cAMP signaling mechanisms with aging in rats

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Endothelium‐derived relaxing and contracting factors

1989 • 2,017 citations

Diversity of G Proteins in Signal Transduction

1991 • 1,990 citations

Biosynthesis and Metabolism of Endothelium-Derived Nitric Oxide

1990 • 1,284 citations

Cardiovascular regulatory mechanisms in advanced age.

1993 • 789 citations

Mammalian Membrane-bound Adenylyl Cyclases

1995 • 722 citations

Rapid protein kinase assay using phosphocellulose-paper absorption

1975 • 363 citations

Age-related changes in beta-adrenergic neuroeffector systems in the human heart.

1994 • 283 citations

Role of the endothelium in the vasodilator response of rat thoracic aorta to histamine

1983 • 249 citations

Cardiovascular responses in ageing: a review.

1990 • 200 citations

Decline in beta adrenergic receptor-mediated vascular relaxation with aging in man.

1986 • 187 citations

Changes in type VI adenylyl cyclase isoform expression correlate with a decreased capacity for cAMP generation in the aging ventricle.

1994 • 95 citations

Age-related decrease in beta adrenergic receptor-mediated vascular smooth muscle relaxation.

1986 • 80 citations

Inhibition of lipolysis by adenosine is potentiated with age.

1984 • 65 citations

Relaxing and Contracting Factors

1988 • 59 citations

Role of cyclic AMP-dependent protein kinase in the diminished beta adrenergic responsiveness of vascular smooth muscle with increasing age.

1989 • 59 citations

Forskolin Binding Sites and G-Protein Immunoreactivity in Rat Hearts During Aging

1994 • 36 citations

Endothelium-derived relaxing and contracting factors

1990 • 35 citations

Expression of G Protein Subunits in the Aging Cardiovascular System

1995 • 35 citations

Age-related decrement in hormone-stimulated lipolysis

1984 • 34 citations

Desensitization to parathyroid hormone in renal cells from aged rats is associated with alterations in G-protein activity.

1989 • 33 citations

Thyroxine treatment of aged or young rats demonstrates that vascular responses mediated by β‐adrenoceptor subtypes can be differentially regulated

1986 • 33 citations

Decreased β-adrenoceptor-mediated vasodilation in aorta from aged rats: possible involvement of a stimulatory GTP-binding protean

1991 • 33 citations

Impaired expression of Gsα protein mRNA in rat ventricular myocardium with aging

1994 • 32 citations

A low-sodium diet corrects the defect in beta-adrenergic response in older subjects.

1992 • 26 citations

Effect of age on β-receptors, Gsα- and Giα-proteins in rat heart

1994 • 26 citations

Age-related alterations in adenylyl cyclase system of rat hearts.

1991 • 22 citations

Histamine relaxation of aortic rings from diabetic rats

1989 • 21 citations

Multiple families of Gs-regulated adenylyl cyclases.

1993 • 18 citations

Desensitization of the beta-2 adrenoceptor-mediated vasodilation in rat aorta after prolonged treatment with the beta-2 adrenoceptor agonist clenbuterol.

1990 • 15 citations

Age-related deficit in beta receptor stimulation of cAMP binding in blood vessels

1990 • 14 citations

Age-related change in parathyroid hormone-dependent cyclic AMP formation in rat kidney

1982 • 10 citations

Decrease in Gs protein expression may impair adenylate cyclase activation in old kidneys

1993 • 8 citations