives of trypsin

1967 • 150 citations

Substructure of the myosin molecule as visualized by electron microscopy.

1967 • 142 citations

Coupling of Enzymes to Cellulose using Chloro-s-triazines

1967 • 141 citations

The Activity of an Enzyme in the Crystalline State: Ribonuclease S

1963 • 131 citations

Cross-Linking of Bovine Pancreatic Ribonuclease A with Dimethyl Adipimidate^*

1967 • 129 citations

A Two-stage Cleavage of Rabbit γ-Globulin by a Water-insoluble Papain Preparation Followed by Cysteine

1961 • 129 citations

The preparation and properties of ficin chemically attached to carboxymethylcellulose

1966 • 127 citations

On the Formation of Covalent Linkages between Two Protein Molecules

1961 • 124 citations

Papain Membrane on a Collodion Matrix: Preparation and Enzymic Behavior

1965 • 115 citations

Chemical Coupling of Enzymes to Cross-Linked Dextran (‘Sephadex’)

1966 • 112 citations

The Chemistry and use of cellulose derivatives for the study of biological systems

1965 • 93 citations

Synthese von verbindungen der cellulose mit eiweißstoffen

1949 • 93 citations

The Reversible Reduction of Disulfide Bonds in Trypsin and Ribonuclease Coupled to Carboxymethyl Cellulose

1962 • 93 citations

Proteolytic degradation of myosin and the meromyosins by a water-insoluble polyanionic derivative of trypsin

1967 • 92 citations

Structure of Proteins

1963 • 89 citations

Die Kupplung von Proteinen an diazotiertes Polyaminostyrol

1954 • 86 citations

Effect of local pH changes caused by substrate hydrolysis on the activity of membrane-bound acetylcholinesterase.

1967 • 86 citations

Preparation of Immobilized Cholinesterase for Use in Analytical Chemistry.

1965 • 86 citations

Use of antibody bound to modified cellulose as an immunospecific adsorbent of antigens

1963 • 83 citations

Reactive polymers and their use for the preparation of antibody and enzyme resins

1962 • 80 citations

Fluorometric System Employing Immobilized Cholinesterase for Assaying Anticholinesterase Compounds

1965 • 78 citations

The Coupling of an Enzymatic Reaction to Transmembrane Flow of Electric Current in a Synthetic "Active Transport" System

1967 • 75 citations

Reaktionen von 1,5‐difluor‐2,4‐dinitrobenzol mit insulin 1. Mitt. Synthese von modellverbindungen

1958 • 63 citations

Some water‐insoluble papain derivatives

1966 • 57 citations

Studies on continuous enzyme reactions. 3. Enzymatic properties of the DEAE-cellulose-aminoacylase complex.

1967 • 56 citations

The synthesis and use of some insoluble immunologically specific adsorbents

1964 • 53 citations

The Reaction of Bovine Serum Albumin with the Bifunctional Reagent p,p′-Difluoro-m,m′-dinitro-diphenylsulfone

1961 • 52 citations

Polymorphism in fibrinogen aggregates

1966 • 52 citations

Derivatives of proteins. II. Coupling of α‐chymotrypsin to carboxyl‐containing polymers by use of N‐ethyl‐5‐phenylisoxazolium‐3′‐sulfonate

1967 • 50 citations

Synthesis of poly‐<scp>L</scp>‐arginine

1966 • 46 citations

Preparation and Properties of Water-insoluble Derivatives of Urease

1964 • 45 citations

Über Proteaseinhibitoren, IV. Isolierung von Protease-Inhibitoren mit Hilfe wasserunlöslicher Enzym-Harze

1967 • 45 citations

Immunochemically-active cross-linked polystyrene preparations

1960 • 41 citations

Verwendung eines nitrierten copolymerisates aus methacrylsäure und methacrylsäure‐m‐fluoranilid zur darstellung von enzym‐harzen sowie zu racematspaltungs‐und gerbungsversuchen

1962 • 39 citations

�ber serologisch wirksame Proteinharze und Enzymharze

1964 • 36 citations

Soluble Complexes of Antigen and Antibody Fragments

1962 • 32 citations

Reaktionsfähige hochpolymere auf polystyrolbasis als träger von proteinen und enzymen

1966 • 31 citations

Umsetzungen an copolymerisaten des methacrylsäurefluoranilids

1960 • 29 citations

Enzyme Activities in Polarized Cell Membranes

1968 • 29 citations

Action of Water-Insoluble Trypsin Derivatives on Prothrombin and Related Clotting Factors^*

1966 • 28 citations

Isolation of Proteolytic Enzymes from Solution as Dry Stable Derivatives of Cellulosic Ion Exchangers

1959 • 27 citations

Bifunctional reagents and protein structure determination. The reaction of phenolic disulfonyl chlorides with lysozyme

1964 • 26 citations

Isolierung von Protease-Inhibitoren

1966 • 25 citations

A new technique for the enzymic detection of hydrogen peroxide

1966 • 25 citations

The Effect of Sodium Dodecylsulfate on Intact and Insoluble Papain Hydrolyzed Immune Globulin

1964 • 25 citations

Action of Water-insoluble Trypsin Derivatives on Pepsinogen

1966 • 22 citations

A Comparison of Fragments of Rabbit Antibodies and Normal γ-Globulin by the Peptide-Map Technique^*

1964 • 22 citations

Chemical Coupling of Amino Acids, Peptides, and Proteins to Sephadex.

1964 • 20 citations

New synthesis of poly-l-glutamic acid and poly-l-glutamyl proteins 1

1966 • 19 citations

Binding of thiols by a water-insoluble organomercurial copolymer of ethylene and maleic acid

1967 • 14 citations

Zur Racemattrennung an optisch aktiven Polymeren III

1967 • 13 citations

Antibody-antigen reactions: model systems for the specific interactions of biological macromolecules

1962 • 10 citations

Isolation of Protease Inhibitors

1966 • 10 citations

Untersuchungen an Kollagen

1962 • 8 citations